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C6VWI1 (C6VWI1_DYAFD) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
1-deoxy-D-xylulose-5-phosphate synthase HAMAP MF_00315
EC=2.2.1.7 HAMAP MF_00315
Alternative name(s):
1-deoxyxylulose-5-phosphate synthase HAMAP MF_00315
Gene names
Name:dxs HAMAP MF_00315
Ordered Locus Names:Dfer_3808
OrganismDyadobacter fermentans (strain ATCC 700827 / DSM 18053 / NS114) [Complete proteome] [HAMAP]
Taxonomic identifier471854 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Cytophagia › Cytophagales › Cytophagaceae › Dyadobacter

Protein attributes

Sequence length647 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) By similarity. HAMAP MF_00315 SAAS SAAS005477

Catalytic activity

Pyruvate + D-glyceraldehyde 3-phosphate = 1-deoxy-D-xylulose 5-phosphate + CO2. HAMAP MF_00315 SAAS SAAS005477

Cofactor

Binds 1 thiamine pyrophosphate per subunit By similarity. HAMAP MF_00315 SAAS SAAS005477

Pathway

Metabolic intermediate biosynthesis; 1-deoxy-D-xylulose 5-phosphate biosynthesis; 1-deoxy-D-xylulose 5-phosphate from D-glyceraldehyde 3-phosphate and pyruvate: step 1/1. HAMAP MF_00315 SAAS SAAS005477

Subunit structure

Homodimer By similarity. HAMAP MF_00315 SAAS SAAS005477

Sequence similarities

Belongs to the transketolase family. DXPS subfamily. HAMAP MF_00315

Sequences

Sequence LengthMass (Da)Tools
C6VWI1 [UniParc].

Last modified September 22, 2009. Version 1.
Checksum: 9F1D79A35E0CFE95

FASTA64770,850
        10         20         30         40         50         60 
MLITPGKLLA TINSPEDLRK LDSSQLPQVC NELRQFIIDN VSVYGGHFGA SLGVVELSVA 

        70         80         90        100        110        120 
LHYVFNTPDD QLVWDVGHQA YGHKILTGRR DDFHSNRVYG GLSGFPKRKE SIYDAFGVGH 

       130        140        150        160        170        180 
SSTSISSALG MAVASALEKN FQRQHIAIIG DGAMTAGLAF EGMNHAGATD SNLLIILNDN 

       190        200        210        220        230        240 
CMAIDPNVGA LKEYLTDITT SQTYNKFKDE VWNLLGKMSN FGKSAQEIVS KVETAMKTAI 

       250        260        270        280        290        300 
LRQSNLFESL GLRYFGPIDG NDISHLTEVL KDLKNIPGPK LLHCLTVKGK GYGPAEKDQT 

       310        320        330        340        350        360 
KWHAPGVFDK ITGEIKKKVY DTPQAPKYQD VFGHTIVELA KANPKIVGIT PAMPSGSSLN 

       370        380        390        400        410        420 
IMMEAVPERA FDVGIAEQHA VTFSAGMATR GEVVYCNIYS TFMQRAYDQV VHDVCIQELP 

       430        440        450        460        470        480 
VIFCLDRAGL VGADGPTHHG LYDIAYMRCI PNMVVASPMN EQELRNMMYT AQLESFQSGK 

       490        500        510        520        530        540 
NAFTIRYPRG NGVMPDWKTP FEEIQIGKGR KVRSGSDLAI LSLGPLGNFA LQACEDLEKQ 

       550        560        570        580        590        600 
GISASLYDMR FAKPLDEALL HEIFSSYERV ITLEDGCVQG GFGSAVVEFM ADNGYSSAIK 

       610        620        630        640 
RLGIADTIIE HGEPAELYHE CGIDTKGIVS ASVEVMQRRS RVASLMH

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001619 Genomic DNA. Translation: ACT95012.1.
RefSeqYP_003088177.1. NC_013037.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGC6VWI1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID8227402.
GenomeReviewsGene locus Dfer_3808 in contig CP001619_GR.
KEGGdfe:Dfer_3808.
PATRIC21829189. VBIDyaFer416_3924.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAEAMNAHA.
ProtClustDBPRK05444.

Family and domain databases

HAMAPMF_00315. DXP_synth.
[Tree]
InterProIPR005477. Dxylulose-5-P_synthase.
IPR009014. Transketo_C/Pyr-ferredox_oxred.
IPR015941. Transketolase-like_C.
IPR005475. Transketolase-like_Pyr-bd.
IPR020826. Transketolase_BS.
IPR005476. Transketolase_C.
IPR005474. Transketolase_N.
[Graphical view]
Gene3DG3DSA:3.40.50.920. Transketo_C_like. 1 hit.
KOK01662.
PfamPF02779. Transket_pyr. 1 hit.
PF02780. Transketolase_C. 1 hit.
[Graphical view]
SMARTSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMSSF52922. Transketo_C_like. 1 hit.
TIGRFAMsTIGR00204. Dxs. 1 hit.
PROSITEPS00801. TRANSKETOLASE_1. 1 hit.
PS00802. TRANSKETOLASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC6VWI1_DYAFD
AccessionPrimary (citable) accession number: C6VWI1
Entry history
Integrated into UniProtKB/TrEMBL: September 22, 2009
Last sequence update: September 22, 2009
Last modified: December 14, 2011
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info