C6ZRJ9 (C6ZRJ9_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: TCF7L2 isoform pFC8A_TCF7L2_H7_ex1-11-13-13b EMBL ACI28526.1
Organism	Homo sapiens (Human) EMBL ACI28526.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	455 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological_process	Wnt receptor signaling pathway Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C6ZRJ9 [UniParc]. Last modified September 22, 2009. Version 1. Checksum: EF7FBE721FB99935	FASTA	455	50,721
	10 20 30 40 50 60 MPQLNGGGGD DLGANDELIS FKDEGEQEEK SSENSSAERD LADVKSSLVN ESETNQNSSS 70 80 90 100 110 120 DSEAERRPPP RSESFRDKSR ESLEEAAKRQ DGGLFKGPPY PGYPFIMIPD LTSPYLPNGS 130 140 150 160 170 180 LSPTARTYLQ MKWPLLDVQA GSLQSRQALK DARSPSPAHI VSNKVPVVQH PHHVHPLTPL 190 200 210 220 230 240 ITYSNEHFTP GNPPPHLPAD VDPKTGIPRP PHPPDISPYY PLSPGTVGQI PHPLGWQGQP 250 260 270 280 290 300 VYPITTGGFR HPYPTALTVN ASMSRFPPHM VPPHHTLHTT GIPHPAIVTP TVKQESSQSD 310 320 330 340 350 360 VGSLHSSKHQ DSKKEEEKKK PHIKKPLNAF MLYMKEMRAK VVAECTLKES AAINQILGRR 370 380 390 400 410 420 WHALSREEQA KYYELARKER QLHMQLYPGW SARDNYGKKK KRKRDKQPGE TNEHSECFLN 430 440 450 PCLSLPPITD LSAPKKCRAR FGLDQQNNWC GPCSL

References

[1]	"Tissue-specific alternative splicing of TCF7L2." Prokunina-Olsson L., Welch C., Hansson O., Adhikari N., Scott L., Usher N., Tong M., Sprau A., Swift A., Bonnycastle L., Erdos M., He Z., Saxena R., Harmon B., Kotova O., Hoffman E., Altshuler D., Groop L. , Boehnke M., Collins F., Hall J.L. Hum. Mol. Genet. 0:0-0(2009) Cited for: NUCLEOTIDE SEQUENCE. Tissue: Brain EMBL ACI28526.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FJ010168 mRNA. Translation: ACI28526.1.
IPI	IPI00975648.
RefSeq	NP_001185456.1. NM_001198527.1.
UniGene	Hs.593995.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	C6ZRJ9.
Proteomic databases
PRIDE	C6ZRJ9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	6934.
KEGG	hsa:6934.
UCSC	uc010qrq.2. human.
Organism-specific databases
CTD	6934.
Phylogenomic databases
KO	K04491.
Gene expression databases
ArrayExpress	C6ZRJ9.
Bgee	C6ZRJ9.
Family and domain databases
Gene3D	1.10.30.10. 1 hit.
InterPro	IPR013558. CTNNB1-bd_N. IPR009071. HMG_box_dom. IPR024940. TCF/LEF. [Graphical view]
PANTHER	PTHR10373. PTHR10373. 1 hit.
Pfam	PF08347. CTNNB1_binding. 1 hit. PF00505. HMG_box. 1 hit. [Graphical view]
SMART	SM00398. HMG. 1 hit. [Graphical view]
SUPFAM	SSF47095. HMG-box. 1 hit.
PROSITE	PS50118. HMG_BOX_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	6934.
NextBio	27133.

Entry information

Entry name

C6ZRJ9_HUMAN

Accession

Primary (citable) accession number: C6ZRJ9

Entry history

Integrated into UniProtKB/TrEMBL:	September 22, 2009
Last sequence update:	September 22, 2009
Last modified:	May 1, 2013
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.