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C6UBE6 (C6UBE6_ECOBR) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 17. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-phenylpropionate/cinnamic acid dioxygenase subunit beta HAMAP MF_01649
EC=1.14.12.19 HAMAP MF_01649
Alternative name(s):
Digoxigenin subunit beta HAMAP MF_01649
Gene names
Name:hcaF HAMAP MF_01649
Ordered Locus Names:ECB_02431
OrganismEscherichia coli (strain B / REL606) [Complete proteome] [HAMAP] EMBL ACT40085.1
Taxonomic identifier413997 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length172 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of the multicomponent 3-phenylpropionate dioxygenase. Converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol), respectively By similarity. HAMAP MF_01649

Catalytic activity

3-phenylpropanoic acid + NADH + O2 = cis-3-(2-carboxyethyl)-3,5-cyclohexadiene-1,2-diol + NAD+. HAMAP MF_01649

Cinnamic acid + H+ + NADH + O2 = cis-3-(2-carboxyethenyl)-3,5-cyclohexadiene-1,2-diol + NAD+. HAMAP MF_01649

Pathway

Aromatic compound metabolism; 3-phenylpropanoate degradation. HAMAP MF_01649

Subunit structure

This dioxygenase system consists of four proteins: the two subunits of the hydroxylase component (hcaE and hcaF), a ferredoxin (hcaC) and a ferredoxin reductase (hcaD) By similarity. HAMAP MF_01649

Sequence similarities

Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family. HAMAP MF_01649

Sequences

Sequence LengthMass (Da)Tools
C6UBE6 [UniParc].

Last modified September 22, 2009. Version 1.
Checksum: 58203B22B5D97554

FASTA17220,565
        10         20         30         40         50         60 
MSAQVSLELH HRISQFLFHE ASLLDDWKFR DWLAQLDEEI RYTMRTTVNA QTRDRRKGVQ 

        70         80         90        100        110        120 
PPTTWIFNDT KDQLERRIAR LETGMAWAEE PPSRTRHLIS NCQVSETDIP NVFAVRVNYL 

       130        140        150        160        170 
LYRAQKERDE TFYVGTRFDK VRRLEDDNWR LLERDIVLDQ AVITSHNLSV LF

« Hide

References

[1]"Genome sequences of Escherichia coli B strains REL606 and BL21(DE3)."
Jeong H., Barbe V., Lee C.H., Vallenet D., Yu D.S., Choi S.H., Couloux A., Lee S.W., Yoon S.H., Cattolico L., Hur C.G., Park H.S., Segurens B., Kim S.C., Oh T.K., Lenski R.E., Studier F.W., Daegelen P., Kim J.F.
J. Mol. Biol. 394:644-652(2009) [PubMed: 19786035] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000819 Genomic DNA. Translation: ACT40085.1.
RefSeqYP_003045621.1. NC_012967.1.

3D structure databases

ProteinModelPortalC6UBE6.
SMRC6UBE6. Positions 2-172.
ModBaseSearch...

Protein-protein interaction databases

STRINGC6UBE6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBESCT00000163084; EBESCP00000152330; EBESCG00000161729.
GeneID8176876.
GenomeReviewsGene locus ECB_02431 in contig CP000819_GR.
KEGGebr:ECB_02431.
PATRIC18237072. VBIEscCol118196_2549.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000011518.
ProtClustDBPRK10069.

Family and domain databases

HAMAPMF_01649. HcaF.
[Tree]
InterProIPR023712. HcaF.
IPR000391. Rng_hydr_dOase-bsu.
[Graphical view]
KOK05709.
PfamPF00866. Ring_hydroxyl_B. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC6UBE6_ECOBR
AccessionPrimary (citable) accession number: C6UBE6
Entry history
Integrated into UniProtKB/TrEMBL: September 22, 2009
Last sequence update: September 22, 2009
Last modified: December 14, 2011
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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