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C6TUB9 (C6TUB9_BURPS) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 15. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Imidazolonepropionase HAMAP MF_00372

EC=3.5.2.7 HAMAP MF_00372
Alternative name(s):
Imidazolone-5-propionate hydrolase HAMAP MF_00372
Gene names
Name:hutI HAMAP MF_00372 EMBL EET07499.1
ORF Names:BURPS1710A_3219 EMBL EET07499.1
OrganismBurkholderia pseudomallei 1710a EMBL EET07499.1
Taxonomic identifier320371 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group

Protein attributes

Sequence length407 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate + H2O = N-formimidoyl-L-glutamate + H+. HAMAP MF_00372 SAAS SAAS005920

Cofactor

Binds 1 zinc or iron ion per subunit By similarity. HAMAP MF_00372 SAAS SAAS005920

Pathway

Amino-acid degradation; L-histidine degradation into L-glutamate; N-formimidoyl-L-glutamate from L-histidine: step 3/3. HAMAP MF_00372 SAAS SAAS005920

Subcellular location

Cytoplasm By similarity HAMAP MF_00372.

Sequence similarities

Belongs to the hutI family. HAMAP MF_00372

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding681Zinc or iron By similarity HAMAP MF_00372
Metal binding701Zinc or iron By similarity HAMAP MF_00372
Metal binding2381Zinc or iron By similarity HAMAP MF_00372
Metal binding3131Zinc or iron By similarity HAMAP MF_00372
Binding site771Substrate By similarity HAMAP MF_00372
Binding site901Substrate By similarity HAMAP MF_00372
Binding site1401Substrate By similarity HAMAP MF_00372
Binding site1731Substrate By similarity HAMAP MF_00372
Binding site2411Substrate By similarity HAMAP MF_00372

Sequences

Sequence LengthMass (Da)Tools
C6TUB9 [UniParc].

Last modified September 22, 2009. Version 1.
Checksum: 0D598C798DB8E369

FASTA40743,787
        10         20         30         40         50         60 
MKSILWHNLK LCAHGDPNDT IADAAIAVNG DGTIAWTGRA SDVPAGYVHW PREDLRGAWV 

        70         80         90        100        110        120 
TPGLVDCHTH LVYGGQRADE FAQRLAGASY EEIAQRGGGI VSTVRATRDA SEAALFEQAC 

       130        140        150        160        170        180 
ARLRPLLAEG VTAIEIKSGY GLELASERRM LRVARQLGER FPVSVYTTFL GAHALPPEYA 

       190        200        210        220        230        240 
GRADEYIDEV CERMLPALAD EGLVDAVDVF CERIGFTLAQ SERVFEAAAR RGLPVKMHAE 

       250        260        270        280        290        300 
QLSNGGGSAL AARYRALSAD HLEYLDAAGV AAMRASGTTA VLLPGAYYFI RETKLPPIDL 

       310        320        330        340        350        360 
LRRHGVPIAL ATDHNPGTSP LTSLLLTMNM GCTVFKLTVQ EALLGVTRHA AAALGASDRH 

       370        380        390        400 
GSLAPGRQAD FAVWPVSTLA ELAYWFGRPL CERVVKGGVT VFTRDAR 

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References

[1]Harkins D.M., DeShazer D., Woods D.E., Brinkac L.M., Brown K.A., Hung G.C., Tuanyok A., Zhang B., Nierman W.C.
Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: 1710a EMBL EET07499.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CM000832 Genomic DNA. Translation: EET07499.1.

3D structure databases

ProteinModelPortalC6TUB9.
SMRC6TUB9. Positions 3-399.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

PATRIC27842569. VBIBurPse76422_2614.

Phylogenomic databases

OMAMNMACTL.

Family and domain databases

HAMAPMF_00372. HutI.
[Tree]
InterProIPR006680. Amidohydro_1.
IPR005920. HutI.
IPR011059. Metal-dep_hydrolase_composite.
[Graphical view]
PANTHERPTHR22642. PTHR22642. 1 hit.
PfamPF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMSSF51338. Metalo_hydrolase. 1 hit.
TIGRFAMsTIGR01224. HutI. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC6TUB9_BURPS
AccessionPrimary (citable) accession number: C6TUB9
Entry history
Integrated into UniProtKB/TrEMBL: September 22, 2009
Last sequence update: September 22, 2009
Last modified: December 14, 2011
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)