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Protein

Elongation factor Tu

Gene

tuf

Organism
Methylovorus glucosetrophus (strain SIP3-4)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi19 – 26GTPUniRule annotation8
Nucleotide bindingi81 – 85GTPUniRule annotation5
Nucleotide bindingi136 – 139GTPUniRule annotation4

GO - Molecular functioni

Keywordsi

Molecular functionElongation factorUniRule annotationImported
Biological processProtein biosynthesis
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tufUniRule annotation
Ordered Locus Names:Msip34_0287Imported, Msip34_0299Imported
OrganismiMethylovorus glucosetrophus (strain SIP3-4)Imported
Taxonomic identifieri582744 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNitrosomonadalesMethylophilaceaeMethylovorus
Proteomesi
  • UP000002743 Componenti: Chromosome

Subcellular locationi

C6X8R6:
  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi582744.Msip34_0299.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 206Tr-type GInterPro annotationAdd BLAST197

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CGV. Bacteria.
COG0050. LUCA.
KOiK02358.
OMAiYGHIDCP.
OrthoDBiPOG091H00LA.

Family and domain databases

CDDicd03697. EFTU_II. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B. 1 hit.
InterProiView protein in InterPro
IPR004161. EFTu-like_2.
IPR033720. EFTU_2.
IPR031157. G_TR_CS.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
PfamiView protein in Pfam
PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiView protein in PROSITE
PS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.

Sequencei

Sequence statusi: Complete.

C6X8R6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKGKFERTK PHVNVGTIGH VDHGKTTLTA AITTILSKKF GGEAKAYDQI
60 70 80 90 100
DAAPEEKARG ITINTAHVEY ETATRHYAHV DCPGHADYVK NMITGAAQMD
110 120 130 140 150
GAILVCSAAD GPMPQTREHI LLARQVGVPY IVVFMNKADM VDDAELLELV
160 170 180 190 200
EMEIRELLSK YDFPGDDIPV IKGSALKALE GDQSEIGEPA IFRLADALDS
210 220 230 240 250
YIPTPERAVD GTFLMPVEDV FSISGRGTVV TGRIERGIVK VGDEIEIVGI
260 270 280 290 300
KPTLKTTCTG VEMFRKLLDQ GQAGDNVGVL LRGTKREEVE RGQVLAKTGS
310 320 330 340 350
IKPHTKFSAE IYVLGKDEGG RHTPFFNGYR PQFYFRTTDV TGAVELPAGT
360 370 380 390
EMVMPGDNVS ITVALIAPIA MEDGLRFAIR EGGRTVGAGV VAKIIE
Length:396
Mass (Da):42,781
Last modified:September 22, 2009 - v1
Checksum:i6235B4D6F15BE665
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001674 Genomic DNA. Translation: ACT49536.1.
CP001674 Genomic DNA. Translation: ACT49548.1.
RefSeqiWP_013441116.1. NC_012969.1.

Genome annotation databases

EnsemblBacteriaiACT49536; ACT49536; Msip34_0287.
ACT49548; ACT49548; Msip34_0299.
KEGGimei:Msip34_0287.
mei:Msip34_0299.

Similar proteinsi

Entry informationi

Entry nameiC6X8R6_METGS
AccessioniPrimary (citable) accession number: C6X8R6
Entry historyiIntegrated into UniProtKB/TrEMBL: September 22, 2009
Last sequence update: September 22, 2009
Last modified: September 27, 2017
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported