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Protein
Submitted name:

Putative trypsinogen

Gene

try

Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protease, Serine proteaseUniRule annotation

Enzyme and pathway databases

ReactomeiR-SSC-1442490 Collagen degradation
R-SSC-1592389 Activation of Matrix Metalloproteinases
R-SSC-196741 Cobalamin (Cbl, vitamin B12) transport and metabolism
R-SSC-6798695 Neutrophil degranulation
R-SSC-6803157 Antimicrobial peptides

Protein family/group databases

MEROPSiS01.120

Names & Taxonomyi

Protein namesi
Submitted name:
Putative trypsinogenImported
Gene namesi
Name:tryImported
Synonyms:PRSS2Imported
OrganismiSus scrofa (Pig)Imported
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus
Proteomesi
  • UP000008227 Componenti: Chromosome 18

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 15Sequence analysisAdd BLAST15
ChainiPRO_501456904616 – 247Sequence analysisAdd BLAST232

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSSSCG00000016478

Interactioni

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000017461

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini24 – 244Peptidase S1InterPro annotationAdd BLAST221

Sequence similaritiesi

Belongs to the peptidase S1 family.SAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3627 Eukaryota
COG5640 LUCA
GeneTreeiENSGT00760000118862
KOiK01312
OMAiSALPWIN
OrthoDBiEOG091G0DF7
TreeFamiTF331065

Family and domain databases

CDDicd00190 Tryp_SPc, 1 hit
InterProiView protein in InterPro
IPR009003 Peptidase_S1_PA
IPR001314 Peptidase_S1A
IPR001254 Trypsin_dom
IPR018114 TRYPSIN_HIS
IPR033116 TRYPSIN_SER
PfamiView protein in Pfam
PF00089 Trypsin, 1 hit
PRINTSiPR00722 CHYMOTRYPSIN
SMARTiView protein in SMART
SM00020 Tryp_SPc, 1 hit
SUPFAMiSSF50494 SSF50494, 1 hit
PROSITEiView protein in PROSITE
PS50240 TRYPSIN_DOM, 1 hit
PS00134 TRYPSIN_HIS, 1 hit
PS00135 TRYPSIN_SER, 1 hit

Sequencei

Sequence statusi: Complete.

C6L245-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNPLLILACI GAAVAFPTDD DDKIVGGYTC AANSVPYQVS LNSGYHFCGG
60 70 80 90 100
SLISDQWVVS AAHCYKSRIQ VRLGENNIDV LEGDEQFIDA AKIIRHPKYN
110 120 130 140 150
SWTLDNDILL IKLSSPAVLN SRVSTLALPS ACAPAGTLCL ISGWGNTLSS
160 170 180 190 200
GVNYPELLQC LDAPLLSQAE CEASYPGEIT SNMVCAGFLE GGKDSCQGDS
210 220 230 240
GGPVACNGQL QGIVSWGYGC AQKNRPGVYT KVCNYVDWIQ QTIAANS
Length:247
Mass (Da):26,178
Last modified:September 22, 2009 - v1
Checksum:iD0EA90A301324BAC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AEMK02000111 Genomic DNA No translation available.
AB476299 Genomic DNA Translation: BAH86963.1
AB476300 Genomic DNA Translation: BAH86994.1
RefSeqiNP_001193367.1, NM_001206438.1
UniGeneiSsc.25371

Genome annotation databases

EnsembliENSSSCT00000017942; ENSSSCP00000017461; ENSSSCG00000016478
GeneIDi100525899
KEGGissc:100525899

Similar proteinsi

Entry informationi

Entry nameiC6L245_PIG
AccessioniPrimary (citable) accession number: C6L245
Entry historyiIntegrated into UniProtKB/TrEMBL: September 22, 2009
Last sequence update: September 22, 2009
Last modified: May 23, 2018
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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