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C7BYY8 (C7BYY8_HELPB) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length377 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS001608

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site371Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2711Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1351Substrate By similarity HAMAP-Rule MF_01201
Binding site3191Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue371N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
C7BYY8 [UniParc].

Last modified September 22, 2009. Version 1.
Checksum: C9C7127EE08697D6

FASTA37741,920
        10         20         30         40         50         60 
MLKRASFVEV DTASLRHNFS AVKSIIPKDA CVMAVVKANA YGVGAIKASE IFLQEGANYL 

        70         80         90        100        110        120 
GVAALDEALE LRSYFSKTPI LILGYSPNSN ASMLIDNDLS AMVFSFEQAE VFSQMALKSQ 

       130        140        150        160        170        180 
KRLKVHLKID TGMHRLGLEP NFKSIEIIKK IRALKGLEVE GIFTHLSNAD AKIKTHAKNQ 

       190        200        210        220        230        240 
MKAFNAFLEQ LLDQKIEFQY RHAYNSAGIL SLCNGNENRF LNLYRPGIML YGFYPSNEMK 

       250        260        270        280        290        300 
ESCPTILKNV VSLKAQIVQI RSVKKGEFIG YGEHFYTNEE TLVGVLALGY ADGLVRALGN 

       310        320        330        340        350        360 
RIQVAINNQL APLIGKVCMD QCFVKLNDIQ AKEGDEVILF GDKSTKANDA SEIAVLLNTI 

       370 
PYETISTLSK RLERVYI 

« Hide

References

[1]"From array-based hybridization of Helicobacter pylori isolates to the complete genome sequence of an isolate associated with MALT lymphoma."
Thiberge J.M., Boursaux-Eude C., Lehours P., Dillies M.A., Creno S., Coppee J.Y., Rouy Z., Lajus A., Ma L., Burucoa C., Ruskone-Foumestraux A., Courillon-Mallet A., De Reuse H., Boneca I.G., Lamarque D., Megraud F., Delchier J.C., Medigue C. expand/collapse author list , Bouchier C., Labigne A., Raymond J.
BMC Genomics 11:368-368(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: B38 EMBL CAX29451.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
FM991728 Genomic DNA. Translation: CAX29451.1.
RefSeqYP_003057645.1. NC_012973.1.

3D structure databases

ProteinModelPortalC7BYY8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING592205.HELPY_0927.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAX29451; CAX29451; HELPY_0927.
GeneID8207992.
KEGGhpb:HELPY_0927.
PATRIC20596506. VBIHelPyl144313_0928.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0787.
HOGENOMHOG000031444.
KOK01775.
OMAFIMSHLA.
OrthoDBEOG6PP9NJ.

Enzyme and pathway databases

BioCycHPYL592205:GJAG-909-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC7BYY8_HELPB
AccessionPrimary (citable) accession number: C7BYY8
Entry history
Integrated into UniProtKB/TrEMBL: September 22, 2009
Last sequence update: September 22, 2009
Last modified: July 9, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)