C6URV2 (C6URV2_ECO5T) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Lysozyme RuleBase RU003788
EC=3.2.1.17 RuleBase RU003788

Gene names

Ordered Locus Names:

ECSP_1529 EMBL ACT71370.1

Organism

Escherichia coli O157:H7 (strain TW14359 / EHEC) [Complete proteome] [HAMAP] EMBL ACT71370.1

Taxonomic identifier

544404 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli › Escherichia coli O157:H7

Protein attributes

Sequence length	158 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. RuleBase RU003788
Sequence similarities	Belongs to the glycosyl hydrolase 24 family. RuleBase RU003788

Ontologies

Keywords
Molecular function	Antimicrobial Bacteriolytic enzyme RuleBase RU003788 Glycosidase RuleBase RU003788 Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	cell wall macromolecule catabolic process Inferred from electronic annotation. Source: InterPro cytolysis Inferred from electronic annotation. Source: UniProtKB-KW defense response to bacterium Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan catabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	lysozyme activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C6URV2 [UniParc]. Last modified September 22, 2009. Version 1. Checksum: FC6C8C236D24CAFD	FASTA	158	17,816
	10 20 30 40 50 60 MQNLNPQRKA FLDMLAWSEG TDNGRQPTRN HGYDVIVGGE LFTDYSDHPR KLVTLHPKLK 70 80 90 100 110 120 STAAGRYQLL SRWWDAYRKQ LGLKDFSPKS QDAVALQQIK ERGALPMIDR GDIRQAIDRC 130 140 150 SNIWASLPGA GYGQFEHKAD SLIAKFKEAG GTVRESEV

References

[1]

"Analysis of the genome of the Escherichia coli O157:H7 2006 spinach-associated outbreak isolate indicates candidate genes that may enhance virulence." Kulasekara B.R., Jacobs M., Zhou Y., Wu Z., Sims E., Saenphimmachak C., Rohmer L., Ritchie J.M., Radey M., McKevitt M., Freeman T.L., Hayden H., Haugen E., Gillett W., Fong C., Chang J., Beskhlebnaya V., Waldor M.K. , Samadpour M., Whittam T.S., Kaul R., Brittnacher M., Miller S.I. Infect. Immun. 77:3713-3721(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: TW14359 / EHEC.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001368 Genomic DNA. Translation: ACT71370.1.
RefSeq	YP_003077446.1. NC_013008.1.
3D structure databases
ProteinModelPortal	C6URV2.
SMR	C6URV2. Positions 1-154.
ModBase	Search...
Protein-protein interaction databases
STRING	544404.ECSP_1529.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACT71370; ACT71370; ECSP_1529.
GeneID	8216095.
KEGG	etw:ECSP_1529.
PATRIC	18386968. VBIEscCol9396_1542.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG4678.
HOGENOM	HOG000118549.
OMA	HSAMARL.
ProtClustDB	CLSK879973.
Family and domain databases
InterPro	IPR002196. Glyco_hydro_24. IPR023346. Lysozyme-like_dom. [Graphical view]
Pfam	PF00959. Phage_lysozyme. 1 hit. [Graphical view]
SUPFAM	SSF53955. SSF53955. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C6URV2_ECO5T

Accession

Primary (citable) accession number: C6URV2

Entry history

Integrated into UniProtKB/TrEMBL:	September 22, 2009
Last sequence update:	September 22, 2009
Last modified:	May 1, 2013
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)