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C6V456

- C6V456_NEORI

UniProt

C6V456 - C6V456_NEORI

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Protein
Submitted name:

Bifunctional purine biosynthesis protein PurH

Gene
purH, NRI_0180
Organism
Neorickettsia risticii (strain Illinois)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

Catalytic activityi

10-formyltetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide = tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.SAAS annotations
IMP + H2O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.SAAS annotations

Pathwayi

GO - Molecular functioni

  1. IMP cyclohydrolase activity Source: UniProtKB-EC
  2. phosphoribosylaminoimidazolecarboxamide formyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseSAAS annotationsImported, TransferaseSAAS annotationsImported

Keywords - Biological processi

Purine biosynthesisSAAS annotations

Enzyme and pathway databases

BioCyciNRIS434131:GJCC-182-MONOMER.
UniPathwayiUPA00074; UER00133.
UPA00074; UER00135.

Names & Taxonomyi

Protein namesi
Submitted name:
Bifunctional purine biosynthesis protein PurHImported (EC:2.1.2.3Imported, EC:3.5.4.10Imported)
Gene namesi
Name:purHImported
Ordered Locus Names:NRI_0180Imported
OrganismiNeorickettsia risticii (strain Illinois)Imported
Taxonomic identifieri434131 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesAnaplasmataceaeNeorickettsia
ProteomesiUP000001627: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi434131.NRI_0180.

Structurei

3D structure databases

ProteinModelPortaliC6V456.

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0138.
HOGENOMiHOG000230373.
KOiK00602.
OMAiRAFKTDP.
OrthoDBiEOG6QCDFF.

Family and domain databases

Gene3Di3.40.140.20. 2 hits.
3.40.50.1380. 1 hit.
InterProiIPR024051. AICAR_Tfase_dom.
IPR002695. AICARFT_IMPCHas.
IPR016193. Cytidine_deaminase-like.
IPR011607. MGS-like_dom.
[Graphical view]
PANTHERiPTHR11692. PTHR11692. 1 hit.
PfamiPF01808. AICARFT_IMPCHas. 1 hit.
PF02142. MGS. 1 hit.
[Graphical view]
PIRSFiPIRSF000414. AICARFT_IMPCHas. 1 hit.
SMARTiSM00798. AICARFT_IMPCHas. 1 hit.
SM00851. MGS. 1 hit.
[Graphical view]
SUPFAMiSSF52335. SSF52335. 1 hit.
SSF53927. SSF53927. 1 hit.
TIGRFAMsiTIGR00355. purH. 1 hit.

Sequencei

Sequence statusi: Complete.

C6V456-1 [UniParc]FASTAAdd to Basket

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MIKRALISVY DKTDLLPLAY KLQAANVEII ATGKTHQYLL ENQIRATNLS    50
DYTHQPEILG GRVKTLHPVI HAGLLADPAL HEAEMQTLAI KQIDLVVVNL 100
YPFEKCVNSG APESEIIENI DIGGVSLLRS AAKNFKNVCV LSDPSDYSTF 150
DVNPTLSFRS KMARKAFARV ARYDCKIAEW FASSTSLPEV LNLSVMKKND 200
FRYGENPHQN ASFYSDGEFP LTKLQGKELS YNNLLDLDSA LSIVTNFTEP 250
TCAIIKHTNP CGVASHKSSL EQAYEKALAA DSLSAFGGVV ALNQIVTRNV 300
AEKLLNTFFE VIVAYGITQD AILLFSNKPN LRVLTYKSYT APEKNMLSLL 350
GGLLVQSGNT KLFQDFEIVT KRQPTNEELN QLVFAWKICK YVKSNAIVTA 400
HDYTTVGIGA GQMSRVKSVE IALGKSKVGQ PLAMASDAFF PFADSIELAA 450
KNGVESIIQP GGSIRDKEVI EAANHHNIAM IFTRMRHFRH 490
Length:490
Mass (Da):54,078
Last modified:September 22, 2009 - v1
Checksum:i9B3760CF54C6FDC5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001431 Genomic DNA. Translation: ACT69171.1.
RefSeqiWP_015816062.1. NC_013009.1.
YP_003081410.1. NC_013009.1.

Genome annotation databases

EnsemblBacteriaiACT69171; ACT69171; NRI_0180.
GeneIDi8220261.
KEGGinri:NRI_0180.
PATRICi22678652. VBINeoRis104330_0169.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001431 Genomic DNA. Translation: ACT69171.1 .
RefSeqi WP_015816062.1. NC_013009.1.
YP_003081410.1. NC_013009.1.

3D structure databases

ProteinModelPortali C6V456.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 434131.NRI_0180.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACT69171 ; ACT69171 ; NRI_0180 .
GeneIDi 8220261.
KEGGi nri:NRI_0180.
PATRICi 22678652. VBINeoRis104330_0169.

Phylogenomic databases

eggNOGi COG0138.
HOGENOMi HOG000230373.
KOi K00602.
OMAi RAFKTDP.
OrthoDBi EOG6QCDFF.

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00133 .
UPA00074 ; UER00135 .
BioCyci NRIS434131:GJCC-182-MONOMER.

Family and domain databases

Gene3Di 3.40.140.20. 2 hits.
3.40.50.1380. 1 hit.
InterProi IPR024051. AICAR_Tfase_dom.
IPR002695. AICARFT_IMPCHas.
IPR016193. Cytidine_deaminase-like.
IPR011607. MGS-like_dom.
[Graphical view ]
PANTHERi PTHR11692. PTHR11692. 1 hit.
Pfami PF01808. AICARFT_IMPCHas. 1 hit.
PF02142. MGS. 1 hit.
[Graphical view ]
PIRSFi PIRSF000414. AICARFT_IMPCHas. 1 hit.
SMARTi SM00798. AICARFT_IMPCHas. 1 hit.
SM00851. MGS. 1 hit.
[Graphical view ]
SUPFAMi SSF52335. SSF52335. 1 hit.
SSF53927. SSF53927. 1 hit.
TIGRFAMsi TIGR00355. purH. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Analysis of complete genome sequence of Neorickettsia risticii: causative agent of Potomac horse fever."
    Lin M., Zhang C., Gibson K., Rikihisa Y.
    Nucleic Acids Res. 37:6076-6091(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: IllinoisImported.

Entry informationi

Entry nameiC6V456_NEORI
AccessioniPrimary (citable) accession number: C6V456
Entry historyi
Integrated into UniProtKB/TrEMBL: September 22, 2009
Last sequence update: September 22, 2009
Last modified: September 3, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Multifunctional enzymeSAAS annotations

External Data

Dasty 3

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