C6U9M5 (C6U9M5_BURPS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
ATP synthase subunit alpha RuleBase RU003552

Gene names

Name:	atpA_2 EMBL EET04311.1
ORF Names:	BURPS1710A_A1921 EMBL EET04311.1

Organism

Burkholderia pseudomallei 1710a EMBL EET04311.1

Taxonomic identifier

320371 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length	664 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function

Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit By similarity. RuleBase RU003552

Subunit structure

F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a1, b2 and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF1 is attached to CF0 by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains By similarity. RuleBase RU003552

Ontologies

Keywords
Biological process	ATP synthesis
Cellular component	CF(1) RuleBase RU003552
Ligand	ATP-binding RuleBase RU003552 Nucleotide-binding
Molecular function	Hydrolase RuleBase RU003552 EMBL EET04311.1
Gene Ontology (GO)
Biological process	ATP hydrolysis coupled proton transport Inferred from electronic annotation. Source: InterPro ATP synthesis coupled proton transport Inferred from electronic annotation. Source: InterPro
Cellular component	proton-transporting ATP synthase complex, catalytic core F(1) Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW hydrogen ion transporting ATP synthase activity, rotational mechanism Inferred from electronic annotation. Source: InterPro proton-transporting ATPase activity, rotational mechanism Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C6U9M5 [UniParc]. Last modified September 22, 2009. Version 1. Checksum: 0A28A7F7A7902C38	FASTA	664	69,646
	10 20 30 40 50 60 MTPTPDAPAA ADAATGAGWL ARRRGALARV ALAPVAQAIG RVERVADGIA FVSGLEDTML 70 80 90 100 110 120 NEVLRFEGGV TGFAHTLDED LISVVLLDPD AGVRAQTAVA RTGAVLEVPA GPQLLGRVVD 130 140 150 160 170 180 PLGRPLDGGA PLDAAHTLPI ERAAPAIIER DLVSEPLDTG VLIVDALFTI GRGQRELIIG 190 200 210 220 230 240 DRATGKTSLA IDAIVNQRHS DVICVYVAIG QRASAVRRVI DAVRRYGAPE RCVFVVAPAA 250 260 270 280 290 300 CAPGLQWIAP FAGFSIAEYF RDRGQHALVV VDDLTKHAAT HRELALLTRE PPGREAYPGD 310 320 330 340 350 360 IFYVHARLLE RAAKLSAALG GGSLSALPIA ETDAGNLAAY IPTNLISITD GQIVLDSALF 370 380 390 400 410 420 AANQRPAVDV GLSVSRVGGK AQHPALRAAS GRLRLDYAQF LELEAFTRFG GLTDARLRAQ 430 440 450 460 470 480 ITRGERIRAL ITQPRFRALR TLDEVVLLKA LAAGALDAMS PDLVAPLRER LPAWLDARIA 490 500 510 520 530 540 ALTPALAPPR DWLADDAALD ALAESVGELI ERIAADAARR ATAGMPAEDA AGDIGGAFGG 550 560 570 580 590 600 EQARGDADRD ADHGANREVS REVSPEASRE VSREVSCEVS HEADRDAAAD AARVAGRAPG 610 620 630 640 650 660 RAEPDRAAPR AMPDGPPRAQ ADGDRASASR PRPDARGDAA RTAPSPQGGA DANVDAEAEA RHKR

References

[1]	Harkins D.M., DeShazer D., Woods D.E., Brinkac L.M., Brown K.A., Hung G.C., Tuanyok A., Zhang B., Nierman W.C. Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: 1710a EMBL EET04311.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CM000833 Genomic DNA. Translation: EET04311.1.
3D structure databases
ProteinModelPortal	C6U9M5.
SMR	C6U9M5. Positions 37-476.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
PATRIC	27847927. VBIBurPse76422_5435.
Family and domain databases
HAMAP	MF_01346. ATP_synth_alpha_bact. [Tree]
InterPro	IPR020003. ATPase_a/bsu_AS. IPR005294. ATPase_F1-cplx_asu. IPR018118. ATPase_F1/A1-cplx_a/bsu_N. IPR023366. ATPase_F1/A1-cplx_a_su_N. IPR000793. ATPase_F1/V1/A1-cplx_a/bsu_C. IPR004100. ATPase_F1/V1/A1-cplx_a/bsu_N. IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd. [Graphical view]
Gene3D	G3DSA:2.40.30.20. G3DSA:2.40.30.20. 1 hit.
PANTHER	PTHR15184:SF3. ATPase_F1_a. 1 hit.
Pfam	PF00006. ATP-synt_ab. 1 hit. PF00306. ATP-synt_ab_C. 1 hit. PF02874. ATP-synt_ab_N. 1 hit. [Graphical view]
SUPFAM	SSF47917. ATPase_a/b_C. 1 hit. SSF50615. ATPase_a/b_N. 1 hit.
TIGRFAMs	TIGR00962. AtpA. 1 hit.
PROSITE	PS00152. ATPASE_ALPHA_BETA. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C6U9M5_BURPS

Accession

Primary (citable) accession number: C6U9M5

Entry history

Integrated into UniProtKB/TrEMBL:	September 22, 2009
Last sequence update:	September 22, 2009
Last modified:	December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)