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C7BNE5

- C7BNE5_PHOAA

UniProt

C7BNE5 - C7BNE5_PHOAA

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Protein

Alanine racemase

Gene

alr

Organism
Photorhabdus asymbiotica subsp. asymbiotica (strain ATCC 43949 / 3105-77) (Xenorhabdus luminescens (strain 2))
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei34 – 341Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei129 – 1291SubstrateUniRule annotation
Active sitei254 – 2541Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei302 – 3021Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciPASY291112:GJQ0-4038-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Name:alrImported
Ordered Locus Names:PAU_03912Imported
OrganismiPhotorhabdus asymbiotica subsp. asymbiotica (strain ATCC 43949 / 3105-77) (Xenorhabdus luminescens (strain 2))Imported
Taxonomic identifieri553480 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePhotorhabdus
ProteomesiUP000002747: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei34 – 341N6-(pyridoxal phosphate)lysineUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi291112.PAU_03912.

Structurei

3D structure databases

ProteinModelPortaliC7BNE5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000031446.
KOiK01775.
OMAiLWQLEAI.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C7BNE5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKAATAVIDR RALRHNLQRV REIAPKSNLI AVVKANAYGH GLLETAHTLD
60 70 80 90 100
DADCFGVARI GEALTLRHGG IVKPILLLEG CFDAADLPVL VANHIETVVH
110 120 130 140 150
SIEQLEALEQ AKLSHPVKVW MKLDSGMHRL GVRPEDAEEF YQRLSRCKNV
160 170 180 190 200
QQPVNIVSHF GRADEPTLDT TCQQIACFQA FCADKPGEKS IDASGGILLW
210 220 230 240 250
PEVHQDWVRP GLMMYGVSPL SDKTAADFNL MPAMTLKSSL IAVRKHKAGE
260 270 280 290 300
AVGYGGTWIS ERDTCLGVVA IGYGDGYPRC APSGTPIYIN GREVPIAGRV
310 320 330 340 350
SMDMISVDLG PDAADKVGDE AVLWGDVLPV ERIAECTGII TYELVTKLTS

RVVMEYLDE
Length:359
Mass (Da):39,123
Last modified:September 22, 2009 - v1
Checksum:iCBA5D1DF50888C20
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FM162591 Genomic DNA. Translation: CAQ86000.1.
RefSeqiYP_003042741.1. NC_012962.1.

Genome annotation databases

EnsemblBacteriaiCAQ86000; CAQ86000; PAU_03912.
GeneIDi13859436.
KEGGipay:PAU_03912.
PATRICi20502324. VBIPhoAsy71438_4398.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FM162591 Genomic DNA. Translation: CAQ86000.1 .
RefSeqi YP_003042741.1. NC_012962.1.

3D structure databases

ProteinModelPortali C7BNE5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 291112.PAU_03912.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAQ86000 ; CAQ86000 ; PAU_03912 .
GeneIDi 13859436.
KEGGi pay:PAU_03912.
PATRICi 20502324. VBIPhoAsy71438_4398.

Phylogenomic databases

HOGENOMi HOG000031446.
KOi K01775.
OMAi LWQLEAI.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci PASY291112:GJQ0-4038-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43949 / 3105-77Imported.

Entry informationi

Entry nameiC7BNE5_PHOAA
AccessioniPrimary (citable) accession number: C7BNE5
Entry historyi
Integrated into UniProtKB/TrEMBL: September 22, 2009
Last sequence update: September 22, 2009
Last modified: October 29, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3