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C6XJ10 (C6XJ10_HIRBI) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO HAMAP-Rule MF_01037

EC=2.1.1.74 HAMAP-Rule MF_01037
Alternative name(s):
Folate-dependent tRNA (uracil-5-)-methyltransferase HAMAP-Rule MF_01037
Folate-dependent tRNA(M-5-U54)-methyltransferase HAMAP-Rule MF_01037
Gene names
Name:trmFO HAMAP-Rule MF_01037
Ordered Locus Names:Hbal_1414 EMBL ACT59105.1
OrganismHirschia baltica (strain ATCC 49814 / DSM 5838 / IFAM 1418) [Complete proteome] [HAMAP] EMBL ACT59105.1
Taxonomic identifier582402 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesHyphomonadaceaeHirschia

Protein attributes

Sequence length473 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs By similarity. HAMAP-Rule MF_01037

Catalytic activity

5,10-methylenetetrahydrofolate + uracil54 in tRNA + FADH2 = tetrahydrofolate + 5-methyluracil54 in tRNA + FAD. HAMAP-Rule MF_01037 SAAS SAAS004417

Cofactor

FAD By similarity. HAMAP-Rule MF_01037 SAAS SAAS004417

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_01037 SAAS SAAS004417.

Sequence similarities

Belongs to the MnmG family. TrmFO subfamily. HAMAP-Rule MF_01037

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding21 – 266FAD By similarity HAMAP-Rule MF_01037

Sequences

Sequence LengthMass (Da)Tools
C6XJ10 [UniParc].

Last modified September 22, 2009. Version 1.
Checksum: E7CC48318D4ADC3A

FASTA47351,831
        10         20         30         40         50         60 
MTQLDNDANQ KSTLAPIHVI GGGMAGCEAA WQAANLGVPV ILHEMRPTKK TEAHQTDGLA 

        70         80         90        100        110        120 
ELVCSNSFRS DDFENNAVGL LHEEMRRANG LIISTAHDHQ IPAGSALAVD RDGFSQAVTA 

       130        140        150        160        170        180 
KIQAHPLITI EREEVPGIPP AEWDSVIIAT GPLTSPSMGE AIKELTGEDE LSFFDAIAPI 

       190        200        210        220        230        240 
VYYDSIDMSK AWRQSRYDKP GPSGETDAYV NCPMNEEQYL AFLEALNNAP KTEFKEWEKD 

       250        260        270        280        290        300 
TPYFEGCLPV EVMASRGPET LRYGPLKPVG LTNAHQPDVK AHAIVQLRQD NKLGTLWNIV 

       310        320        330        340        350        360 
GFQTKMTYGA QKDVLRMIPG LENAEFARLG GIHRNTFINS PKVLNNKLQL KNQLRIRFAG 

       370        380        390        400        410        420 
QVSGVEGYVE SAAMGLLAGR FAAFERLGRE ISPPPETTAL GSLISHVTGG HLIGKATFQP 

       430        440        450        460        470 
MNVNFGLFPD IDFAKADPET GKRYRGKDKS RAKKRAQSAR ALKDIQEWLG TQS 

« Hide

References

[1]"Genome sequences of eight morphologically diverse alphaproteobacteria."
US DOE Joint Genome Institute
Brown P.J., Kysela D.T., Buechlein A., Hemmerich C., Brun Y.V.
J. Bacteriol. 193:4567-4568(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 49814 / DSM 5838 / IFAM 1418.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001678 Genomic DNA. Translation: ACT59105.1.
RefSeqYP_003059802.1. NC_012982.1.

3D structure databases

ProteinModelPortalC6XJ10.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING582402.Hbal_1414.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACT59105; ACT59105; Hbal_1414.
GeneID8185977.
KEGGhba:Hbal_1414.
PATRIC22130848. VBIHirBal9878_1456.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1206.
HOGENOMHOG000252054.
KOK04094.
OMARFAGQIT.
OrthoDBEOG6J74VT.
ProtClustDBPRK05335.

Enzyme and pathway databases

BioCycHBAL582402:GHMV-1432-MONOMER.

Family and domain databases

HAMAPMF_01037. TrmFO.
InterProIPR004417. Folate-dep_Ribothymidyl_synth.
IPR002218. GIDA-rel.
[Graphical view]
PfamPF01134. GIDA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00137. gid_trmFO. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC6XJ10_HIRBI
AccessionPrimary (citable) accession number: C6XJ10
Entry history
Integrated into UniProtKB/TrEMBL: September 22, 2009
Last sequence update: September 22, 2009
Last modified: April 16, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)