SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

C7BHW3

- C7BHW3_PHOAA

UniProt

C7BHW3 - C7BHW3_PHOAA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Gamma-glutamyl phosphate reductase
Gene
proA, PAU_03217
Organism
Photorhabdus asymbiotica subsp. asymbiotica (strain ATCC 43949 / 3105-77) (Xenorhabdus luminescens (strain 2))
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the NADPH dependent reduction of L-gamma-glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate By similarity.UniRule annotationSAAS annotations

Catalytic activityi

L-glutamate 5-semialdehyde + phosphate + NADP+ = L-glutamyl 5-phosphate + NADPH.UniRule annotationSAAS annotations

Pathwayi

GO - Molecular functioni

  1. NADP binding Source: InterPro
  2. glutamate-5-semialdehyde dehydrogenase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. L-proline biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationSAAS annotations

Keywords - Biological processi

Amino-acid biosynthesis, Proline biosynthesisUniRule annotationSAAS annotations

Keywords - Ligandi

NADPUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciPASY291112:GJQ0-3333-MONOMER.
UniPathwayiUPA00098; UER00360.

Names & Taxonomyi

Protein namesi
Recommended name:
Gamma-glutamyl phosphate reductaseUniRule annotation (EC:1.2.1.41UniRule annotation)
Short name:
GPRUniRule annotation
Alternative name(s):
Glutamate-5-semialdehyde dehydrogenase
Glutamyl-gamma-semialdehyde dehydrogenase
Gene namesi
Name:proAUniRule annotation
Ordered Locus Names:PAU_03217Imported
OrganismiPhotorhabdus asymbiotica subsp. asymbiotica (strain ATCC 43949 / 3105-77) (Xenorhabdus luminescens (strain 2))
Taxonomic identifieri553480 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePhotorhabdus
ProteomesiUP000002747: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotationSAAS annotations

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotations

Interactioni

Protein-protein interaction databases

STRINGi291112.PAU_03217.

Structurei

3D structure databases

ProteinModelPortaliC7BHW3.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000246356.
KOiK00147.
OMAiALTSYKW.
OrthoDBiEOG6FFSCX.

Family and domain databases

Gene3Di3.40.309.10. 1 hit.
3.40.605.10. 2 hits.
HAMAPiMF_00412. ProA.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR000965. G-glutamylP_reductase.
IPR020593. G-glutamylP_reductase_CS.
IPR012134. Glu-5-SA_DH.
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
[Graphical view]
PIRSFiPIRSF000151. GPR. 1 hit.
SUPFAMiSSF53720. SSF53720. 1 hit.
TIGRFAMsiTIGR00407. proA. 1 hit.
PROSITEiPS01223. PROA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C7BHW3-1 [UniParc]FASTAAdd to Basket

« Hide

MLEQMGKAAR EASWQLAQLS TKQKNQALIH IADLLEQESA VILEANQLDM    50
IQAREQGMNE ALLDRLLLTS ERLTAIANDV RQVCRLSDPV GQIIDGSLLD 100
SGLKLERRRV PLGVVGVIYE ARPNVTIDVA SLCLKTGNAV ILRGGKETHN 150
TNQATVKVIQ RALEQSGLPA AAVQVIDKPD RELVTQLLKM DRYVDMLIPR 200
GGAGLHKLCR EQSTIPVITG GIGVCHIFVD ESVDFNQALT VITNAKVQRP 250
SACNALETLL VHEKIAADFL PALSENMKAQ GVTLHASKSA MEFLLEGPAK 300
VVEVTEVDYS DEWLSLDMNV EIVSDIEQAI NHIRTYGTSH SDAILTQSLH 350
NADYFVRQVD SAAVYVNAST RFTDGGQFGL GAEVAVSTQK LHARGPMGLD 400
ALTTYKWVGY GDDLIRQ 417
Length:417
Mass (Da):45,541
Last modified:September 22, 2009 - v1
Checksum:i8D4AF9D75CD60662
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FM162591 Genomic DNA. Translation: CAQ85305.1.
RefSeqiYP_003042047.1. NC_012962.1.

Genome annotation databases

EnsemblBacteriaiCAQ85305; CAQ85305; PAU_03217.
GeneIDi13860018.
KEGGipay:PAU_03217.
PATRICi20500756. VBIPhoAsy71438_3616.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FM162591 Genomic DNA. Translation: CAQ85305.1 .
RefSeqi YP_003042047.1. NC_012962.1.

3D structure databases

ProteinModelPortali C7BHW3.
ModBasei Search...

Protein-protein interaction databases

STRINGi 291112.PAU_03217.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAQ85305 ; CAQ85305 ; PAU_03217 .
GeneIDi 13860018.
KEGGi pay:PAU_03217.
PATRICi 20500756. VBIPhoAsy71438_3616.

Phylogenomic databases

HOGENOMi HOG000246356.
KOi K00147.
OMAi ALTSYKW.
OrthoDBi EOG6FFSCX.

Enzyme and pathway databases

UniPathwayi UPA00098 ; UER00360 .
BioCyci PASY291112:GJQ0-3333-MONOMER.

Family and domain databases

Gene3Di 3.40.309.10. 1 hit.
3.40.605.10. 2 hits.
HAMAPi MF_00412. ProA.
InterProi IPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR000965. G-glutamylP_reductase.
IPR020593. G-glutamylP_reductase_CS.
IPR012134. Glu-5-SA_DH.
[Graphical view ]
Pfami PF00171. Aldedh. 1 hit.
[Graphical view ]
PIRSFi PIRSF000151. GPR. 1 hit.
SUPFAMi SSF53720. SSF53720. 1 hit.
TIGRFAMsi TIGR00407. proA. 1 hit.
PROSITEi PS01223. PROA. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43949 / 3105-77.

Entry informationi

Entry nameiC7BHW3_PHOAA
AccessioniPrimary (citable) accession number: C7BHW3
Entry historyi
Integrated into UniProtKB/TrEMBL: September 22, 2009
Last sequence update: September 22, 2009
Last modified: May 14, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi