C6Y105 (C6Y105_PEDHD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
L-arabinose isomerase HAMAP MF_00519
EC=5.3.1.4 HAMAP MF_00519

Gene names

Name:	araA HAMAP MF_00519
Ordered Locus Names:	Phep_2731

Organism

Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / NCIB 9290) [Complete proteome] [HAMAP]

Taxonomic identifier

485917 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Sphingobacteriia › Sphingobacteriales › Sphingobacteriaceae › Pedobacter

Protein attributes

Sequence length	496 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of L-arabinose to L-ribulose By similarity. HAMAP MF_00519 SAAS SAAS003762
Catalytic activity	L-arabinose = L-ribulose. HAMAP MF_00519 SAAS SAAS003762
Cofactor	Binds 1 manganese ion per subunit By similarity. HAMAP MF_00519 SAAS SAAS003762
Pathway	Carbohydrate degradation; L-arabinose degradation via L-ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route): step 1/3. HAMAP MF_00519 SAAS SAAS003762
Sequence similarities	Belongs to the arabinose isomerase family. HAMAP MF_00519

Ontologies

Keywords
Biological process	Arabinose catabolism HAMAP MF_00519 SAAS SAAS003762 Carbohydrate metabolism
Ligand	Manganese HAMAP MF_00519 SAAS SAAS003762 Metal-binding HAMAP MF_00519 SAAS SAAS003762
Molecular function	Isomerase HAMAP MF_00519 SAAS SAAS003762 EMBL ACU04932.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arabinose catabolic process Inferred from electronic annotation. Source: HAMAP fucose metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	L-arabinose isomerase activity Inferred from electronic annotation. Source: HAMAP L-fucose isomerase activity Inferred from electronic annotation. Source: InterPro manganese ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Metal binding	306	1	Manganese By similarity HAMAP MF_00519
	Metal binding	333	1	Manganese By similarity HAMAP MF_00519
	Metal binding	350	1	Manganese By similarity HAMAP MF_00519
	Metal binding	449	1	Manganese By similarity HAMAP MF_00519

Sequences

	Sequence		Length	Mass (Da)
	C6Y105 [UniParc]. Last modified September 22, 2009. Version 1. Checksum: 7ADF5D65D99F185A	FASTA	496	55,235
	10 20 30 40 50 60 MINLKNLEVW FITGTQDLYG EETLKQVAKH AQQVAASLDA AAAIHVSIVY KPIVKTPQEI 70 80 90 100 110 120 FDTLQQANQS KNCIGVMTWM HTFSPAKMWI RGLNILQKPL LHLHTQFNRD IPWATIDMDF 130 140 150 160 170 180 MNLNQSAHGD REFGFMVTRM RKDRKVVVGH WQDEEAIKEI DTWTRAAAGW HDWQGARFVR 190 200 210 220 230 240 FGDNMRYVAV TDGDKVEAEL KFGFEVNTYG IGDLVAVIDS IPEAAIQELI TEYEATYTMT 250 260 270 280 290 300 ADLLRGGERH DSVYQAAKIE LGLKKFLEDG NFKGFSDTFE DLHGMVQLPG IAAQRLMAAG 310 320 330 340 350 360 YGFAGEGDWK TAALVRACKV MGAGLPGTSA FMEDYTYHFD PANAMVLGSH MLEVDAALAN 370 380 390 400 410 420 GKARLEVHPL GIGGKADPAR LIFNVAGGHA LNASIVDMGN RFRLLVNEVE ALEPEHELPN 430 440 450 460 470 480 LPVAQVLWKP LPDMKTGCAA WIYAGGAHHT AYSQNLSPAH LLDFANIAGI EYVNIGADTR 490 INQFRNELHW NETFYK

References

[1]

"Complete genome sequence of Pedobacter heparinus type strain (HIM 762-3)." Han C., Spring S., Lapidus A., Glavina del Rio T., Tice H., Copeland A., Cheng J.-F., Lucas S., Chen F., Nolan M., Bruce D., Goodwin L., Pitluck S., Ivanova N., Mavromatis K., Mikhailova N., Pati A., Chen A. , Palaniappan K., Land M., Hauser L., Chang Y.-J., Jeffries C.C., Saunders E., Chertkov O., Brettin T., Goeker M., Rohde M., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N., Klenk H.-P., Detter J.C. Stand. Genomic Sci. 1:54-62(2009) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 13125 / DSM 2366 / NCIB 9290.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001681 Genomic DNA. Translation: ACU04932.1.
RefSeq	YP_003092994.1. NC_013061.1.
3D structure databases
ProteinModelPortal	C6Y105.
ModBase	Search...
Protein-protein interaction databases
STRING	C6Y105.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8253839.
GenomeReviews	Gene locus Phep_2731 in contig CP001681_GR.
KEGG	phe:Phep_2731.
PATRIC	22882565. VBIPedHep98714_2758.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	EVCPTIA.
ProtClustDB	PRK02929.
Family and domain databases
HAMAP	MF_00519. Arabinose_Isome. [Tree]
InterPro	IPR024664. Ara_Isoase_C. IPR004216. Fuc/Ara_isomerase_C. IPR009015. Fucose_isomerase_N/cen. IPR003762. Lara_isomerase. [Graphical view]
KO	K01804.
Pfam	PF11762. Arabinose_Iso_C. 1 hit. PF02610. Arabinose_Isome. 1 hit. [Graphical view]
PIRSF	PIRSF001478. L-ara_isomerase. 1 hit.
ProDom	PD018364. Lara_isomerase. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF50443. Fuc_isomerase_C. 1 hit. SSF53743. Fuc_isomerase_N. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C6Y105_PEDHD

Accession

Primary (citable) accession number: C6Y105

Entry history

Integrated into UniProtKB/TrEMBL:	September 22, 2009
Last sequence update:	September 22, 2009
Last modified:	December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)