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C6W109 (C6W109_DYAFD) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glutamate--tRNA ligase HAMAP MF_00022
EC=6.1.1.17 HAMAP MF_00022
Alternative name(s):
Glutamyl-tRNA synthetase HAMAP MF_00022
Gene names
Name:gltX HAMAP MF_00022
Ordered Locus Names:Dfer_4262
OrganismDyadobacter fermentans (strain ATCC 700827 / DSM 18053 / NS114) [Complete proteome] [HAMAP]
Taxonomic identifier471854 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Cytophagia › Cytophagales › Cytophagaceae › Dyadobacter

Protein attributes

Sequence length516 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) By similarity. HAMAP MF_00022

Catalytic activity

ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu). HAMAP MF_00022

Subunit structure

Monomer By similarity. HAMAP MF_00022

Subcellular location

Cytoplasm By similarity HAMAP MF_00022.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family. HAMAP MF_00022 RuleBase RU003489

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Motif12 – 2211"HIGH" region By similarity HAMAP MF_00022
Motif264 – 2685"KMSKS" region By similarity HAMAP MF_00022

Sites

Binding site2671ATP By similarity HAMAP MF_00022

Sequences

Sequence LengthMass (Da)Tools
C6W109 [UniParc].

Last modified September 22, 2009. Version 1.
Checksum: 0471251A4077C5A2

FASTA51657,922
        10         20         30         40         50         60 
MNNRPVRVRF APSPTGPLHA GGVRTALYNY LFARQQGGQM LLRIEDTDQN RYVPGAEAYI 

        70         80         90        100        110        120 
LEALEWLGIG IDEGPQQGGP HAPYRQSERK EMYREYAERL VQEGKAYYAF DTPEQLDDMR 

       130        140        150        160        170        180 
KRLEAAKVAA VQYNAITRTE MTNSLTLSAE ETQARLDSGD PYVIRMKISP KEDIRFNDLI 

       190        200        210        220        230        240 
RGWVVVHSSQ IDDKVLLKSD GMPTYHLANI VDDHLMGITH VIRGEEWLPS APLHVLLYRY 

       250        260        270        280        290        300 
LGWESTMPQF AHLPLLLKPD GNGKLSKRDA DLGGFPIFPL EWTDPNTGDK ARGFREEGYL 

       310        320        330        340        350        360 
PGATANFLAL LGWNAGTEQE IFSMDELIAS FSFDRVHKAG ARFDIQKANW FNQQYLKQLD 

       370        380        390        400        410        420 
DTAITGQLKP LYADKGIEVN DDQLAQIVHL LKDRVHFVKE IVSESLFLFS APEEYDQDVV 

       430        440        450        460        470        480 
IKKWNEEAVN AIGAFKDALA GFEGNFVAHD IKEVLSATME AAGIKMGKIM QALRLAVTGA 

       490        500        510 
GAGPDLMIIM EILGKDEVVK RLETALNRLS AQIRLA

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001619 Genomic DNA. Translation: ACT95464.1.
RefSeqYP_003088629.1. NC_013037.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGC6W109.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID8227865.
GenomeReviewsGene locus Dfer_4262 in contig CP001619_GR.
KEGGdfe:Dfer_4262.
PATRIC21830127. VBIDyaFer416_4385.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAESIIQFV.
ProtClustDBPRK01406.

Family and domain databases

HAMAPMF_00022_B. Glu_tRNA_synth_B.
[Tree]
InterProIPR008925. aa-tRNA-synth_I_codon-bd.
IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
IPR001412. aa-tRNA-synth_I_CS.
IPR004527. Glu-tRNA-synth_Ib_bac/mito.
IPR000924. Glu/Gln-tRNA-synth_Ib.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
Gene3DG3DSA:1.10.1160.10. Glu/Gln-tRNA-synth_Ic_a-bdl. 1 hit.
G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 2 hits.
G3DSA:1.10.10.350. tRNA_synt_bd. 1 hit.
KOK01885.
PANTHERPTHR10119. Glu_tRNA-synt_1c. 1 hit.
PTHR10119:SF1. PTHR10119:SF1. 1 hit.
PfamPF00749. tRNA-synt_1c. 1 hit.
[Graphical view]
PRINTSPR00987. TRNASYNTHGLU.
SUPFAMSSF48163. tRNA-synt_bind. 1 hit.
TIGRFAMsTIGR00464. GltX_bact. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC6W109_DYAFD
AccessionPrimary (citable) accession number: C6W109
Entry history
Integrated into UniProtKB/TrEMBL: September 22, 2009
Last sequence update: September 22, 2009
Last modified: January 25, 2012
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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