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C6SRH2

- C6SRH2_STRMN

UniProt

C6SRH2 - C6SRH2_STRMN

Protein

Elongation factor Tu

Gene

tuf

Organism
Streptococcus mutans serotype c (strain NN2025)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 39 (01 Oct 2014)
      Sequence version 1 (22 Sep 2009)
      Previous versions | rss
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    Functioni

    This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi19 – 268GTPUniRule annotation
    Nucleotide bindingi84 – 885GTPUniRule annotation
    Nucleotide bindingi139 – 1424GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-HAMAP
    3. translation elongation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Elongation factorUniRule annotationImported

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciSMUT511691:GH9C-1345-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tufUniRule annotationImported
    Ordered Locus Names:SmuNN2025_1288Imported
    OrganismiStreptococcus mutans serotype c (strain NN2025)Imported
    Taxonomic identifieri511691 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
    ProteomesiUP000007704: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    PTM / Processingi

    Proteomic databases

    PRIDEiC6SRH2.

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliC6SRH2.
    SMRiC6SRH2. Positions 2-396.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.UniRule annotation
    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000229290.
    KOiK02358.
    OMAiGTEMCMP.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. EFACTOR_GTP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C6SRH2-1 [UniParc]FASTAAdd to Basket

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    MAKEKYDRSK PHVNIGTIGH VDHGKTTLTA AITTVLARRL PSAVNQPKDY    50
    SSIDAAPEER ERGITINTAH VEYETEKRHY AHIDAPGHAD YVKNMITGAA 100
    QMDGAILVVA STDGPMPQTR EHILLSRQVG VKYLIVFMNK VDLVDDEELL 150
    ELVEMEIRDL LSEYDFPGDD IPVIQGSALK ALEGDTAQED IIMELMHTVD 200
    DYIPDPERDT DKPLLLPVED VFSITGRGTV ASGRIDRGTV KVNDEVEIVG 250
    IRDDIQKAVV TGVEMFRKQL DEGIAGDNVG VLLRGIQRDE IERGQVLAKP 300
    GSIHPHTKFK GEVYILTKEE GGRHTPFFNN YRPQFYFRTT DVTGSIELPA 350
    GTEMVMPGDN VTIDVELIHP IAVEQGTTFS IREGGRTVGS GIVSEIEA 398
    Length:398
    Mass (Da):43,919
    Last modified:September 22, 2009 - v1
    Checksum:i660548E674C6DF9D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP010655 Genomic DNA. Translation: BAH88314.1.
    RefSeqiYP_003485206.1. NC_013928.1.

    Genome annotation databases

    EnsemblBacteriaiBAH88314; BAH88314; SmuNN2025_1288.
    GeneIDi8835017.
    KEGGismc:SmuNN2025_1288.
    PATRICi35314472. VBIStrMut11111_1288.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AP010655 Genomic DNA. Translation: BAH88314.1 .
    RefSeqi YP_003485206.1. NC_013928.1.

    3D structure databases

    ProteinModelPortali C6SRH2.
    SMRi C6SRH2. Positions 2-396.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi C6SRH2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAH88314 ; BAH88314 ; SmuNN2025_1288 .
    GeneIDi 8835017.
    KEGGi smc:SmuNN2025_1288.
    PATRICi 35314472. VBIStrMut11111_1288.

    Phylogenomic databases

    HOGENOMi HOG000229290.
    KOi K02358.
    OMAi GTEMCMP.

    Enzyme and pathway databases

    BioCyci SMUT511691:GH9C-1345-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. EFACTOR_GTP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Comparative genomic analyses of Streptococcus mutans provide insights into chromosomal shuffling and species-specific content."
      Maruyama F., Kobata M., Kurokawa K., Nishida K., Sakurai A., Nakano K., Nomura R., Kawabata S., Ooshima T., Nakai K., Hattori M., Hamada S., Nakagawa I.
      BMC Genomics 10:358-358(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: NN2025Imported.

    Entry informationi

    Entry nameiC6SRH2_STRMN
    AccessioniPrimary (citable) accession number: C6SRH2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 22, 2009
    Last sequence update: September 22, 2009
    Last modified: October 1, 2014
    This is version 39 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3