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C6WGG0 (C6WGG0_ACTMD) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Inorganic pyrophosphatase HAMAP-Rule MF_00209
EC=3.6.1.1 HAMAP-Rule MF_00209
Alternative name(s):
Pyrophosphate phospho-hydrolase HAMAP-Rule MF_00209
Gene names
Name:ppa HAMAP-Rule MF_00209
Ordered Locus Names:Amir_0307
OrganismActinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971) [Complete proteome] [HAMAP]
Taxonomic identifier446462 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Pseudonocardineae › Pseudonocardiaceae › Actinosynnema ›

Protein attributes

Sequence length167 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Diphosphate + H2O = 2 phosphate. HAMAP-Rule MF_00209

Cofactor

Binds 4 magnesium ions per subunit. Other metal ions can support activity, but at a lower rate. Two magnesium ions are required for the activation of the enzyme and are present before substrate binds, two additional magnesium ions form complexes with substrate and product By similarity. HAMAP-Rule MF_00209

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00209.

Sequence similarities

Belongs to the PPase family. HAMAP-Rule MF_00209

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding521Magnesium 1 By similarity HAMAP-Rule MF_00209
Metal binding571Magnesium 1 By similarity HAMAP-Rule MF_00209
Metal binding571Magnesium 2 By similarity HAMAP-Rule MF_00209
Metal binding891Magnesium 1 By similarity HAMAP-Rule MF_00209

Sequences

Sequence LengthMass (Da)Tools
C6WGG0 [UniParc].

Last modified September 22, 2009. Version 1.
Checksum: 7F199103FC016CE2

FASTA16719,193
        10         20         30         40         50         60 
MEFDVTIEIP KGVRNKYEMD HKTGRIRLDR TLFTATQYPA DYGFVDDTLG EDGDPLDALV 

        70         80         90        100        110        120 
LVQEPTFPGC LIRCRAIGMF RMTDEKGGDD KLLCVPSDDP RSEHLRDIHH LSEFYRLEIQ 

       130        140        150        160 
HFFEVYKDLE PGKSVEGATW VGRTEAEAEI VRSYQRLKDA VARGEEH

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001630 Genomic DNA. Translation: ACU34276.1.
RefSeqYP_003098122.1. NC_013093.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRING446462.Amir_0307.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACU34276; ACU34276; Amir_0307.
GeneID8324465.
KEGGami:Amir_0307.
PATRIC20763375. VBIActMir80567_0314.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0221.
HOGENOMHOG000236473.
KOK01507.
OMAMFRMRDE.
ProtClustDBCLSK2535854.

Enzyme and pathway databases

BioCycAMIR446462:GH7R-322-MONOMER.

Family and domain databases

Gene3D3.90.80.10. 1 hit.
HAMAPMF_00209. Inorganic_PPase.
InterProIPR008162. Pyrophosphatase.
[Graphical view]
PANTHERPTHR10286. PTHR10286. 1 hit.
PfamPF00719. Pyrophosphatase. 1 hit.
[Graphical view]
SUPFAMSSF50324. Pyrophosphatase. 1 hit.
PROSITEPS00387. PPASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC6WGG0_ACTMD
AccessionPrimary (citable) accession number: C6WGG0
Entry history
Integrated into UniProtKB/TrEMBL: September 22, 2009
Last sequence update: September 22, 2009
Last modified: May 1, 2013
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info