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Protein

Xylose isomerase

Gene

xylA

Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei47UniRule annotation1
Active sitei50UniRule annotation1
Metal bindingi174Magnesium 1UniRule annotation1
Metal bindingi210Magnesium 1UniRule annotation1
Metal bindingi210Magnesium 2UniRule annotation1
Metal bindingi213Magnesium 2UniRule annotation1
Metal bindingi238Magnesium 1UniRule annotation1
Metal bindingi280Magnesium 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
Biological processCarbohydrate metabolism, Xylose metabolismUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotation, Metal-bindingUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciAMIR446462:G1GEY-1816-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotationSAAS annotation (EC:5.3.1.5UniRule annotationSAAS annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:Amir_1795Imported
OrganismiActinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)Imported
Taxonomic identifieri446462 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaPseudonocardialesPseudonocardiaceaeActinosynnema
Proteomesi
  • UP000002213 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi446462.Amir_1795

Structurei

3D structure databases

ProteinModelPortaliC6WCX6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 258AP_endonuc_2InterPro annotationAdd BLAST225

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105C93 Bacteria
COG2115 LUCA
HOGENOMiHOG000022596
KOiK01805
OMAiNQLAIEH
OrthoDBiPOG091H07LC

Family and domain databases

HAMAPiMF_00455 Xylose_isom_A, 1 hit
InterProiView protein in InterPro
IPR036237 Xyl_isomerase-like_sf
IPR013022 Xyl_isomerase-like_TIM-brl
IPR013453 XylA_actinobac
IPR001998 Xylose_isomerase
PANTHERiPTHR32176:SF0 PTHR32176:SF0, 1 hit
PfamiView protein in Pfam
PF01261 AP_endonuc_2, 1 hit
PRINTSiPR00688 XYLOSISMRASE
SUPFAMiSSF51658 SSF51658, 1 hit
TIGRFAMsiTIGR02631 xylA_Arthro, 1 hit
PROSITEiView protein in PROSITE
PS51415 XYLOSE_ISOMERASE, 1 hit

Sequencei

Sequence statusi: Complete.

C6WCX6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTDFSFGLWT VGWQGRDPFG DATRPVLDAP TAVRKLAELG AWGVTFHDDD
60 70 80 90 100
LIPFGAGAAE RDRRVSAFRG ALDETGLVVP MVTTNLFTHP VFKDGGFTSN
110 120 130 140 150
DRSVRRFALR KVLRNLELAA ELGAKTIVLW GGREGSETDA GKDVQAALER
160 170 180 190 200
YREALDTVAQ HSVDQGYGFR FALEPKPNEP RGDILLPTVG HALAFISTLQ
210 220 230 240 250
HHELVGVNPE VGHEQMANLN FVHGIAQALW QKKLFHIDLN GQKGPRFDQD
260 270 280 290 300
LVFGHGDLLS AFFLVDLLEN GGYDGPRHFD YKPLRTEDVD GVWDSAAANM
310 320 330 340 350
RTYTLLKERA QAYRADPEVQ EALRVSGVTE QAVPTLGEGE SIADFLAADE
360 370
SFDPDKAAER GYGFVKLSQL ALEHLLGAR
Length:379
Mass (Da):41,711
Last modified:September 22, 2009 - v1
Checksum:iFDF9C447C8617C62
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001630 Genomic DNA Translation: ACU35743.1
RefSeqiWP_015800632.1, NC_013093.1

Genome annotation databases

EnsemblBacteriaiACU35743; ACU35743; Amir_1795
KEGGiami:Amir_1795

Similar proteinsi

Entry informationi

Entry nameiC6WCX6_ACTMD
AccessioniPrimary (citable) accession number: C6WCX6
Entry historyiIntegrated into UniProtKB/TrEMBL: September 22, 2009
Last sequence update: September 22, 2009
Last modified: May 23, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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