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Protein

Xylose isomerase

Gene

xylA

Organism
Dyadobacter fermentans (strain ATCC 700827 / DSM 18053 / NS114)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei107UniRule annotation1
Active sitei110UniRule annotation1
Metal bindingi238Magnesium 1UniRule annotation1
Metal bindingi274Magnesium 1UniRule annotation1
Metal bindingi274Magnesium 2UniRule annotation1
Metal bindingi277Magnesium 2UniRule annotation1
Metal bindingi302Magnesium 1UniRule annotation1
Metal bindingi313Magnesium 2UniRule annotation1
Metal bindingi315Magnesium 2UniRule annotation1
Metal bindingi345Magnesium 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationImported

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotationSAAS annotation, Xylose metabolismUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotationSAAS annotation (EC:5.3.1.5UniRule annotationSAAS annotation)
Gene namesi
Name:xylAUniRule annotation
Ordered Locus Names:Dfer_4723Imported
OrganismiDyadobacter fermentans (strain ATCC 700827 / DSM 18053 / NS114)Imported
Taxonomic identifieri471854 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesCytophagiaCytophagalesCytophagaceaeDyadobacter
Proteomesi
  • UP000002011 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi471854.Dfer_4723.

Structurei

3D structure databases

ProteinModelPortaliC6W4V0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105C93. Bacteria.
COG2115. LUCA.
HOGENOMiHOG000252293.
KOiK01805.
OMAiHTFQHEL.
OrthoDBiPOG091H07LC.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A. 1 hit.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C6W4V0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSILLGEQEY FKGIGKISFE GPETDNPLAY RWYDENRVIA GKTMKDHLRF
60 70 80 90 100
AVAYWHTFCG AGLDPFGGPT LFYPWDKKAD AVDRAKDKAD AAFEFITKLG
110 120 130 140 150
LPYYCFHDVD VVDYDDDVRT NEKRLQALTA YLGEKQKASG VKLLWGTANL
160 170 180 190 200
FGHHRYMNGA STNPDFDVVA HAGAQIKMAL DATIALGGEN YVFWGGREGY
210 220 230 240 250
MSLLNTDMKR EQEHFAQMLK ISVAYARANG FKGKFFIEPK PCEPTKHQYD
260 270 280 290 300
YDAATVIGFL RQHDLLADFS LNLEVNHATL AGHTFEHELQ VAADAGILGS
310 320 330 340 350
IDANRGDYQN GWDTDQFPND IAEWTRALLV ILNAGGLQGG GINFDAKRRR
360 370 380 390 400
NSTDVDDVFH AHIGGIDTVA RALVIADKII QNGAYDEIRK NRYASFDGGK
410 420 430 440
GADFEKGALK LEDLFELAAT KGEPATTSGK QEYLENLINR FL
Length:442
Mass (Da):49,255
Last modified:September 22, 2009 - v1
Checksum:iC52FBDAE999C4DEA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001619 Genomic DNA. Translation: ACT95924.1.
RefSeqiWP_015814165.1. NC_013037.1.

Genome annotation databases

EnsemblBacteriaiACT95924; ACT95924; Dfer_4723.
KEGGidfe:Dfer_4723.
PATRICi21831065. VBIDyaFer416_4851.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001619 Genomic DNA. Translation: ACT95924.1.
RefSeqiWP_015814165.1. NC_013037.1.

3D structure databases

ProteinModelPortaliC6W4V0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi471854.Dfer_4723.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACT95924; ACT95924; Dfer_4723.
KEGGidfe:Dfer_4723.
PATRICi21831065. VBIDyaFer416_4851.

Phylogenomic databases

eggNOGiENOG4105C93. Bacteria.
COG2115. LUCA.
HOGENOMiHOG000252293.
KOiK01805.
OMAiHTFQHEL.
OrthoDBiPOG091H07LC.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A. 1 hit.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiC6W4V0_DYAFD
AccessioniPrimary (citable) accession number: C6W4V0
Entry historyi
Integrated into UniProtKB/TrEMBL: September 22, 2009
Last sequence update: September 22, 2009
Last modified: November 30, 2016
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.