C6XF74 (C6XF74_LIBAP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Holliday junction ATP-dependent DNA helicase RuvA HAMAP-Rule MF_00031
EC=3.6.4.12 HAMAP-Rule MF_00031

Gene names

Name:	ruvA HAMAP-Rule MF_00031 EMBL ACT57026.1
Ordered Locus Names:	CLIBASIA_02200 EMBL ACT57026.1

Organism

Liberibacter asiaticus (strain psy62) [Complete proteome] [HAMAP] EMBL ACT57026.1

Taxonomic identifier

537021 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Candidatus Liberibacter › Liberibacter asiaticus

Protein attributes

Sequence length	207 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB By similarity. HAMAP-Rule MF_00031
Catalytic activity	ATP + H2O = ADP + phosphate. HAMAP-Rule MF_00031 SAAS SAAS011114
Subunit structure	Forms a complex with RuvB By similarity. HAMAP-Rule MF_00031
Sequence similarities	Belongs to the RuvA family. HAMAP-Rule MF_00031

Ontologies

Keywords
Biological process	DNA damage DNA recombination HAMAP-Rule MF_00031 SAAS SAAS011114 DNA repair SOS response HAMAP-Rule MF_00031 SAAS SAAS011114
Ligand	ATP-binding DNA-binding HAMAP-Rule MF_00031 SAAS SAAS011114 Nucleotide-binding
Molecular function	Helicase HAMAP-Rule MF_00031 SAAS SAAS011114 EMBL ACT57026.1 Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	DNA duplex unwinding Inferred from electronic annotation. Source: GOC DNA recombination Inferred from electronic annotation. Source: UniProtKB-KW DNA repair Inferred from electronic annotation. Source: UniProtKB-KW SOS response Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	Holliday junction helicase complex Inferred from electronic annotation. Source: InterPro
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA binding Inferred from electronic annotation. Source: UniProtKB-KW four-way junction helicase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C6XF74 [UniParc]. Last modified September 22, 2009. Version 1. Checksum: 3567EF9BB9066D4E	FASTA	207	22,737
	10 20 30 40 50 60 MIGKIKGNIE GLYEDYVLID VQGVCYIIYC PIRTLSCLGK IGDFCTLFVE THMRQDQIRL 70 80 90 100 110 120 FGFLSDLDRQ WFMLLQSVQG VGARVAMGVL SRITATELVE SIILQNSKVI AQIPGISMKI 130 140 150 160 170 180 ASRIMTELKG KAISLSSVVQ QDMSCVNKEQ AHICSMPSFA INAISALVNL GYGQDQATTA 190 200 VVSVLKKEKN IADDSQIIRL ALRAISC

References

[1]

"Complete genome sequence of citrus huanglongbing bacterium, 'Candidatus Liberibacter asiaticus' obtained through metagenomics." Duan Y., Zhou L., Hall D.G., Li W., Doddapaneni H., Lin H., Liu L., Vahling C.M., Gabriel D.W., Williams K.P., Dickerman A., Sun Y., Gottwald T. Mol. Plant Microbe Interact. 22:1011-1020(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: psy62.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001677 Genomic DNA. Translation: ACT57026.1.
RefSeq	YP_003064966.1. NC_012985.3.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	537021.CLIBASIA_02200.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACT57026; ACT57026; CLIBASIA_02200.
GeneID	8209549.
KEGG	las:CLIBASIA_02200.
PATRIC	31988452. VBICanLib64949_0693.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0632.
HOGENOM	HOG000057115.
KO	K03550.
OMA	EATIFTH.
Enzyme and pathway databases
BioCyc	LASI537021:GHEM-680-MONOMER.
Family and domain databases
Gene3D	2.40.50.140. 1 hit.
HAMAP	MF_00031. DNA_helic_RuvA.
InterPro	IPR011114. DNA_helicas_Holl-junc_RuvA_C. IPR013849. DNA_helicase_Holl-junc_RuvA_I. IPR012340. NA-bd_OB-fold. IPR000085. RuvA. IPR010994. RuvA_2-like. [Graphical view]
Pfam	PF07499. RuvA_C. 1 hit. PF01330. RuvA_N. 1 hit. [Graphical view]
SUPFAM	SSF50249. Nucleic_acid_OB. 1 hit. SSF47781. RuvA_2_like. 1 hit. SSF46929. RuvA_C-like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C6XF74_LIBAP

Accession

Primary (citable) accession number: C6XF74

Entry history

Integrated into UniProtKB/TrEMBL:	September 22, 2009
Last sequence update:	September 22, 2009
Last modified:	May 29, 2013
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)