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C7C913

- C7C913_METED

UniProt

C7C913 - C7C913_METED

Protein

Triosephosphate isomerase

Gene

tpiA

Organism
Methylobacterium extorquens (strain DSM 5838 / DM4) (Methylobacterium dichloromethanicum (strain DM4))
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 40 (01 Oct 2014)
      Sequence version 1 (22 Sep 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-glyceraldehyde 3-phosphate = glycerone phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei13 – 131SubstrateUniRule annotation
    Binding sitei15 – 151SubstrateUniRule annotation
    Active sitei100 – 1001ElectrophileUniRule annotation
    Active sitei170 – 1701Proton acceptorUniRule annotation

    GO - Molecular functioni

    1. triose-phosphate isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. gluconeogenesis Source: UniProtKB-HAMAP
    2. glycolytic process Source: UniProtKB-HAMAP
    3. pentose-phosphate shunt Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Biological processi

    GluconeogenesisUniRule annotationSAAS annotation, GlycolysisUniRule annotationSAAS annotation, Pentose shuntUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciMEXT661410:GJA1-5625-MONOMER.
    UniPathwayiUPA00109; UER00189.
    UPA00138.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Triosephosphate isomeraseUniRule annotation (EC:5.3.1.1UniRule annotation)
    Short name:
    TIMUniRule annotation
    Alternative name(s):
    Triose-phosphate isomeraseUniRule annotation
    Gene namesi
    Name:tpiAUniRule annotationImported
    Ordered Locus Names:METDI5716Imported
    OrganismiMethylobacterium extorquens (strain DSM 5838 / DM4) (Methylobacterium dichloromethanicum (strain DM4))Imported
    Taxonomic identifieri661410 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesMethylobacteriaceaeMethylobacterium
    ProteomesiUP000008070: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Subunit structurei

    Homodimer.UniRule annotationSAAS annotation

    Protein-protein interaction databases

    STRINGi661410.METDI5716.

    Structurei

    3D structure databases

    ProteinModelPortaliC7C913.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the triosephosphate isomerase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0149.
    HOGENOMiHOG000226414.
    KOiK01803.
    OMAiDNAREIM.
    OrthoDBiEOG66QM23.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_00147_B. TIM_B.
    InterProiIPR013785. Aldolase_TIM.
    IPR022896. TrioseP_Isoase_bac/euk.
    IPR000652. Triosephosphate_isomerase.
    IPR020861. Triosephosphate_isomerase_AS.
    [Graphical view]
    PANTHERiPTHR21139. PTHR21139. 1 hit.
    PfamiPF00121. TIM. 1 hit.
    [Graphical view]
    SUPFAMiSSF51351. SSF51351. 1 hit.
    TIGRFAMsiTIGR00419. tim. 1 hit.
    PROSITEiPS00171. TIM_1. 1 hit.
    PS51440. TIM_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C7C913-1 [UniParc]FASTAAdd to Basket

    « Hide

    MASEGRRPLV AGNWKMNGLL SSVPTVEAIR DGLSPALADK IDVLICPPAT    50
    LISSCVAAVY GSVVAIGGQN LHARPSGAFT GSISAEMFAD LGATYVIVGH 100
    SERRAYHYET DDGVHAKALG ARRAGLRGII CVGETMEERQ QGRALDIVRA 150
    QLAIGLPKGA TGADTVIAYE PVWAIGSGRT PTATEIAEVH ASLREMLDKL 200
    VGEEAHKIRI LYGGSVKPSN ARELMAVENV DGALVGGASL VAEDFLGICR 250
    AYEG 254
    Length:254
    Mass (Da):26,563
    Last modified:September 22, 2009 - v1
    Checksum:i0F35FB416B7D4E0E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FP103042 Genomic DNA. Translation: CAX27320.1.
    RefSeqiYP_003071125.1. NC_012988.1.

    Genome annotation databases

    EnsemblBacteriaiCAX27320; CAX27320; METDI5716.
    GeneIDi8194883.
    KEGGimdi:METDI5716.
    PATRICi22529885. VBIMetExt143287_5445.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FP103042 Genomic DNA. Translation: CAX27320.1 .
    RefSeqi YP_003071125.1. NC_012988.1.

    3D structure databases

    ProteinModelPortali C7C913.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 661410.METDI5716.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAX27320 ; CAX27320 ; METDI5716 .
    GeneIDi 8194883.
    KEGGi mdi:METDI5716.
    PATRICi 22529885. VBIMetExt143287_5445.

    Phylogenomic databases

    eggNOGi COG0149.
    HOGENOMi HOG000226414.
    KOi K01803.
    OMAi DNAREIM.
    OrthoDBi EOG66QM23.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00189 .
    UPA00138 .
    BioCyci MEXT661410:GJA1-5625-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_00147_B. TIM_B.
    InterProi IPR013785. Aldolase_TIM.
    IPR022896. TrioseP_Isoase_bac/euk.
    IPR000652. Triosephosphate_isomerase.
    IPR020861. Triosephosphate_isomerase_AS.
    [Graphical view ]
    PANTHERi PTHR21139. PTHR21139. 1 hit.
    Pfami PF00121. TIM. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51351. SSF51351. 1 hit.
    TIGRFAMsi TIGR00419. tim. 1 hit.
    PROSITEi PS00171. TIM_1. 1 hit.
    PS51440. TIM_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: DSM 5838 / DM4Imported.

    Entry informationi

    Entry nameiC7C913_METED
    AccessioniPrimary (citable) accession number: C7C913
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 22, 2009
    Last sequence update: September 22, 2009
    Last modified: October 1, 2014
    This is version 40 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3