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C6W9I3 (C6W9I3_ACTMD) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
6-phosphofructokinase HAMAP-Rule MF_00339

Short name=Phosphofructokinase HAMAP-Rule MF_00339
EC=2.7.1.11 HAMAP-Rule MF_00339
Alternative name(s):
Phosphohexokinase HAMAP-Rule MF_00339
Gene names
Name:pfkA HAMAP-Rule MF_00339
Ordered Locus Names:Amir_1394 EMBL ACU35346.1
OrganismActinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971) [Complete proteome] [HAMAP] EMBL ACU35346.1
Taxonomic identifier446462 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesPseudonocardineaePseudonocardiaceaeActinosynnema

Protein attributes

Sequence length346 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate. HAMAP-Rule MF_00339

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4. HAMAP-Rule MF_00339

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00339.

Sequence similarities

Belongs to the phosphofructokinase family. HAMAP-Rule MF_00339

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding25 – 295ATP By similarity HAMAP-Rule MF_00339
Nucleotide binding159 – 1635ATP By similarity HAMAP-Rule MF_00339
Nucleotide binding176 – 19217ATP By similarity HAMAP-Rule MF_00339

Sites

Active site1321Proton acceptor By similarity HAMAP-Rule MF_00339
Binding site1671Substrate By similarity HAMAP-Rule MF_00339
Binding site2701Substrate By similarity HAMAP-Rule MF_00339
Binding site2761Substrate By similarity HAMAP-Rule MF_00339
Binding site2791Substrate By similarity HAMAP-Rule MF_00339

Sequences

Sequence LengthMass (Da)Tools
C6W9I3 [UniParc].

Last modified September 22, 2009. Version 1.
Checksum: E51AF630BB55186A

FASTA34636,818
        10         20         30         40         50         60 
MGDEQMRIGV LTGGGDCPGL NAVIRGVVRK GVETHGWDVL GFRNGWQGPI EGLTKPIGLA 

        70         80         90        100        110        120 
DVEDILTRGG TILGSSRTNP YKVEGGVEAI RKTLKEHGVD ALIAIGGEDT LGVAKRLTDD 

       130        140        150        160        170        180 
GIGVVGVPKT IDNDLGATDY TFGFDTAVHI ATEAIDRLRT TAESHHRALV VEVMGRHAGW 

       190        200        210        220        230        240 
IALHSGLAGG ANVILVPERE FDVDQVVTWV ERRFEKQYAP IIVVAEGAIP QGGAEVLHSG 

       250        260        270        280        290        300 
EKDAFGHVRL GGVGTWLAEE IAQRTGKESR AVVLGHVQRG GIPTAYDRVL ATRFGLHAVD 

       310        320        330        340 
AVADGDFGVM VALKGTDIVR VKLSEATAEL KTVPLERYQE AEVFFG 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001630 Genomic DNA. Translation: ACU35346.1.
RefSeqYP_003099192.1. NC_013093.1.

3D structure databases

ProteinModelPortalC6W9I3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING446462.Amir_1394.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACU35346; ACU35346; Amir_1394.
GeneID8325574.
KEGGami:Amir_1394.
PATRIC20765615. VBIActMir80567_1421.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0205.
HOGENOMHOG000248869.
KOK00850.
OMAIPEIPYK.
OrthoDBEOG644ZRM.
ProtClustDBPRK03202.

Enzyme and pathway databases

BioCycAMIR446462:GH7R-1431-MONOMER.
UniPathwayUPA00109; UER00182.

Family and domain databases

HAMAPMF_00339. Phosphofructokinase.
InterProIPR012003. ATP_PFK_prok.
IPR012829. PFK.
IPR022953. Phosphofructokinase.
IPR015912. Phosphofructokinase_CS.
IPR000023. Phosphofructokinase_dom.
[Graphical view]
PfamPF00365. PFK. 1 hit.
[Graphical view]
PIRSFPIRSF000532. ATP_PFK_prok. 1 hit.
PRINTSPR00476. PHFRCTKINASE.
SUPFAMSSF53784. SSF53784. 1 hit.
TIGRFAMsTIGR02483. PFK_mixed. 1 hit.
PROSITEPS00433. PHOSPHOFRUCTOKINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC6W9I3_ACTMD
AccessionPrimary (citable) accession number: C6W9I3
Entry history
Integrated into UniProtKB/TrEMBL: September 22, 2009
Last sequence update: September 22, 2009
Last modified: April 16, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)