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C6WCX6

- C6WCX6_ACTMD

UniProt

C6WCX6 - C6WCX6_ACTMD

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Protein
Xylose isomerase
Gene
xylA, Amir_1795
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotations

Cofactori

Binds 2 magnesium ions per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei47 – 471 By similarityUniRule annotation
Active sitei50 – 501 By similarityUniRule annotation
Metal bindingi174 – 1741Magnesium 1 By similarityUniRule annotation
Metal bindingi210 – 2101Magnesium 1 By similarityUniRule annotation
Metal bindingi210 – 2101Magnesium 2 By similarityUniRule annotation
Metal bindingi213 – 2131Magnesium 2 By similarityUniRule annotation
Metal bindingi238 – 2381Magnesium 1 By similarityUniRule annotation
Metal bindingi248 – 2481Magnesium 2 By similarityUniRule annotation
Metal bindingi250 – 2501Magnesium 2 By similarityUniRule annotation
Metal bindingi280 – 2801Magnesium 1 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. xylose isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-xylose metabolic process Source: UniProtKB-HAMAP
  2. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotationSAAS annotations, Xylose metabolismUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciAMIR446462:GH7R-1836-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:Amir_1795Imported
OrganismiActinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)Imported
Taxonomic identifieri446462 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesPseudonocardineaePseudonocardiaceaeActinosynnema
ProteomesiUP000002213: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi446462.Amir_1795.

Structurei

3D structure databases

ProteinModelPortaliC6WCX6.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG2115.
HOGENOMiHOG000022596.
KOiK01805.
OMAiFAHETMA.
OrthoDBiEOG62NX4R.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013453. XylA_actinobac.
IPR001998. Xylose_isomerase.
[Graphical view]
PfamiPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02631. xylA_Arthro. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C6WCX6-1 [UniParc]FASTAAdd to Basket

« Hide

MTDFSFGLWT VGWQGRDPFG DATRPVLDAP TAVRKLAELG AWGVTFHDDD    50
LIPFGAGAAE RDRRVSAFRG ALDETGLVVP MVTTNLFTHP VFKDGGFTSN 100
DRSVRRFALR KVLRNLELAA ELGAKTIVLW GGREGSETDA GKDVQAALER 150
YREALDTVAQ HSVDQGYGFR FALEPKPNEP RGDILLPTVG HALAFISTLQ 200
HHELVGVNPE VGHEQMANLN FVHGIAQALW QKKLFHIDLN GQKGPRFDQD 250
LVFGHGDLLS AFFLVDLLEN GGYDGPRHFD YKPLRTEDVD GVWDSAAANM 300
RTYTLLKERA QAYRADPEVQ EALRVSGVTE QAVPTLGEGE SIADFLAADE 350
SFDPDKAAER GYGFVKLSQL ALEHLLGAR 379
Length:379
Mass (Da):41,711
Last modified:September 22, 2009 - v1
Checksum:iFDF9C447C8617C62
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001630 Genomic DNA. Translation: ACU35743.1.
RefSeqiYP_003099589.1. NC_013093.1.

Genome annotation databases

EnsemblBacteriaiACU35743; ACU35743; Amir_1795.
GeneIDi8325980.
KEGGiami:Amir_1795.
PATRICi20766471. VBIActMir80567_1848.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001630 Genomic DNA. Translation: ACU35743.1 .
RefSeqi YP_003099589.1. NC_013093.1.

3D structure databases

ProteinModelPortali C6WCX6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 446462.Amir_1795.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACU35743 ; ACU35743 ; Amir_1795 .
GeneIDi 8325980.
KEGGi ami:Amir_1795.
PATRICi 20766471. VBIActMir80567_1848.

Phylogenomic databases

eggNOGi COG2115.
HOGENOMi HOG000022596.
KOi K01805.
OMAi FAHETMA.
OrthoDBi EOG62NX4R.

Enzyme and pathway databases

BioCyci AMIR446462:GH7R-1836-MONOMER.

Family and domain databases

Gene3Di 3.20.20.150. 1 hit.
HAMAPi MF_00455. Xylose_isom_A.
InterProi IPR013022. Xyl_isomerase-like_TIM-brl.
IPR013453. XylA_actinobac.
IPR001998. Xylose_isomerase.
[Graphical view ]
Pfami PF01261. AP_endonuc_2. 1 hit.
[Graphical view ]
PRINTSi PR00688. XYLOSISMRASE.
SUPFAMi SSF51658. SSF51658. 1 hit.
TIGRFAMsi TIGR02631. xylA_Arthro. 1 hit.
PROSITEi PS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971.

Entry informationi

Entry nameiC6WCX6_ACTMD
AccessioniPrimary (citable) accession number: C6WCX6
Entry historyi
Integrated into UniProtKB/TrEMBL: September 22, 2009
Last sequence update: September 22, 2009
Last modified: June 11, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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