ID   C6WJP4_ACTMD            Unreviewed;       256 AA.
AC   C6WJP4;
DT   22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   22-SEP-2009, sequence version 1.
DT   27-MAR-2024, entry version 64.
DE   SubName: Full=Type III secretion system inner membrane R protein {ECO:0000313|EMBL:ACU36269.1};
GN   OrderedLocusNames=Amir_2329 {ECO:0000313|EMBL:ACU36269.1};
OS   Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / JCM 3225 / NBRC 14064
OS   / NCIMB 13271 / NRRL B-12336 / IMRU 3971 / 101).
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Actinosynnema.
OX   NCBI_TaxID=446462 {ECO:0000313|EMBL:ACU36269.1, ECO:0000313|Proteomes:UP000002213};
RN   [1] {ECO:0000313|EMBL:ACU36269.1, ECO:0000313|Proteomes:UP000002213}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29888 / DSM 43827 / JCM 3225 / NBRC 14064 / NCIMB 13271 /
RC   NRRL B-12336 / IMRU 3971 / 101 {ECO:0000313|Proteomes:UP000002213};
RX   PubMed=21304636; DOI=10.4056/sigs.21137;
RA   Land M., Lapidus A., Mayilraj S., Chen F., Copeland A., Del Rio T.G.,
RA   Nolan M., Lucas S., Tice H., Cheng J.F., Chertkov O., Bruce D., Goodwin L.,
RA   Pitluck S., Rohde M., Goker M., Pati A., Ivanova N., Mavromatis K.,
RA   Chen A., Palaniappan K., Hauser L., Chang Y.J., Jeffries C.C., Brettin T.,
RA   Detter J.C., Han C., Chain P., Tindall B.J., Bristow J., Eisen J.A.,
RA   Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT   "Complete genome sequence of Actinosynnema mirum type strain (101).";
RL   Stand. Genomic Sci. 1:46-53(2009).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the FliR/MopE/SpaR family.
CC       {ECO:0000256|ARBA:ARBA00009772}.
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DR   EMBL; CP001630; ACU36269.1; -; Genomic_DNA.
DR   RefSeq; WP_015801158.1; NC_013093.1.
DR   AlphaFoldDB; C6WJP4; -.
DR   STRING; 446462.Amir_2329; -.
DR   KEGG; ami:Amir_2329; -.
DR   eggNOG; COG1684; Bacteria.
DR   HOGENOM; CLU_063626_2_1_11; -.
DR   OrthoDB; 9807748at2; -.
DR   Proteomes; UP000002213; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006605; P:protein targeting; IEA:InterPro.
DR   InterPro; IPR002010; T3SS_IM_R.
DR   PANTHER; PTHR30065; FLAGELLAR BIOSYNTHETIC PROTEIN FLIR; 1.
DR   PANTHER; PTHR30065:SF1; SURFACE PRESENTATION OF ANTIGENS PROTEIN SPAR; 1.
DR   Pfam; PF01311; Bac_export_1; 1.
DR   PRINTS; PR00953; TYPE3IMRPROT.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002213};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        37..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        68..93
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        127..146
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        178..203
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        215..235
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   256 AA;  26182 MW;  85C4A3CB67652E0A CRC64;
     MNLDIGVNVL VALLLAATRS AAWLMVCPPF NGKAIPMTVK GMLAVGLALP VVPRLSAGSV
     PSLDTWSLVI AAGEQVVVGA GLGFLTAVIF AGVQAAGDLL DVFGGFSLAF AFDPMSFSGN
     NAVLGRFYGL LATTLLFVTG SHQVIIRGFT LSYDAIPLDG GLSLGRLGTL LTTGLGQLLL
     SAAQIAGPLI VVLFCADVGL GLLNRIAPAL NPFQIGFPAK IGLTLVLVGL TMPMLPMSVE
     NIAKHAASAV MEAIGR
//