C6UU12 (C6UU12_ECO5T) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Tartronate semialdehyde reductase EMBL ACT73834.1

Gene names

Name:	garR EMBL ACT73834.1
Ordered Locus Names:	ECSP_4096 EMBL ACT73834.1

Organism

Escherichia coli O157:H7 (strain TW14359 / EHEC) [Complete proteome] [HAMAP] EMBL ACT73834.1

Taxonomic identifier

544404 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli › Escherichia coli O157:H7

Protein attributes

Sequence length	294 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glyoxylate metabolic process Inferred from electronic annotation. Source: InterPro pentose-phosphate shunt Inferred from electronic annotation. Source: InterPro valine metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	2-hydroxy-3-oxopropionate reductase activity Inferred from electronic annotation. Source: InterPro 3-hydroxyisobutyrate dehydrogenase activity Inferred from electronic annotation. Source: InterPro coenzyme binding Inferred from electronic annotation. Source: InterPro nucleotide binding Inferred from electronic annotation. Source: InterPro phosphogluconate dehydrogenase (decarboxylating) activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C6UU12 [UniParc]. Last modified September 22, 2009. Version 1. Checksum: 17DA392C2253278C	FASTA	294	30,427
	10 20 30 40 50 60 MKVGFIGLGI MGKPMSKNLL KAGYSLVVAD RNPEAIADVI AAGAETASTA KAIAEQCDVI 70 80 90 100 110 120 ITMLPNSPHV KEVALGENGI IEGAKPGTVL IDMSSIAPLA SREISEALKA KGIDMLDAPV 130 140 150 160 170 180 SGGEPKAIDG TLSVMVGGDK AIFDKYYDLM KAMAGSVVHT GEIGAGNVTK LANQVIVALN 190 200 210 220 230 240 IAAMSEALTL ATKAGVNPDL VYQAIRGGLA GSTVLDAKAP MVMDRNFKPG FRIDLHIKDL 250 260 270 280 290 ANALDTSHGV GAQLPLTAAV MEMMQALRAD GLGTADHSAL ACYYEKLAKV EVTR

References

[1]

"Analysis of the genome of the Escherichia coli O157:H7 2006 spinach-associated outbreak isolate indicates candidate genes that may enhance virulence." Kulasekara B.R., Jacobs M., Zhou Y., Wu Z., Sims E., Saenphimmachak C., Rohmer L., Ritchie J.M., Radey M., McKevitt M., Freeman T.L., Hayden H., Haugen E., Gillett W., Fong C., Chang J., Beskhlebnaya V., Waldor M.K. , Samadpour M., Whittam T.S., Kaul R., Brittnacher M., Miller S.I. Infect. Immun. 77:3713-3721(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TW14359 / EHEC.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001368 Genomic DNA. Translation: ACT73834.1.
RefSeq	YP_003079910.1. NC_013008.1.
3D structure databases
ProteinModelPortal	C6UU12.
SMR	C6UU12. Positions 1-294.
ModBase	Search...
Protein-protein interaction databases
STRING	544404.ECSP_4096.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACT73834; ACT73834; ECSP_4096.
GeneID	8218662.
KEGG	etw:ECSP_4096.
PATRIC	18392323. VBIEscCol9396_4161.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2084.
HOGENOM	HOG000219608.
KO	K00042.
OMA	GAINAPM.
ProtClustDB	PRK11559.
Family and domain databases
Gene3D	1.10.1040.10. 1 hit. 3.40.50.720. 1 hit.
InterPro	IPR002204. 3-OH-isobutyrate_DH-rel_CS. IPR008927. 6-PGluconate_DH_C-like. IPR006115. 6PGDH_NADP-bd. IPR013328. DH_multihelical. IPR015815. HIBADH-type. IPR016040. NAD(P)-bd_dom. IPR006398. Tartro_sem_red. [Graphical view]
PANTHER	PTHR22981. PTHR22981. 1 hit.
Pfam	PF03446. NAD_binding_2. 1 hit. [Graphical view]
PIRSF	PIRSF000103. HIBADH. 1 hit.
SUPFAM	SSF48179. 6DGDH_C_like. 1 hit.
TIGRFAMs	TIGR01505. tartro_sem_red. 1 hit.
PROSITE	PS00895. 3_HYDROXYISOBUT_DH. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C6UU12_ECO5T

Accession

Primary (citable) accession number: C6UU12

Entry history

Integrated into UniProtKB/TrEMBL:	September 22, 2009
Last sequence update:	September 22, 2009
Last modified:	May 1, 2013
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)