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C6W244 (C6W244_DYAFD) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP MF_00323
EC=4.99.1.1 HAMAP MF_00323
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323
Ordered Locus Names:Dfer_4417
OrganismDyadobacter fermentans (strain ATCC 700827 / DSM 18053 / NS114) [Complete proteome] [HAMAP]
Taxonomic identifier471854 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Cytophagia › Cytophagales › Cytophagaceae › Dyadobacter

Protein attributes

Sequence length357 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323 SAAS SAAS001015

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323 SAAS SAAS001015

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323 RuleBase RU004185

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2091Iron By similarity HAMAP MF_00323
Metal binding3111Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
C6W244 [UniParc].

Last modified September 22, 2009. Version 1.
Checksum: E1A8D544ACF3BEC4

FASTA35740,792
        10         20         30         40         50         60 
MSATTLAQPF DTTTLNDVRK TGVLLVNLGT PDSPSVPDVR KYLRQFLMDE RVIDIPYVNR 

        70         80         90        100        110        120 
WFLINLVIAP FRAPKSAKVY KQLWRPDGSP LKTYGYSVKD KLQKVLGGDY VVELAMRYQN 

       130        140        150        160        170        180 
PSIEKALVAL RKECLTEIIV VPFFPQYASA STGSVYKEVM RVVKDWEVLP EIRFVNRFLE 

       190        200        210        220        230        240 
HPKFIKGFVD LGKKYMAQHD YDHFVFSYHG LPERQITKGD VTGSFCQFGS CCDKLDHRNQ 

       250        260        270        280        290        300 
HCYRAQCFET TRLLVKGLGI PEGKYTTCFQ SRLGKSPWIK PYTDEVIPEL TKKGVKSALA 

       310        320        330        340        350 
FSPAFVADCL ETTIEVGEEY KELFEKEGGV HWQLVESLND SDIWVECLED IVKNPAS

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001619 Genomic DNA. Translation: ACT95619.1.
RefSeqYP_003088784.1. NC_013037.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGC6W244.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID8228020.
GenomeReviewsGene locus Dfer_4417 in contig CP001619_GR.
KEGGdfe:Dfer_4417.
PATRIC21830441. VBIDyaFer416_4542.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMATIEEIGM.
ProtClustDBPRK00035.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC6W244_DYAFD
AccessionPrimary (citable) accession number: C6W244
Entry history
Integrated into UniProtKB/TrEMBL: September 22, 2009
Last sequence update: September 22, 2009
Last modified: December 14, 2011
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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