C6W8Y7 (C6W8Y7_ACTMD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Guanylate kinase EMBL ACU39059.1
EC=2.7.4.8 EMBL ACU39059.1

Gene names

Ordered Locus Names:

Amir_5238

Organism

Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971) [Complete proteome] [HAMAP]

Taxonomic identifier

446462 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Pseudonocardineae › Actinosynnemataceae › Actinosynnema

Protein attributes

Sequence length	199 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Essential for recycling GMP and indirectly, cGMP By similarity. SAAS SAAS020590
Catalytic activity	ATP + GMP = ADP + GDP. SAAS SAAS020590
Subcellular location	Cytoplasm By similarity SAAS SAAS020590.
Sequence similarities	Contains 1 guanylate kinase-like domain. SAAS SAAS017665

Ontologies

Keywords
Cellular component	Cytoplasm SAAS SAAS020590
Ligand	ATP-binding SAAS SAAS020590 Nucleotide-binding
Molecular function	Kinase SAAS SAAS020590 EMBL ACU39059.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	purine nucleotide metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW guanylate kinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C6W8Y7 [UniParc]. Last modified September 22, 2009. Version 1. Checksum: 4619DBC6FF6F09C7	FASTA	199	21,165
	10 20 30 40 50 60 MSDGTGAGSG VRARPRLTVL SGPSGVGKSS VLAELRGRDP ELHYSVSVTT RKPRPGELDG 70 80 90 100 110 120 VHYHFVDGAE FDRMVDAGEL LEHAEFAGNR YGTPRAPVEA ALASGLPSLL EIELQGARQV 130 140 150 160 170 180 RAAMPEARLV MLAPPSWEDL VARLTGRGTE DPAVVERRLA IARQELAAEP EFDEVVVNDD 190 VRSAATKLLD LVVGPLPGA

References

[1]

"Complete genome sequence of Actinosynnema mirum type strain (101)." Land M., Lapidus A., Mayilraj S., Chen F., Copeland A., Glavina del Rio T., Nolan M., Lucas S., Tice H., Cheng J.-F., Chertkov O., Bruce D., Goodwin L., Pitluck S., Rohde M., Goeker M., Pati A., Ivanova N. , Mavromatis K., Chen A., Palaniappan K., Hauser L., Chang Y.-J., Jeffries C.C., Brettin T., Detter J.C., Han C., Chain P., Tindall B.J., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.-P. Stand. Genomic Sci. 1:46-53(2009) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001630 Genomic DNA. Translation: ACU39059.1.
RefSeq	YP_003102905.1. NC_013093.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	C6W8Y7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8329440.
GenomeReviews	Gene locus Amir_5238 in contig CP001630_GR.
KEGG	ami:Amir_5238.
PATRIC	20773536. VBIActMir80567_5370.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	EWAEFAG.
Family and domain databases
HAMAP	MF_00328. Guanylate_kinase. [Tree]
InterPro	IPR008144. Guanylate_kin. IPR008145. Guanylate_kin/L-typ_Ca_channel. IPR020590. Guanylate_kinase_CS. IPR017665. Guanylate_kinase_sub. [Graphical view]
KO	K00942.
Pfam	PF00625. Guanylate_kin. 1 hit. [Graphical view]
SMART	SM00072. GuKc. 1 hit. [Graphical view]
TIGRFAMs	TIGR03263. Guanyl_kin. 1 hit.
PROSITE	PS00856. GUANYLATE_KINASE_1. 1 hit. PS50052. GUANYLATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C6W8Y7_ACTMD

Accession

Primary (citable) accession number: C6W8Y7

Entry history

Integrated into UniProtKB/TrEMBL:	September 22, 2009
Last sequence update:	September 22, 2009
Last modified:	December 14, 2011
This is version 14 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)