Skip Header

Contribute Send feedback
Read comments (?) or add your own

C6VP68 (C6VP68_LACPJ) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 18. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Ferrochelatase HAMAP MF_00323 RuleBase RU000607
EC=4.99.1.1 HAMAP MF_00323 RuleBase RU000607
Alternative name(s):
Heme synthase HAMAP MF_00323
Protoheme ferro-lyase HAMAP MF_00323
Gene names
Name:hemH HAMAP MF_00323 EMBL ACT61983.1
Ordered Locus Names:JDM1_1096
OrganismLactobacillus plantarum (strain JDM1) [Complete proteome] [HAMAP]
Taxonomic identifier644042 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Lactobacillales › Lactobacillaceae › Lactobacillus

Protein attributes

Sequence length324 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the ferrous insertion into protoporphyrin IX By similarity. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Catalytic activity

Protoheme + 2 H+ = protoporphyrin + Fe2+. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Pathway

Porphyrin metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1. HAMAP MF_00323 RuleBase RU000607 SAAS SAAS001015

Subcellular location

Cytoplasm By similarity HAMAP MF_00323.

Sequence similarities

Belongs to the ferrochelatase family. HAMAP MF_00323 RuleBase RU004185

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding1841Iron By similarity HAMAP MF_00323
Metal binding2661Iron By similarity HAMAP MF_00323

Sequences

Sequence LengthMass (Da)Tools
C6VP68 [UniParc].

Last modified September 22, 2009. Version 1.
Checksum: 14F7B494C5F1822B

FASTA32436,371
        10         20         30         40         50         60 
MHPGLLLVNL GSPASPRTKD VKTYLQEFLS DPSVIEMPAA LWQPLLRGII LPTRSWRSAT 

        70         80         90        100        110        120 
FYQDSWLPQG SPLIVYSQAI CQQVQAALPD WDVRLAMTYG QPDIGATLKA MVADGCEKPI 

       130        140        150        160        170        180 
ILPLFPQYTQ STHGGIHRQV EATGLPHTFI DSFYDQPTYI HLLATKVWQS YQAHHYDAVI 

       190        200        210        220        230        240 
FSYHSIPTAM VRHGDPYQRE CEATTKAVLA ERPELPADKV ITAYQSKFGP MPWLKPYLKN 

       250        260        270        280        290        300 
ELMQLVELGK RNVLVVTPSF VVDCLETLEE DYVQNYQTFR ASGGDRFDLV PPMNKDTGFS 

       310        320 
QFLADLAIQK QEASNHAIAS SSKS

« Hide

References

[1]"Complete genome sequence of Lactobacillus plantarum JDM1."
Zhang Z.-Y., Liu C., Zhu Y.-Z., Zhong Y., Zhu Y.-Q., Zheng H.-J., Zhao G.-P., Wang S.-Y., Guo X.-K.
J. Bacteriol. 191:5020-5021(2009) [PubMed: 19465650] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001617 Genomic DNA. Translation: ACT61983.1.
RefSeqYP_003062680.1. NC_012984.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGC6VP68.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID8187805.
GenomeReviewsGene locus JDM1_1096 in contig CP001617_GR.
KEGGlpj:JDM1_1096.
PATRIC22242771. VBILacPla68346_1093.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMATIEEIGM.
ProtClustDBCLSK821272.

Family and domain databases

HAMAPMF_00323. Ferrochelatase.
[Tree]
InterProIPR001015. Ferrochelatase.
IPR019772. Ferrochelatase_AS.
[Graphical view]
KOK01772.
PANTHERPTHR11108. Ferrochelatase. 1 hit.
PfamPF00762. Ferrochelatase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00109. HemH. 1 hit.
PROSITEPS00534. FERROCHELATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC6VP68_LACPJ
AccessionPrimary (citable) accession number: C6VP68
Entry history
Integrated into UniProtKB/TrEMBL: September 22, 2009
Last sequence update: September 22, 2009
Last modified: December 14, 2011
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info