Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

C6X8R6

- C6X8R6_METGS

UniProt

C6X8R6 - C6X8R6_METGS

Protein

Elongation factor Tu

Gene

tuf

Organism
Methylovorus glucosetrophus (strain SIP3-4)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 40 (01 Oct 2014)
      Sequence version 1 (22 Sep 2009)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi19 – 268GTPUniRule annotation
    Nucleotide bindingi81 – 855GTPUniRule annotation
    Nucleotide bindingi136 – 1394GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-HAMAP
    3. translation elongation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Elongation factorUniRule annotationImported

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciMGLU582744:GHXQ-300-MONOMER.
    MGLU582744:GHXQ-313-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tufUniRule annotation
    Ordered Locus Names:Msip34_0287Imported, Msip34_0299Imported
    OrganismiMethylovorus glucosetrophus (strain SIP3-4)Imported
    Taxonomic identifieri582744 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaMethylophilalesMethylophilaceaeMethylovorus
    ProteomesiUP000002743: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi582744.Msip34_0299.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.UniRule annotation
    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0050.
    KOiK02358.
    OMAiGTEMCMP.
    OrthoDBiEOG6R5C6X.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. EFACTOR_GTP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C6X8R6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAKGKFERTK PHVNVGTIGH VDHGKTTLTA AITTILSKKF GGEAKAYDQI    50
    DAAPEEKARG ITINTAHVEY ETATRHYAHV DCPGHADYVK NMITGAAQMD 100
    GAILVCSAAD GPMPQTREHI LLARQVGVPY IVVFMNKADM VDDAELLELV 150
    EMEIRELLSK YDFPGDDIPV IKGSALKALE GDQSEIGEPA IFRLADALDS 200
    YIPTPERAVD GTFLMPVEDV FSISGRGTVV TGRIERGIVK VGDEIEIVGI 250
    KPTLKTTCTG VEMFRKLLDQ GQAGDNVGVL LRGTKREEVE RGQVLAKTGS 300
    IKPHTKFSAE IYVLGKDEGG RHTPFFNGYR PQFYFRTTDV TGAVELPAGT 350
    EMVMPGDNVS ITVALIAPIA MEDGLRFAIR EGGRTVGAGV VAKIIE 396
    Length:396
    Mass (Da):42,781
    Last modified:September 22, 2009 - v1
    Checksum:i6235B4D6F15BE665
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001674 Genomic DNA. Translation: ACT49536.1.
    CP001674 Genomic DNA. Translation: ACT49548.1.
    RefSeqiYP_003050063.1. NC_012969.1.
    YP_003050075.1. NC_012969.1.

    Genome annotation databases

    EnsemblBacteriaiACT49536; ACT49536; Msip34_0287.
    ACT49548; ACT49548; Msip34_0299.
    GeneIDi8173796.
    8173809.
    KEGGimei:Msip34_0287.
    mei:Msip34_0299.
    PATRICi22615556. VBIMetSp110381_0289.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001674 Genomic DNA. Translation: ACT49536.1 .
    CP001674 Genomic DNA. Translation: ACT49548.1 .
    RefSeqi YP_003050063.1. NC_012969.1.
    YP_003050075.1. NC_012969.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 582744.Msip34_0299.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACT49536 ; ACT49536 ; Msip34_0287 .
    ACT49548 ; ACT49548 ; Msip34_0299 .
    GeneIDi 8173796.
    8173809.
    KEGGi mei:Msip34_0287.
    mei:Msip34_0299.
    PATRICi 22615556. VBIMetSp110381_0289.

    Phylogenomic databases

    eggNOGi COG0050.
    KOi K02358.
    OMAi GTEMCMP.
    OrthoDBi EOG6R5C6X.

    Enzyme and pathway databases

    BioCyci MGLU582744:GHXQ-300-MONOMER.
    MGLU582744:GHXQ-313-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. EFACTOR_GTP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of chromosome of Methylovorus sp. SIP3-4."
      Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Clum A., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Kayluzhnaya M., Chistoserdova L.
      Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SIP3-4Imported.
    2. "Genomes of three methylotrophs from a single niche reveal the genetic and metabolic divergence of the methylophilaceae."
      Lapidus A., Clum A., Labutti K., Kaluzhnaya M.G., Lim S., Beck D.A., Glavina Del Rio T., Nolan M., Mavromatis K., Huntemann M., Lucas S., Lidstrom M.E., Ivanova N., Chistoserdova L.
      J. Bacteriol. 193:3757-3764(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: SIP3-4Imported.

    Entry informationi

    Entry nameiC6X8R6_METGS
    AccessioniPrimary (citable) accession number: C6X8R6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 22, 2009
    Last sequence update: September 22, 2009
    Last modified: October 1, 2014
    This is version 40 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3