ID   C6XTD0_PEDHD            Unreviewed;       632 AA.
AC   C6XTD0;
DT   22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   22-SEP-2009, sequence version 1.
DT   27-MAR-2024, entry version 70.
DE   RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE            EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
GN   OrderedLocusNames=Phep_3517 {ECO:0000313|EMBL:ACU05708.1};
OS   Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457
OS   / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3).
OC   Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC   Sphingobacteriaceae; Pedobacter.
OX   NCBI_TaxID=485917 {ECO:0000313|EMBL:ACU05708.1, ECO:0000313|Proteomes:UP000000852};
RN   [1] {ECO:0000313|EMBL:ACU05708.1, ECO:0000313|Proteomes:UP000000852}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 /
RC   NCIMB 9290 / NRRL B-14731 / HIM 762-3
RC   {ECO:0000313|Proteomes:UP000000852};
RX   PubMed=21304637; DOI=10.4056/sigs.22138;
RA   Han C., Spring S., Lapidus A., Del Rio T.G., Tice H., Copeland A.,
RA   Cheng J.F., Lucas S., Chen F., Nolan M., Bruce D., Goodwin L., Pitluck S.,
RA   Ivanova N., Mavromatis K., Mikhailova N., Pati A., Chen A., Palaniappan K.,
RA   Land M., Hauser L., Chang Y.J., Jeffries C.C., Saunders E., Chertkov O.,
RA   Brettin T., Goker M., Rohde M., Bristow J., Eisen J.A., Markowitz V.,
RA   Hugenholtz P., Kyrpides N.C., Klenk H.P., Detter J.C.;
RT   "Complete genome sequence of Pedobacter heparinus type strain (HIM 762-
RT   3).";
RL   Stand. Genomic Sci. 1:54-62(2009).
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DR   EMBL; CP001681; ACU05708.1; -; Genomic_DNA.
DR   RefSeq; WP_015809317.1; NZ_AQGK01000001.1.
DR   AlphaFoldDB; C6XTD0; -.
DR   STRING; 485917.Phep_3517; -.
DR   KEGG; phe:Phep_3517; -.
DR   eggNOG; COG0365; Bacteria.
DR   HOGENOM; CLU_000022_3_6_10; -.
DR   OrthoDB; 9778383at2; -.
DR   Proteomes; UP000000852; Chromosome.
DR   GO; GO:0003987; F:acetate-CoA ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016208; F:AMP binding; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019427; P:acetyl-CoA biosynthetic process from acetate; IEA:InterPro.
DR   CDD; cd05966; ACS; 1.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR011904; Ac_CoA_lig.
DR   InterPro; IPR032387; ACAS_N.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   NCBIfam; TIGR02188; Ac_CoA_lig_AcsA; 1.
DR   PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR   PANTHER; PTHR24095:SF14; ACETYL-COENZYME A SYNTHETASE 1; 1.
DR   Pfam; PF16177; ACAS_N; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:ACU05708.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000852}.
FT   DOMAIN          9..64
FT                   /note="Acetyl-coenzyme A synthetase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16177"
FT   DOMAIN          66..452
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          514..592
FT                   /note="AMP-binding enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13193"
SQ   SEQUENCE   632 AA;  70713 MW;  027EEF64F2E0A401 CRC64;
     MQIKSFEEYQ KTYQYSVDYP EQFWEGIANN FQWRKKWNKV LSWNFSEPNI KWFEGAKLNI
     TENCLDRHLA ENGDKPAIIW EPNDPQKESI TLSYKILHEQ VCRFGNVLKK NGVKKGDRVC
     IYMPMVPELA VAVLACARIG AVHSVVFGGF SAKSIADRIN DAECKVVITA DGAFRGNKQI
     QLKEVIDDAL IGCPTVERVI VLTHTRMAVS MLKGRDVWWE DEIKLVDTNC PAEEMDAEDL
     LFILYTSGST GKPKGVVHTI GGYMVYAGYT FSNVFNYQPD EVFFCTADIG WITGHSYIVY
     GPLSQGATTL MFEGIPTFPD ASRMWQVVEK HKVNILYTAP TAIRSLMSFG EEPLKGIDLS
     SLRVLGSVGE PINEEAWHWF DENIGKSKCP IVDTWWQTET GGIMISPIAY VTPTKPSFAT
     LPLPGIQPML VDEQGKEIEG NGVNGNLCIK FPWPGMLRTT YGDHERCKLT YFSTYKDLYF
     TGDGCLRDED GYYRITGRVD DVINVSGHRI GTAEVENAIN MHAGVVESAV VGYPHDVKGQ
     GIYAFVINPN VHNDEDLTRK DILQTVTRVI GAIAKPDKIL FVSGLPKTRS GKIMRRILRK
     IAEGETSQIG DTSTLLDPAV VTEIIEKAGQ LK
//