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C6W223

- C6W223_DYAFD

UniProt

C6W223 - C6W223_DYAFD

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Protein
Thymidine kinase
Gene
tdk, Dfer_4396
Organism
Dyadobacter fermentans (strain ATCC 700827 / DSM 18053 / NS114)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei97 – 971Proton acceptor By similarityUniRule annotation
Metal bindingi153 – 1531Zinc By similarityUniRule annotation
Metal bindingi156 – 1561Zinc By similarityUniRule annotation
Metal bindingi185 – 1851Zinc By similarityUniRule annotation
Metal bindingi188 – 1881Zinc By similarityUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi24 – 318ATP By similarityUniRule annotation
Nucleotide bindingi96 – 994ATP By similarityUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. thymidine kinase activity Source: UniProtKB-HAMAP
  3. zinc ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotationsImported, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotationSAAS annotations

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotations, Metal-bindingUniRule annotationSAAS annotations, Nucleotide-binding, ZincUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciDFER471854:GI24-4435-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotation
Ordered Locus Names:Dfer_4396Imported
OrganismiDyadobacter fermentans (strain ATCC 700827 / DSM 18053 / NS114)Imported
Taxonomic identifieri471854 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesCytophagiaCytophagalesCytophagaceaeDyadobacter
ProteomesiUP000002011: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotationSAAS annotations

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotations

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotationSAAS annotations

Protein-protein interaction databases

STRINGi471854.Dfer_4396.

Structurei

3D structure databases

ProteinModelPortaliC6W223.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1435.
HOGENOMiHOG000076390.
KOiK00857.
OMAiQAICLSC.
OrthoDBiEOG69D3J2.

Family and domain databases

HAMAPiMF_00124. Thymidine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

C6W223-1 [UniParc]FASTAAdd to Basket

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MFVEPSHRRE FQNPRTGWIE VICGSMFSGK TEELIRLLNR ARIARQRIQI    50
FKPALDKRYH EENIVSHNDN SIPSIPVQSS QQISDLAQDC EVVGIDEAQF 100
FDEGILAVCD QLANSGKRVI VAGLDMDYMG KPFGCMPQLM AIAEYVTKVH 150
AVCMVCGEVA SHSYRLSPSN ERVLLGETDH YEARCRRCFN LGEKATELFS 200
R 201
Length:201
Mass (Da):22,771
Last modified:September 22, 2009 - v1
Checksum:iCB8394C86ED6918F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001619 Genomic DNA. Translation: ACT95598.1.
RefSeqiYP_003088763.1. NC_013037.1.

Genome annotation databases

EnsemblBacteriaiACT95598; ACT95598; Dfer_4396.
GeneIDi8227999.
KEGGidfe:Dfer_4396.
PATRICi21830397. VBIDyaFer416_4520.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001619 Genomic DNA. Translation: ACT95598.1 .
RefSeqi YP_003088763.1. NC_013037.1.

3D structure databases

ProteinModelPortali C6W223.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 471854.Dfer_4396.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACT95598 ; ACT95598 ; Dfer_4396 .
GeneIDi 8227999.
KEGGi dfe:Dfer_4396.
PATRICi 21830397. VBIDyaFer416_4520.

Phylogenomic databases

eggNOGi COG1435.
HOGENOMi HOG000076390.
KOi K00857.
OMAi QAICLSC.
OrthoDBi EOG69D3J2.

Enzyme and pathway databases

BioCyci DFER471854:GI24-4435-MONOMER.

Family and domain databases

HAMAPi MF_00124. Thymidine_kinase.
InterProi IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view ]
PANTHERi PTHR11441. PTHR11441. 1 hit.
Pfami PF00265. TK. 1 hit.
[Graphical view ]
PIRSFi PIRSF035805. TK_cell. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
PROSITEi PS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700827 / DSM 18053 / NS114.

Entry informationi

Entry nameiC6W223_DYAFD
AccessioniPrimary (citable) accession number: C6W223
Entry historyi
Integrated into UniProtKB/TrEMBL: September 22, 2009
Last sequence update: September 22, 2009
Last modified: June 11, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi