C7C6X7 (C7C6X7_METED) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
[Protein-PII] uridylyltransferase HAMAP-Rule MF_00277
Short name=PII uridylyl-transferase HAMAP-Rule MF_00277
EC=2.7.7.59 HAMAP-Rule MF_00277

Alternative name(s):
UTase HAMAP-Rule MF_00277
Uridylyl-removing enzyme HAMAP-Rule MF_00277

Gene names

Name:	glnD HAMAP-Rule MF_00277 EMBL CAX21881.1
Ordered Locus Names:	METDI0212 EMBL CAX21881.1

Organism

Methylobacterium extorquens (strain DSM 5838 / DM4) (Methylobacterium dichloromethanicum (strain DM4)) [Complete proteome] [HAMAP] EMBL CAX21881.1

Taxonomic identifier

661410 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium › Methylobacterium extorquens group › Methylobacterium extorquens

Protein attributes

Sequence length	928 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein By similarity. HAMAP-Rule MF_00277 SAAS SAAS010043
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP-Rule MF_00277 SAAS SAAS010043
Sequence similarities	Belongs to the GlnD family. HAMAP-Rule MF_00277

Ontologies

Keywords
Molecular function	Nucleotidyltransferase HAMAP-Rule MF_00277 SAAS SAAS010043 EMBL CAX21881.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	nitrogen fixation Inferred from electronic annotation. Source: HAMAP
Molecular_function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP amino acid binding Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro phosphoric diester hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C7C6X7 [UniParc]. Last modified September 22, 2009. Version 1. Checksum: D3C1E4F56083055A	FASTA	928	104,425
	10 20 30 40 50 60 MFDPVPVLEK IVASLDRDAR EPTKLRGLLV PELRKVIETG HAEAERLLLK ERDGLACAQR 70 80 90 100 110 120 LSRLTDAVVR AIYDAVVWRL YPNDNPSTGE HLAIVATGGY GRGTMAPGSD IDLLFLLPYK 130 140 150 160 170 180 QTAWSESVVE AMLYVLWDLK LKVGHATRSV EECLREGRAD MTIRTALLES RFLFGSRSLF 190 200 210 220 230 240 EEMVTRFDTE LVIGSASEFV DAKLRERDAR VAKAGASRYL VEPNVKDGKG GLRDLNTLFW 250 260 270 280 290 300 IAKYTYRVRN QAELVHAGLF TPDEYRLFER CEEFLWRVRC HIHFVTGRPE ERLSFGLQPK 310 320 330 340 350 360 IAERLGFGSR GGLSGVERFM KAYFLIAKDV GDLTAIVCAE LEARHAKRTP VLDRWIGRFR 370 380 390 400 410 420 DRFRATSIEA EDFWIDNGRV NIRGEDAFER DPVNLIRLFW LADRHNLPIH PDAARLANRS 430 440 450 460 470 480 LKLITHAVRI DPEANRLFLD ILTSKNAPET ILRSMNEAGV LGRFIPEFGR IVAMMQFNMY 490 500 510 520 530 540 HHYTVDEHLL RSLGVLAAID SGRVRDEHPL ASRLIDTIHN RRALYVAILL HDIAKGRPED 550 560 570 580 590 600 HSIAGAAIAR KLGPRFGLSQ AETETVSWLV EHHLLMSMTA QSRDLSDRRT IEKFASEVQS 610 620 630 640 650 660 LERLKLLAIL TVADIKAVGP GVWTAWKGTL LRTLYDETEV VLSGGHSEIA RTDRVRLIQM 670 680 690 700 710 720 ALREQLSDWN SELFDGYAAR HNQAYWLKVD STRHFKNARF LRTVMEEGRT SATTYETDPV 730 740 750 760 770 780 RGVTELTVYS PDHPRLLAII TGACATMGGN IVDAQIFTTT DGFALDSIFI SRAFERDEDE 790 800 810 820 830 840 LRRAGRIATA IERALKGEIK IAELVADKHP KQPPKTFLVP PDVSIDNALS SRETVVEITG 850 860 870 880 890 900 LDRPGLLYEL TTGLNRLSLN ITSAHVATFG ERAVDVFYVT DLTGTRVVQP DRLAMIRAAV 910 920 MEVFASDVAA LRAEGLDALV DSPPPREL

References

[1]

"Methylobacterium genome sequences: a reference blueprint to investigate microbial metabolism of C1 compounds from natural and industrial sources." Vuilleumier S., Chistoserdova L., Lee M.C., Bringel F., Lajus A., Zhou Y., Gourion B., Barbe V., Chang J., Cruveiller S., Dossat C., Gillett W., Gruffaz C., Haugen E., Hourcade E., Levy R., Mangenot S., Muller E. , Nadalig T., Pagni M., Penny C., Peyraud R., Robinson D.G., Roche D., Rouy Z., Saenampechek C., Salvignol G., Vallenet D., Wu Z., Marx C.J., Vorholt J.A., Olson M.V., Kaul R., Weissenbach J., Medigue C., Lidstrom M.E. PLoS ONE 4:E5584-E5584(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 5838 / DM4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FP103042 Genomic DNA. Translation: CAX21881.1.
RefSeq	YP_003065946.1. NC_012988.1.
3D structure databases
ProteinModelPortal	C7C6X7.
ModBase	Search...
Protein-protein interaction databases
STRING	661410.METDI0212.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAX21881; CAX21881; METDI0212.
GeneID	8190687.
KEGG	mdi:METDI0212.
PATRIC	22519508. VBIMetExt143287_0329.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2844.
HOGENOM	HOG000261779.
KO	K00990.
OMA	SPKVWNA.
ProtClustDB	PRK05092.
Enzyme and pathway databases
BioCyc	MEXT661410:GJA1-205-MONOMER.
Family and domain databases
Gene3D	1.10.3210.10. 1 hit.
HAMAP	MF_00277. PII_uridylyl_transf.
InterPro	IPR002912. ACT_dom. IPR010043. GlnD_Uridyltrans. IPR003607. HD/PDEase_dom. IPR006674. HD_domain. IPR002934. Nucleotidyltransferase. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
PANTHER	PTHR13734:SF1. PTHR13734:SF1. 1 hit.
Pfam	PF01842. ACT. 2 hits. PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. PF01909. NTP_transf_2. 1 hit. [Graphical view]
PIRSF	PIRSF006288. PII_uridyltransf. 1 hit.
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01693. UTase_glnD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C7C6X7_METED

Accession

Primary (citable) accession number: C7C6X7

Entry history

Integrated into UniProtKB/TrEMBL:	September 22, 2009
Last sequence update:	September 22, 2009
Last modified:	May 1, 2013
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)