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C6TUI2 (C6TUI2_BURPS) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
N-succinylglutamate 5-semialdehyde dehydrogenase HAMAP MF_01174
EC=1.2.1.71 HAMAP MF_01174
Alternative name(s):
Succinylglutamic semialdehyde dehydrogenase HAMAP MF_01174
Gene names
Name:astD HAMAP MF_01174 EMBL EET06888.1
ORF Names:BURPS1710A_3282 EMBL EET06888.1
OrganismBurkholderia pseudomallei 1710a EMBL EET06888.1
Taxonomic identifier320371 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group

Protein attributes

Sequence length487 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate By similarity. HAMAP MF_01174 SAAS SAAS017649

Catalytic activity

N-succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O = N-succinyl-L-glutamate + NADH. HAMAP MF_01174 SAAS SAAS017649

Pathway

Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 4/5. HAMAP MF_01174 SAAS SAAS017649

Sequence similarities

Belongs to the aldehyde dehydrogenase family. AstD subfamily. HAMAP MF_01174

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding221 – 2266NAD By similarity HAMAP MF_01174

Sites

Active site2441 By similarity HAMAP MF_01174
Active site2781 By similarity HAMAP MF_01174

Sequences

Sequence LengthMass (Da)Tools
C6TUI2 [UniParc].

Last modified September 22, 2009. Version 1.
Checksum: DB57627D1A743BA2

FASTA48751,839
        10         20         30         40         50         60 
MTELFIDGAW RDGAGPVFAS RNPGTGEPVW EGAGASADDV ERAVASARRA FAAWSALDLD 

        70         80         90        100        110        120 
ARCAIVKRFA ALLVERKEAL ATMIGRETGK PLWEARTEVA SMAAKVDVSI AAYHERTGER 

       130        140        150        160        170        180 
RSPTADGVAV LRHRPHGVVA VFGPYNFPGH LPNGHIVPAL IAGNTVVFKP SELAPGVARA 

       190        200        210        220        230        240 
TVEIWRDAGL PAGVLNLVQG EKDTGVALAN HRQIDGLFFT GSSDTGTLLH RQFGGRPEIV 

       250        260        270        280        290        300 
LALEMGGNNP LVVADVEDID AAVHHAIQSA FLSAGQRCTC ARRILVPRGA FGDRFLERFA 

       310        320        330        340        350        360 
DVASRITADV YDADPQPFMG AVISARAASR LVAAQAKLLE LGAAPIIEMR QRDPALGFVN 

       370        380        390        400        410        420 
ASILDVTPVR ELPDEEHFGP LAQIVRYTDL DDAIARANDT AFGLSAGLLA DDETVWNTFR 

       430        440        450        460        470        480 
RAIRAGIVNW NRPTNGASSA APFGGAGRSG NHRPSAYYAA DYCAYPMASV ESAQLQMPAN 


LSPGLHF

« Hide

References

[1]Harkins D.M., DeShazer D., Woods D.E., Brinkac L.M., Brown K.A., Hung G.C., Tuanyok A., Zhang B., Nierman W.C.
Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: 1710a EMBL EET06888.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CM000832 Genomic DNA. Translation: EET06888.1.

3D structure databases

ProteinModelPortalC6TUI2.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

PATRIC27842689. VBIBurPse76422_2674.

Phylogenomic databases

OMAMTQRDPR.

Family and domain databases

HAMAPMF_01174. Aldedh_AstD.
[Tree]
InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR017649. SuccinylGlu_semiald_DH_AstD.
[Graphical view]
Gene3DG3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit.
G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
PANTHERPTHR11699:SF24. PTHR11699:SF24. 1 hit.
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMSSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMsTIGR03240. Arg_catab_astD. 1 hit.
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC6TUI2_BURPS
AccessionPrimary (citable) accession number: C6TUI2
Entry history
Integrated into UniProtKB/TrEMBL: September 22, 2009
Last sequence update: September 22, 2009
Last modified: December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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