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C6XF74

- C6XF74_LIBAP

UniProt

C6XF74 - C6XF74_LIBAP

Protein

Holliday junction ATP-dependent DNA helicase RuvA

Gene

ruvA

Organism
Liberibacter asiaticus (strain psy62)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 30 (01 Oct 2014)
      Sequence version 1 (22 Sep 2009)
      Previous versions | rss
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    Functioni

    The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.UniRule annotation

    Catalytic activityi

    ATP + H2O = ADP + phosphate.UniRule annotationSAAS annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: UniProtKB-KW
    3. four-way junction helicase activity Source: InterPro

    GO - Biological processi

    1. DNA recombination Source: UniProtKB-KW
    2. DNA repair Source: UniProtKB-KW
    3. SOS response Source: UniProtKB-KW

    Keywords - Molecular functioni

    HelicaseUniRule annotationSAAS annotationImported, Hydrolase

    Keywords - Biological processi

    DNA damage, DNA recombinationUniRule annotationSAAS annotation, DNA repair, SOS responseUniRule annotationSAAS annotation

    Keywords - Ligandi

    ATP-binding, DNA-bindingUniRule annotationSAAS annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciLASI537021:GHEM-680-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Holliday junction ATP-dependent DNA helicase RuvAUniRule annotation (EC:3.6.4.12UniRule annotation)
    Gene namesi
    Name:ruvAUniRule annotationImported
    Ordered Locus Names:CLIBASIA_02200Imported
    OrganismiLiberibacter asiaticus (strain psy62)Imported
    Taxonomic identifieri537021 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeCandidatus Liberibacter
    ProteomesiUP000002744: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. Holliday junction helicase complex Source: InterPro

    Interactioni

    Subunit structurei

    Forms a complex with RuvB.UniRule annotation

    Protein-protein interaction databases

    STRINGi537021.CLIBASIA_02200.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the RuvA family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0632.
    HOGENOMiHOG000057115.
    KOiK03550.
    OMAiMRIYHES.
    OrthoDBiEOG679THG.

    Family and domain databases

    Gene3Di2.40.50.140. 1 hit.
    HAMAPiMF_00031. DNA_helic_RuvA.
    InterProiIPR011114. DNA_helicas_Holl-junc_RuvA_C.
    IPR013849. DNA_helicase_Holl-junc_RuvA_I.
    IPR012340. NA-bd_OB-fold.
    IPR000085. RuvA.
    IPR010994. RuvA_2-like.
    [Graphical view]
    PfamiPF07499. RuvA_C. 1 hit.
    PF01330. RuvA_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF46929. SSF46929. 1 hit.
    SSF47781. SSF47781. 1 hit.
    SSF50249. SSF50249. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    C6XF74-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIGKIKGNIE GLYEDYVLID VQGVCYIIYC PIRTLSCLGK IGDFCTLFVE    50
    THMRQDQIRL FGFLSDLDRQ WFMLLQSVQG VGARVAMGVL SRITATELVE 100
    SIILQNSKVI AQIPGISMKI ASRIMTELKG KAISLSSVVQ QDMSCVNKEQ 150
    AHICSMPSFA INAISALVNL GYGQDQATTA VVSVLKKEKN IADDSQIIRL 200
    ALRAISC 207
    Length:207
    Mass (Da):22,737
    Last modified:September 22, 2009 - v1
    Checksum:i3567EF9BB9066D4E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001677 Genomic DNA. Translation: ACT57026.1.
    RefSeqiYP_003064966.1. NC_012985.3.

    Genome annotation databases

    EnsemblBacteriaiACT57026; ACT57026; CLIBASIA_02200.
    GeneIDi8209549.
    KEGGilas:CLIBASIA_02200.
    PATRICi31988452. VBICanLib64949_0693.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001677 Genomic DNA. Translation: ACT57026.1 .
    RefSeqi YP_003064966.1. NC_012985.3.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 537021.CLIBASIA_02200.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACT57026 ; ACT57026 ; CLIBASIA_02200 .
    GeneIDi 8209549.
    KEGGi las:CLIBASIA_02200.
    PATRICi 31988452. VBICanLib64949_0693.

    Phylogenomic databases

    eggNOGi COG0632.
    HOGENOMi HOG000057115.
    KOi K03550.
    OMAi MRIYHES.
    OrthoDBi EOG679THG.

    Enzyme and pathway databases

    BioCyci LASI537021:GHEM-680-MONOMER.

    Family and domain databases

    Gene3Di 2.40.50.140. 1 hit.
    HAMAPi MF_00031. DNA_helic_RuvA.
    InterProi IPR011114. DNA_helicas_Holl-junc_RuvA_C.
    IPR013849. DNA_helicase_Holl-junc_RuvA_I.
    IPR012340. NA-bd_OB-fold.
    IPR000085. RuvA.
    IPR010994. RuvA_2-like.
    [Graphical view ]
    Pfami PF07499. RuvA_C. 1 hit.
    PF01330. RuvA_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46929. SSF46929. 1 hit.
    SSF47781. SSF47781. 1 hit.
    SSF50249. SSF50249. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of citrus huanglongbing bacterium, 'Candidatus Liberibacter asiaticus' obtained through metagenomics."
      Duan Y., Zhou L., Hall D.G., Li W., Doddapaneni H., Lin H., Liu L., Vahling C.M., Gabriel D.W., Williams K.P., Dickerman A., Sun Y., Gottwald T.
      Mol. Plant Microbe Interact. 22:1011-1020(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Psy62Imported.
    2. "Diversity and plasticity of the intracellular plant pathogen and insect symbiont, 'Candidatus Liberibacter asiaticus', revealed by hyper variable prophage genes with intragenic tandem repeats."
      Zhou L., Powell C.A., Hoffman M.T., Li W., Fan G., Liu B., Lin H., Duan Y.
      Appl. Environ. Microbiol. 77:6663-6673(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: psy62Imported.

    Entry informationi

    Entry nameiC6XF74_LIBAP
    AccessioniPrimary (citable) accession number: C6XF74
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 22, 2009
    Last sequence update: September 22, 2009
    Last modified: October 1, 2014
    This is version 30 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3