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C6WTB9

- C6WTB9_METML

UniProt

C6WTB9 - C6WTB9_METML

Protein

Elongation factor Tu

Gene

tuf

Organism
Methylotenera mobilis (strain JLW8 / ATCC BAA-1282 / DSM 17540)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 39 (01 Oct 2014)
      Sequence version 1 (22 Sep 2009)
      Previous versions | rss
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    Functioni

    This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi19 – 268GTPUniRule annotation
    Nucleotide bindingi81 – 855GTPUniRule annotation
    Nucleotide bindingi136 – 1394GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-HAMAP
    3. translation elongation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Elongation factorUniRule annotationImported

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciMMOB583345:GHCF-345-MONOMER.
    MMOB583345:GHCF-358-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tufUniRule annotation
    Ordered Locus Names:Mmol_0331Imported, Mmol_0343Imported
    OrganismiMethylotenera mobilis (strain JLW8 / ATCC BAA-1282 / DSM 17540)Imported
    Taxonomic identifieri583345 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaMethylophilalesMethylophilaceaeMethylotenera
    ProteomesiUP000002742: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi583345.Mmol_0343.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.UniRule annotation
    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0050.
    HOGENOMiHOG000229290.
    KOiK02358.
    OMAiGTEMCMP.
    OrthoDBiEOG6R5C6X.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. EFACTOR_GTP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C6WTB9-1 [UniParc]FASTAAdd to Basket

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    MAKGKFERTK PHVNVGTIGH VDHGKTTLTA AITTVLTKKF GGEAKAYDQI    50
    DAAPEEKARG ITINTAHVEY ETANRHYAHV DCPGHADYVK NMITGAAQMD 100
    GAILVCSAAD GPMPQTREHI LLARQVGVPY IVVFLNKADM VDDAELLELV 150
    EMEVRDLLSK YDFPGDDTPI VKGSAKLALE GDQSPIGEPA IFALADALDS 200
    YIPMPERAVD GTFLMPVEDV FSISGRGTVV TGRIERGIVK VGDEIEIVGL 250
    KDTLKTTCTG VEMFRKLLDQ GMAGDNVGVL LRGTKREEIE RGQVLAKAGS 300
    IKPHTKFTAE IYVLGKDEGG RHTPFFQGYR PQFYFRTTDV TGAVELPAGT 350
    EMVMPGDNVS ITVTLIAPIA MEEGLRFAIR EGGRTVGAGV VAKIIE 396
    Length:396
    Mass (Da):42,726
    Last modified:September 22, 2009 - v1
    Checksum:i6E8D45477106F660
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001672 Genomic DNA. Translation: ACT47241.1.
    CP001672 Genomic DNA. Translation: ACT47253.1.
    RefSeqiYP_003047768.1. NC_012968.1.
    YP_003047780.1. NC_012968.1.

    Genome annotation databases

    EnsemblBacteriaiACT47241; ACT47241; Mmol_0331.
    ACT47253; ACT47253; Mmol_0343.
    GeneIDi8171433.
    8171446.
    KEGGimmb:Mmol_0331.
    mmb:Mmol_0343.
    PATRICi22610819. VBIMetMob89187_0336.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001672 Genomic DNA. Translation: ACT47241.1 .
    CP001672 Genomic DNA. Translation: ACT47253.1 .
    RefSeqi YP_003047768.1. NC_012968.1.
    YP_003047780.1. NC_012968.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 583345.Mmol_0343.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACT47241 ; ACT47241 ; Mmol_0331 .
    ACT47253 ; ACT47253 ; Mmol_0343 .
    GeneIDi 8171433.
    8171446.
    KEGGi mmb:Mmol_0331.
    mmb:Mmol_0343.
    PATRICi 22610819. VBIMetMob89187_0336.

    Phylogenomic databases

    eggNOGi COG0050.
    HOGENOMi HOG000229290.
    KOi K02358.
    OMAi GTEMCMP.
    OrthoDBi EOG6R5C6X.

    Enzyme and pathway databases

    BioCyci MMOB583345:GHCF-345-MONOMER.
    MMOB583345:GHCF-358-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. EFACTOR_GTP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: JLW8 / ATCC BAA-1282 / DSM 17540Imported.
    2. "Genomes of three methylotrophs from a single niche reveal the genetic and metabolic divergence of the methylophilaceae."
      Lapidus A., Clum A., Labutti K., Kaluzhnaya M.G., Lim S., Beck D.A., Glavina Del Rio T., Nolan M., Mavromatis K., Huntemann M., Lucas S., Lidstrom M.E., Ivanova N., Chistoserdova L.
      J. Bacteriol. 193:3757-3764(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: JLW8Imported.

    Entry informationi

    Entry nameiC6WTB9_METML
    AccessioniPrimary (citable) accession number: C6WTB9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 22, 2009
    Last sequence update: September 22, 2009
    Last modified: October 1, 2014
    This is version 39 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3