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C6V456

- C6V456_NEORI

UniProt

C6V456 - C6V456_NEORI

Protein
Submitted name:

Bifunctional purine biosynthesis protein PurH

Gene

purH

Organism
Neorickettsia risticii (strain Illinois)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 35 (01 Oct 2014)
      Sequence version 1 (22 Sep 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    10-formyltetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide = tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.SAAS annotation
    IMP + H2O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.SAAS annotation

    Pathwayi

    GO - Molecular functioni

    1. IMP cyclohydrolase activity Source: UniProtKB-EC
    2. phosphoribosylaminoimidazolecarboxamide formyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    HydrolaseSAAS annotationImported, TransferaseSAAS annotationImported

    Keywords - Biological processi

    Purine biosynthesisSAAS annotation

    Enzyme and pathway databases

    BioCyciNRIS434131:GJCC-182-MONOMER.
    UniPathwayiUPA00074; UER00133.
    UPA00074; UER00135.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Bifunctional purine biosynthesis protein PurHImported (EC:2.1.2.3Imported, EC:3.5.4.10Imported)
    Gene namesi
    Name:purHImported
    Ordered Locus Names:NRI_0180Imported
    OrganismiNeorickettsia risticii (strain Illinois)Imported
    Taxonomic identifieri434131 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesAnaplasmataceaeNeorickettsia
    ProteomesiUP000001627: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi434131.NRI_0180.

    Structurei

    3D structure databases

    ProteinModelPortaliC6V456.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiCOG0138.
    HOGENOMiHOG000230373.
    KOiK00602.
    OMAiRAFKTDP.
    OrthoDBiEOG6QCDFF.

    Family and domain databases

    Gene3Di3.40.140.20. 2 hits.
    3.40.50.1380. 1 hit.
    InterProiIPR024051. AICAR_Tfase_dom.
    IPR002695. AICARFT_IMPCHas.
    IPR016193. Cytidine_deaminase-like.
    IPR011607. MGS-like_dom.
    [Graphical view]
    PANTHERiPTHR11692. PTHR11692. 1 hit.
    PfamiPF01808. AICARFT_IMPCHas. 1 hit.
    PF02142. MGS. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000414. AICARFT_IMPCHas. 1 hit.
    SMARTiSM00798. AICARFT_IMPCHas. 1 hit.
    SM00851. MGS. 1 hit.
    [Graphical view]
    SUPFAMiSSF52335. SSF52335. 1 hit.
    SSF53927. SSF53927. 1 hit.
    TIGRFAMsiTIGR00355. purH. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    C6V456-1 [UniParc]FASTAAdd to Basket

    « Hide

    MIKRALISVY DKTDLLPLAY KLQAANVEII ATGKTHQYLL ENQIRATNLS    50
    DYTHQPEILG GRVKTLHPVI HAGLLADPAL HEAEMQTLAI KQIDLVVVNL 100
    YPFEKCVNSG APESEIIENI DIGGVSLLRS AAKNFKNVCV LSDPSDYSTF 150
    DVNPTLSFRS KMARKAFARV ARYDCKIAEW FASSTSLPEV LNLSVMKKND 200
    FRYGENPHQN ASFYSDGEFP LTKLQGKELS YNNLLDLDSA LSIVTNFTEP 250
    TCAIIKHTNP CGVASHKSSL EQAYEKALAA DSLSAFGGVV ALNQIVTRNV 300
    AEKLLNTFFE VIVAYGITQD AILLFSNKPN LRVLTYKSYT APEKNMLSLL 350
    GGLLVQSGNT KLFQDFEIVT KRQPTNEELN QLVFAWKICK YVKSNAIVTA 400
    HDYTTVGIGA GQMSRVKSVE IALGKSKVGQ PLAMASDAFF PFADSIELAA 450
    KNGVESIIQP GGSIRDKEVI EAANHHNIAM IFTRMRHFRH 490
    Length:490
    Mass (Da):54,078
    Last modified:September 22, 2009 - v1
    Checksum:i9B3760CF54C6FDC5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001431 Genomic DNA. Translation: ACT69171.1.
    RefSeqiWP_015816062.1. NC_013009.1.
    YP_003081410.1. NC_013009.1.

    Genome annotation databases

    EnsemblBacteriaiACT69171; ACT69171; NRI_0180.
    GeneIDi8220261.
    KEGGinri:NRI_0180.
    PATRICi22678652. VBINeoRis104330_0169.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001431 Genomic DNA. Translation: ACT69171.1 .
    RefSeqi WP_015816062.1. NC_013009.1.
    YP_003081410.1. NC_013009.1.

    3D structure databases

    ProteinModelPortali C6V456.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 434131.NRI_0180.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACT69171 ; ACT69171 ; NRI_0180 .
    GeneIDi 8220261.
    KEGGi nri:NRI_0180.
    PATRICi 22678652. VBINeoRis104330_0169.

    Phylogenomic databases

    eggNOGi COG0138.
    HOGENOMi HOG000230373.
    KOi K00602.
    OMAi RAFKTDP.
    OrthoDBi EOG6QCDFF.

    Enzyme and pathway databases

    UniPathwayi UPA00074 ; UER00133 .
    UPA00074 ; UER00135 .
    BioCyci NRIS434131:GJCC-182-MONOMER.

    Family and domain databases

    Gene3Di 3.40.140.20. 2 hits.
    3.40.50.1380. 1 hit.
    InterProi IPR024051. AICAR_Tfase_dom.
    IPR002695. AICARFT_IMPCHas.
    IPR016193. Cytidine_deaminase-like.
    IPR011607. MGS-like_dom.
    [Graphical view ]
    PANTHERi PTHR11692. PTHR11692. 1 hit.
    Pfami PF01808. AICARFT_IMPCHas. 1 hit.
    PF02142. MGS. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000414. AICARFT_IMPCHas. 1 hit.
    SMARTi SM00798. AICARFT_IMPCHas. 1 hit.
    SM00851. MGS. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52335. SSF52335. 1 hit.
    SSF53927. SSF53927. 1 hit.
    TIGRFAMsi TIGR00355. purH. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Analysis of complete genome sequence of Neorickettsia risticii: causative agent of Potomac horse fever."
      Lin M., Zhang C., Gibson K., Rikihisa Y.
      Nucleic Acids Res. 37:6076-6091(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: IllinoisImported.

    Entry informationi

    Entry nameiC6V456_NEORI
    AccessioniPrimary (citable) accession number: C6V456
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 22, 2009
    Last sequence update: September 22, 2009
    Last modified: October 1, 2014
    This is version 35 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported, Multifunctional enzymeSAAS annotation

    External Data

    Dasty 3