ID   C6W5L7_DYAFD            Unreviewed;       388 AA.
AC   C6W5L7;
DT   22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   22-SEP-2009, sequence version 1.
DT   27-MAR-2024, entry version 66.
DE   RecName: Full=exo-alpha-sialidase {ECO:0000256|ARBA:ARBA00012733};
DE            EC=3.2.1.18 {ECO:0000256|ARBA:ARBA00012733};
GN   OrderedLocusNames=Dfer_3020 {ECO:0000313|EMBL:ACT94235.1};
OS   Dyadobacter fermentans (strain ATCC 700827 / DSM 18053 / CIP 107007 /
OS   KCTC 52180 / NS114).
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Spirosomataceae;
OC   Dyadobacter.
OX   NCBI_TaxID=471854 {ECO:0000313|EMBL:ACT94235.1, ECO:0000313|Proteomes:UP000002011};
RN   [1] {ECO:0000313|EMBL:ACT94235.1, ECO:0000313|Proteomes:UP000002011}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700827 / DSM 18053 / CIP 107007 / KCTC 52180 / NS114
RC   {ECO:0000313|Proteomes:UP000002011};
RX   PubMed=21304649; DOI=10.4056/sigs.19262;
RA   Lang E., Lapidus A., Chertkov O., Brettin T., Detter J.C., Han C.,
RA   Copeland A., Glavina Del Rio T., Nolan M., Chen F., Lucas S., Tice H.,
RA   Cheng J.F., Land M., Hauser L., Chang Y.J., Jeffries C.D., Kopitz M.,
RA   Bruce D., Goodwin L., Pitluck S., Ovchinnikova G., Pati A., Ivanova N.,
RA   Mavrommatis K., Chen A., Palaniappan K., Chain P., Bristow J., Eisen J.A.,
RA   Markowitz V., Hugenholtz P., Goker M., Rohde M., Kyrpides N.C., Klenk H.P.;
RT   "Complete genome sequence of Dyadobacter fermentans type strain (NS114).";
RL   Stand. Genomic Sci. 1:133-140(2009).
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DR   EMBL; CP001619; ACT94235.1; -; Genomic_DNA.
DR   RefSeq; WP_015812484.1; NC_013037.1.
DR   AlphaFoldDB; C6W5L7; -.
DR   STRING; 471854.Dfer_3020; -.
DR   CAZy; GH33; Glycoside Hydrolase Family 33.
DR   KEGG; dfe:Dfer_3020; -.
DR   eggNOG; COG4409; Bacteria.
DR   HOGENOM; CLU_024620_1_0_10; -.
DR   OrthoDB; 7294637at2; -.
DR   Proteomes; UP000002011; Chromosome.
DR   GO; GO:0052794; F:exo-alpha-(2->3)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052795; F:exo-alpha-(2->6)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052796; F:exo-alpha-(2->8)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR   CDD; cd15482; Sialidase_non-viral; 1.
DR   Gene3D; 2.120.10.10; -; 1.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR036278; Sialidase_sf.
DR   PANTHER; PTHR10628; SIALIDASE; 1.
DR   PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR   Pfam; PF13088; BNR_2; 1.
DR   SUPFAM; SSF50939; Sialidases; 1.
PE   4: Predicted;
KW   Glycosidase {ECO:0000313|EMBL:ACT94235.1};
KW   Hydrolase {ECO:0000313|EMBL:ACT94235.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002011};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          47..363
FT                   /note="Sialidase"
FT                   /evidence="ECO:0000259|Pfam:PF13088"
SQ   SEQUENCE   388 AA;  42772 MW;  90812E1049FE600D CRC64;
     MRYLKYTLLL KLFVIMHYAI GQTPVFVSGS DGYKSYRIPA IVRTPAGDLL AFAEGRVGGS
     GDFGDIDIVM KRSRDGGKTW SAMQVVANYN DLQAGNPAPV MDLTDPAFPK GRLFLFFNTG
     NNHEGEVRKG KGLREVWYKT STDNGATWSE PENITTQVHR PKQPTVNAAY DFAEDWRSYA
     NTPGHALQLT EGKLKGRIYI PANHSAGDPK PKFTDYQAHG FYTDDHGKTF KLSETISVEG
     GNEATAAELS GGRLLFNARN QKGDVRARIV AISSDGGAKW DTTFFDQNLP DPVCEGSILT
     IGKSKGNNIL AFCNAADTQA RDNLTLRISF DDGKTWAKSY PVDKSTAGEK DFTAYSDIVK
     TGKQAIGVLY ERDGYKSIVF KEIRWDAK
//