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C6XGZ9 (C6XGZ9_LIBAP) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047
EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047 EMBL ACT57652.1
Ordered Locus Names:CLIBASIA_05430
OrganismLiberibacter asiaticus (strain psy62) [Complete proteome] [HAMAP]
Taxonomic identifier537021 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Candidatus Liberibacter ›

Protein attributes

Sequence length300 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS005905

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS005905

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS005905

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS005905.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047 SAAS SAAS005905

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain97 – 294198ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding124 – 17855ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2471Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2611Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2611Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding2631Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
C6XGZ9 [UniParc].

Last modified September 22, 2009. Version 1.
Checksum: 621B3E57E7FC8765

FASTA30032,768
        10         20         30         40         50         60 
MAVLMGGISS EREVSLSSGK ACASALEDAG FKVSQIDVDR SVGLVLAHLK PDLAFNVLHG 

        70         80         90        100        110        120 
NFGEDGLVQA ILELLEIPYT HSGILASALS MDKMRSKQVV SSCGVPVCPS ILVNRFTMDS 

       130        140        150        160        170        180 
QHLISPPYVI KPLKGGSSLG IIVIKKDQSI PLDLLQSSSW NHGDQLLIEQ YVDGIELTCG 

       190        200        210        220        230        240 
VMGDASLDVT EIAVPKSDFY SYELKYSSLN STHVLPAKIP LDIYKEVQRL AFLAHQAIGC 

       250        260        270        280        290        300 
RGISRSDFLF DPLSRKVFWL EINVQPGMTP VSIFPEMAAY AGYSFRELLL WMVEDASCLR

« Hide

References

[1]"Complete genome sequence of citrus huanglongbing bacterium, 'Candidatus Liberibacter asiaticus' obtained through metagenomics."
Duan Y., Zhou L., Hall D.G., Li W., Doddapaneni H., Lin H., Liu L., Vahling C.M., Gabriel D.W., Williams K.P., Dickerman A., Sun Y., Gottwald T.
Mol. Plant Microbe Interact. 22:1011-1020(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: psy62.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001677 Genomic DNA. Translation: ACT57652.1.
RefSeqYP_003065592.1. NC_012985.3.

3D structure databases

ProteinModelPortalC6XGZ9.
ModBaseSearch...

Protein-protein interaction databases

STRING537021.CLIBASIA_05430.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACT57652; ACT57652; CLIBASIA_05430.
GeneID8210204.
KEGGlas:CLIBASIA_05430.
PATRIC31989346. VBICanLib64949_1117.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1181.
HOGENOMHOG000011592.
KOK01921.
OMAWREAARY.

Enzyme and pathway databases

BioCycLASI537021:GHEM-1113-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 2 hits.
[Graphical view]
SUPFAMSSF52440. PreATP-grasp-like. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC6XGZ9_LIBAP
AccessionPrimary (citable) accession number: C6XGZ9
Entry history
Integrated into UniProtKB/TrEMBL: September 22, 2009
Last sequence update: September 22, 2009
Last modified: May 1, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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