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C6VZY7 (C6VZY7_DYAFD) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase HAMAP MF_00061
Short name=CMK HAMAP MF_00061
EC=2.7.1.148 HAMAP MF_00061
Alternative name(s):
4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase HAMAP MF_00061
Gene names
Name:ispE HAMAP MF_00061
Ordered Locus Names:Dfer_4111
OrganismDyadobacter fermentans (strain ATCC 700827 / DSM 18053 / NS114) [Complete proteome] [HAMAP]
Taxonomic identifier471854 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Cytophagia › Cytophagales › Cytophagaceae › Dyadobacter

Protein attributes

Sequence length269 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol By similarity. HAMAP MF_00061

Catalytic activity

ATP + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol = ADP + 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol. HAMAP MF_00061

Pathway

Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 3/6. HAMAP MF_00061

Sequence similarities

Belongs to the GHMP kinase family. IspE subfamily. HAMAP MF_00061

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding90 – 10011ATP By similarity HAMAP MF_00061

Sites

Active site81 By similarity HAMAP MF_00061
Active site1321 By similarity HAMAP MF_00061

Sequences

Sequence LengthMass (Da)Tools
C6VZY7 [UniParc].

Last modified September 22, 2009. Version 1.
Checksum: AEB8760709441FD4

FASTA26929,773
        10         20         30         40         50         60 
MLVFPNAKIN IGLNIVEKRP DGFHNIESCF YPVGWSDALE ITQAEQFSFH ADGIAIPGNA 

        70         80         90        100        110        120 
SDNLCIKAYE MLRSDYHLPP VKIHLLKTVP IGAGLGGGSA DAAFAIKALN QLFNLNISVG 

       130        140        150        160        170        180 
EQEEYARRIG SDCAFFIRNK PMYCFGKGDE FDAIDINISG KWIALVNPGI HISTVEAYSG 

       190        200        210        220        230        240 
VVAKRSTGDL RTILSGPITG WKDHVRNDFE ATLFQKYPLL ADTKDKLYDL GAEYAAMSGS 

       250        260 
GSTLFGIFKE EQNVKQHFPD FRLWQGFLR

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001619 Genomic DNA. Translation: ACT95314.1.
RefSeqYP_003088479.1. NC_013037.1.

3D structure databases

ProteinModelPortalC6VZY7.
ModBaseSearch...

Protein-protein interaction databases

STRINGC6VZY7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID8227709.
GenomeReviewsGene locus Dfer_4111 in contig CP001619_GR.
KEGGdfe:Dfer_4111.
PATRIC21829809. VBIDyaFer416_4230.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMACQLARMS.
ProtClustDBPRK14609.

Family and domain databases

HAMAPMF_00061. IspE.
[Tree]
InterProIPR006204. GHMP_kinase.
IPR013750. GHMP_kinase_C.
IPR004424. IspE.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
[Graphical view]
Gene3DG3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit.
KOK00919.
PANTHERPTHR20861:SF2. IspE. 1 hit.
PfamPF08544. GHMP_kinases_C. 1 hit.
PF00288. GHMP_kinases_N. 1 hit.
[Graphical view]
PIRSFPIRSF010376. IspE. 1 hit.
SUPFAMSSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
TIGRFAMsTIGR00154. IspE. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC6VZY7_DYAFD
AccessionPrimary (citable) accession number: C6VZY7
Entry history
Integrated into UniProtKB/TrEMBL: September 22, 2009
Last sequence update: September 22, 2009
Last modified: December 14, 2011
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info