C6V043 (C6V043_ECO5T) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Ureidoglycolate hydrolase HAMAP MF_00616
EC=3.5.3.19 HAMAP MF_00616

Gene names

Name:	allA HAMAP MF_00616 EMBL ACT70456.1
Ordered Locus Names:	ECSP_0580

Organism

Escherichia coli O157:H7 (strain TW14359 / EHEC) [Complete proteome] [HAMAP]

Taxonomic identifier

544404 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	160 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the anaerobic utilization of allantoin. Reinforces the induction of genes involved in the degradation of allantoin and glyoxylate by producing glyoxylate By similarity. HAMAP MF_00616
Catalytic activity	(S)-ureidoglycolate + H2O = glyoxylate + 2 NH3 + CO2. HAMAP MF_00616 SAAS SAAS023525
Pathway	Nitrogen metabolism; (S)-allantoin degradation; glyoxylate from (S)-ureidoglycolate: step 1/1. HAMAP MF_00616 SAAS SAAS023525
Subunit structure	Homodimer By similarity. HAMAP MF_00616 SAAS SAAS023525
Sequence similarities	Belongs to the ureidoglycolate hydrolase family. HAMAP MF_00616

Ontologies

Keywords
Biological process	Purine metabolism HAMAP MF_00616 SAAS SAAS023525
Molecular function	Hydrolase HAMAP MF_00616 SAAS SAAS023525 EMBL ACT70456.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	allantoin catabolic process Inferred from electronic annotation. Source: InterPro purine base catabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	ureidoglycolate hydrolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C6V043 [UniParc]. Last modified September 22, 2009. Version 1. Checksum: E39014610FE93FC6	FASTA	160	18,223
	10 20 30 40 50 60 MKLQVLPLSQ EAFSAYGDVI ETQQRDFFHI NNGLVERYHD LALVEILEQD RTLISINRAQ 70 80 90 100 110 120 PANLPLTIHE LERHPLGTQA FIPMKGEVFV VVVALGDDKP DLSTLRAFIT NGEQGVNYHR 130 140 150 160 NVWHHPLFAW QRVTDFLTID RGGSDNCDVE SIPEQELCFA

References

[1]

"Analysis of the genome of the Escherichia coli O157:H7 2006 spinach-associated outbreak isolate indicates candidate genes that may enhance virulence." Kulasekara B.R., Jacobs M., Zhou Y., Wu Z., Sims E., Saenphimmachak C., Rohmer L., Ritchie J.M., Radey M., McKevitt M., Freeman T.L., Hayden H., Haugen E., Gillett W., Fong C., Chang J., Beskhlebnaya V., Waldor M.K. , Samadpour M., Whittam T.S., Kaul R., Brittnacher M., Miller S.I. Infect. Immun. 77:3713-3721(2009) [PubMed: 19564389] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001368 Genomic DNA. Translation: ACT70456.1.
RefSeq	YP_003076532.1. NC_013008.1.
3D structure databases
ProteinModelPortal	C6V043.
SMR	C6V043. Positions 1-160.
ModBase	Search...
Protein-protein interaction databases
STRING	C6V043.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBESCT00000165354; EBESCP00000155708; EBESCG00000166408.
GeneID	8215146.
GenomeReviews	Gene locus ECSP_0580 in contig CP001368_GR.
KEGG	etw:ECSP_0580.
PATRIC	18385015. VBIEscCol9396_0587.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000010044.
OMA	SQAFIPM.
ProtClustDB	PRK03606.
Family and domain databases
HAMAP	MF_00616. Ureidogly_hydro. [Tree]
InterPro	IPR011051. Cupin_RmlC_type. IPR007247. Ureidogly_hydro. IPR023525. Ureidogly_hydro_bac. IPR024060. Ureidoglycolate_hydrolase_dom. [Graphical view]
Gene3D	G3DSA:2.60.120.480. G3DSA:2.60.120.480. 1 hit.
KO	K01483.
PANTHER	PTHR21221. Ureidogly_hydro. 1 hit.
Pfam	PF04115. Ureidogly_hydro. 1 hit. [Graphical view]
PIRSF	PIRSF017306. Ureidogly_hydro. 1 hit.
SUPFAM	SSF51182. RmlC_like_cupin. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C6V043_ECO5T

Accession

Primary (citable) accession number: C6V043

Entry history

Integrated into UniProtKB/TrEMBL:	September 22, 2009
Last sequence update:	September 22, 2009
Last modified:	December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)