C6UWQ9 (C6UWQ9_ECO5T) Unreviewed, UniProtKB/TrEMBL
Last modified
May 1, 2013.
Version 34.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize orderNames and origin
| Protein names | Recommended name: Glutamate-1-semialdehyde 2,1-aminomutase HAMAP-Rule MF_00375 Short name=GSA HAMAP-Rule MF_00375 EC=5.4.3.8 HAMAP-Rule MF_00375 Alternative name(s): Glutamate-1-semialdehyde aminotransferase HAMAP-Rule MF_00375 | ||||
| Gene names |
| ||||
| Organism | Escherichia coli O157:H7 (strain TW14359 / EHEC) [Complete proteome] [HAMAP] EMBL ACT70050.1 | ||||
| Taxonomic identifier | 544404 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › ![]() |
Protein attributes
| Sequence length | 426 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | (S)-4-amino-5-oxopentanoate = 5-aminolevulinate. HAMAP-Rule MF_00375 SAAS SAAS004639 |
| Cofactor | Pyridoxal phosphate By similarity. HAMAP-Rule MF_00375 SAAS SAAS004639 |
| Pathway | Porphyrin biosynthesis; chlorophyll biosynthesis. HAMAP-Rule MF_00375 Porphyrin metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from L-glutamyl-tRNA(Glu): step 2/2. HAMAP-Rule MF_00375 SAAS SAAS004639 |
| Subunit structure | Homodimer By similarity. HAMAP-Rule MF_00375 |
| Subcellular location | Cytoplasm By similarity HAMAP-Rule MF_00375 SAAS SAAS004639. |
| Sequence similarities | Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. HAMAP-Rule MF_00375 |
Ontologies
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Amino acid modifications | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Modified residue | 265 | 1 | N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_00375 | ||||||
Sequences
| ||||||||||||||||||
References
| [1] | "Analysis of the genome of the Escherichia coli O157:H7 2006 spinach-associated outbreak isolate indicates candidate genes that may enhance virulence." Kulasekara B.R., Jacobs M., Zhou Y., Wu Z., Sims E., Saenphimmachak C., Rohmer L., Ritchie J.M., Radey M., McKevitt M., Freeman T.L., Hayden H., Haugen E., Gillett W., Fong C., Chang J., Beskhlebnaya V., Waldor M.K. Miller S.I.Infect. Immun. 77:3713-3721(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TW14359 / EHEC. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP001368 Genomic DNA. Translation: ACT70050.1. |
| RefSeq | YP_003076126.1. NC_013008.1. |
3D structure databases | |
| ProteinModelPortal | C6UWQ9. |
| SMR | C6UWQ9. Positions 2-426. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | 544404.ECSP_0155. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | ACT70050; ACT70050; ECSP_0155. |
| GeneID | 8214721. |
| KEGG | etw:ECSP_0155. |
| PATRIC | 18384146. VBIEscCol9396_0162. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG0001. |
| HOGENOM | HOG000020210. |
| KO | K01845. |
| OMA | FNGNPIS. |
| ProtClustDB | PRK00062. |
Enzyme and pathway databases | |
| UniPathway | UPA00251; UER00317. UPA00668. |
Family and domain databases | |
| Gene3D | 3.40.640.10. 1 hit. 3.90.1150.10. 2 hits. |
| HAMAP | MF_00375. HemL_aminotrans_3. |
| InterPro | IPR004639. 4pyrrol_synth_GluAld_NH2Trfase. IPR005814. Aminotrans_3. IPR015424. PyrdxlP-dep_Trfase. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view] |
| PANTHER | PTHR11986. PTHR11986. 1 hit. PTHR11986:SF5. PTHR11986:SF5. 1 hit. |
| Pfam | PF00202. Aminotran_3. 1 hit. [Graphical view] |
| SUPFAM | SSF53383. PyrdxlP-dep_Trfase_major. 1 hit. |
| TIGRFAMs | TIGR00713. hemL. 1 hit. |
| PROSITE | PS00600. AA_TRANSFER_CLASS_3. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | C6UWQ9_ECO5T | ||||||||
| Accession | Primary (citable) accession number: C6UWQ9 | ||||||||
| Entry history |
| ||||||||
| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||

Clusters with
