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C6UV34 (C6UV34_ECO5T) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Predicted dethiobiotin synthetase EMBL ACT71971.1
Gene names
Name:ynfK EMBL ACT71971.1
Ordered Locus Names:ECSP_2157
OrganismEscherichia coli O157:H7 (strain TW14359 / EHEC) [Complete proteome] [HAMAP]
Taxonomic identifier544404 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length231 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring By similarity. SAAS SAAS004472

Catalytic activity

ATP + 7,8-diaminononanoate + CO2 = ADP + phosphate + dethiobiotin. SAAS SAAS004472

Cofactor

Magnesium By similarity. SAAS SAAS004472

Pathway

Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 1/2. SAAS SAAS004472

Subcellular location

Cytoplasm By similarity SAAS SAAS004472.

Sequences

Sequence LengthMass (Da)Tools
C6UV34 [UniParc].

Last modified September 22, 2009. Version 1.
Checksum: 35A04911309A99B0

FASTA23124,981
        10         20         30         40         50         60 
MLKRFFITGT DTSVGKTVVS RALLQALASQ GKTVAGYKPV AKGSKETPEG LRNKDALVLQ 

        70         80         90        100        110        120 
SVSTIELPYE AVNPIALSEE ESSVAHSCPI NYTLISNGLA NLTEKVDHVV VEGTGGWRSL 

       130        140        150        160        170        180 
MNDLRPLSEW VVQEQLPVLM VVGIQEGCIN HALLTAQAIA NDGLPLIGWV ANRINPGLAH 

       190        200        210        220        230 
YAEIIDVLGK KLPAPLIGEL PYLPRAEQRE LGQYIRLAML RSVLAVDRVT V

« Hide

References

[1]"Analysis of the genome of the Escherichia coli O157:H7 2006 spinach-associated outbreak isolate indicates candidate genes that may enhance virulence."
Kulasekara B.R., Jacobs M., Zhou Y., Wu Z., Sims E., Saenphimmachak C., Rohmer L., Ritchie J.M., Radey M., McKevitt M., Freeman T.L., Hayden H., Haugen E., Gillett W., Fong C., Chang J., Beskhlebnaya V., Waldor M.K. expand/collapse author list , Samadpour M., Whittam T.S., Kaul R., Brittnacher M., Miller S.I.
Infect. Immun. 77:3713-3721(2009) [PubMed: 19564389] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001368 Genomic DNA. Translation: ACT71971.1.
RefSeqYP_003078047.1. NC_013008.1.

3D structure databases

ProteinModelPortalC6UV34.
SMRC6UV34. Positions 2-220.
ModBaseSearch...

Protein-protein interaction databases

STRINGC6UV34.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBESCT00000170027; EBESCP00000157308; EBESCG00000165502.
GeneID8216723.
GenomeReviewsGene locus ECSP_2157 in contig CP001368_GR.
KEGGetw:ECSP_2157.
PATRIC18388318. VBIEscCol9396_2206.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000010427.
OMAINPGLSH.
ProtClustDBPRK12374.

Family and domain databases

HAMAPMF_00336. BioD.
[Tree]
InterProIPR002586. CbiA_P_synth.
IPR004472. DTB_synth_BioD.
[Graphical view]
KOK01935.
PfamPF01656. CbiA. 1 hit.
[Graphical view]
PIRSFPIRSF006755. DTB_synth. 1 hit.
TIGRFAMsTIGR00347. BioD. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC6UV34_ECO5T
AccessionPrimary (citable) accession number: C6UV34
Entry history
Integrated into UniProtKB/TrEMBL: September 22, 2009
Last sequence update: September 22, 2009
Last modified: December 14, 2011
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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