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C6XT77 (C6XT77_PEDHD) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase HAMAP MF_00061
Short name=CMK HAMAP MF_00061
EC=2.7.1.148 HAMAP MF_00061
Alternative name(s):
4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase HAMAP MF_00061
Gene names
Name:ispE HAMAP MF_00061
Ordered Locus Names:Phep_1424
OrganismPedobacter heparinus (strain ATCC 13125 / DSM 2366 / NCIB 9290) [Complete proteome] [HAMAP]
Taxonomic identifier485917 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Sphingobacteriia › Sphingobacteriales › Sphingobacteriaceae › Pedobacter

Protein attributes

Sequence length267 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol By similarity. HAMAP MF_00061

Catalytic activity

ATP + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol = ADP + 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol. HAMAP MF_00061

Pathway

Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 3/6. HAMAP MF_00061

Sequence similarities

Belongs to the GHMP kinase family. IspE subfamily. HAMAP MF_00061

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding90 – 10011ATP By similarity HAMAP MF_00061

Sites

Active site81 By similarity HAMAP MF_00061
Active site1321 By similarity HAMAP MF_00061

Sequences

Sequence LengthMass (Da)Tools
C6XT77 [UniParc].

Last modified September 22, 2009. Version 1.
Checksum: 8256E1FAF169DF0C

FASTA26729,510
        10         20         30         40         50         60 
MLAFANAKIN LGLNVTRKRP DGYHDIETVF YPVKLNDVVE ITDSENTICL VKGIDVPGDT 

        70         80         90        100        110        120 
RDNLCLKAFN LLKKDFDLPA QQITLLKNIP VGAGLGGGSS DAAQLIRLVN DKFKLGLSVV 

       130        140        150        160        170        180 
KMQNYARELG ADCAFFIENR PVYAFGKGDE FQPIAIDLSN YYVVLVKPPV HVSTAAAYAG 

       190        200        210        220        230        240 
IKPVIPSRSV KDLIHLPLKT WKQHLENDFE STVFSKYPEI ELVKKKLYQS GALFALMSGS 

       250        260 
GASVFAIFEH EVSLPELENG NKVFYNI

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001681 Genomic DNA. Translation: ACU03638.1.
RefSeqYP_003091700.1. NC_013061.1.

3D structure databases

ProteinModelPortalC6XT77.
ModBaseSearch...

Protein-protein interaction databases

STRINGC6XT77.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID8252524.
GenomeReviewsGene locus Phep_1424 in contig CP001681_GR.
KEGGphe:Phep_1424.
PATRIC22879923. VBIPedHep98714_1445.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAVSTAEVY.
ProtClustDBPRK14609.

Family and domain databases

HAMAPMF_00061. IspE.
[Tree]
InterProIPR006204. GHMP_kinase.
IPR013750. GHMP_kinase_C.
IPR004424. IspE.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
[Graphical view]
Gene3DG3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit.
KOK00919.
PANTHERPTHR20861:SF2. IspE. 1 hit.
PfamPF08544. GHMP_kinases_C. 1 hit.
PF00288. GHMP_kinases_N. 1 hit.
[Graphical view]
PIRSFPIRSF010376. IspE. 1 hit.
SUPFAMSSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
TIGRFAMsTIGR00154. IspE. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC6XT77_PEDHD
AccessionPrimary (citable) accession number: C6XT77
Entry history
Integrated into UniProtKB/TrEMBL: September 22, 2009
Last sequence update: September 22, 2009
Last modified: December 14, 2011
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info