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Protein
Submitted name:

Putative trypsinogen

Gene

try

Organism
Sus scrofa (Pig)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Serine proteaseUniRule annotationSAAS annotation

Enzyme and pathway databases

ReactomeiR-SSC-1442490. Collagen degradation.
R-SSC-1592389. Activation of Matrix Metalloproteinases.
R-SSC-196741. Cobalamin (Cbl, vitamin B12) transport and metabolism.

Protein family/group databases

MEROPSiS01.120.

Names & Taxonomyi

Protein namesi
Submitted name:
Putative trypsinogenImported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:tryImported
Synonyms:PRSS2Imported
OrganismiSus scrofa (Pig)
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus
Proteomesi
  • UP000008227 Componenti: Chromosome 18

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PeptideAtlasiC6L245.

Interactioni

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000017461.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini24 – 244221Peptidase S1InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the peptidase S1 family.SAAS annotation
Contains 1 peptidase S1 domain.UniRule annotation

Phylogenomic databases

eggNOGiKOG3627. Eukaryota.
COG5640. LUCA.
GeneTreeiENSGT00760000118862.
KOiK01312.
OMAiKVCNFVD.
OrthoDBiEOG091G0DF7.
TreeFamiTF331065.

Family and domain databases

CDDicd00190. Tryp_SPc. 1 hit.
InterProiIPR009003. Peptidase_S1_PA.
IPR001314. Peptidase_S1A.
IPR001254. Trypsin_dom.
IPR018114. TRYPSIN_HIS.
IPR033116. TRYPSIN_SER.
[Graphical view]
PfamiPF00089. Trypsin. 1 hit.
[Graphical view]
PRINTSiPR00722. CHYMOTRYPSIN.
SMARTiSM00020. Tryp_SPc. 1 hit.
[Graphical view]
SUPFAMiSSF50494. SSF50494. 1 hit.
PROSITEiPS50240. TRYPSIN_DOM. 1 hit.
PS00134. TRYPSIN_HIS. 1 hit.
PS00135. TRYPSIN_SER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C6L245-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNPLLILACI GAAVAFPTDD DDKIVGGYTC AANSVPYQVS LNSGYHFCGG
60 70 80 90 100
SLISDQWVVS AAHCYKSRIQ VRLGENNIDV LEGDEQFIDA AKIIRHPKYN
110 120 130 140 150
SWTLDNDILL IKLSSPAVLN SRVSTLALPS ACAPAGTLCL ISGWGNTLSS
160 170 180 190 200
GVNYPELLQC LDAPLLSQAE CEASYPGEIT SNMVCAGFLE GGKDSCQGDS
210 220 230 240
GGPVACNGQL QGIVSWGYGC AQKNRPGVYT KVCNYVDWIQ QTIAANS
Length:247
Mass (Da):26,178
Last modified:September 22, 2009 - v1
Checksum:iD0EA90A301324BAC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU655925 Genomic DNA. No translation available.
AB476299 Genomic DNA. Translation: BAH86963.1.
AB476300 Genomic DNA. Translation: BAH86994.1.
RefSeqiNP_001193367.1. NM_001206438.1.
UniGeneiSsc.25371.

Genome annotation databases

EnsembliENSSSCT00000017942; ENSSSCP00000017461; ENSSSCG00000016478.
GeneIDi100525899.
KEGGissc:100525899.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU655925 Genomic DNA. No translation available.
AB476299 Genomic DNA. Translation: BAH86963.1.
AB476300 Genomic DNA. Translation: BAH86994.1.
RefSeqiNP_001193367.1. NM_001206438.1.
UniGeneiSsc.25371.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000017461.

Protein family/group databases

MEROPSiS01.120.

Proteomic databases

PeptideAtlasiC6L245.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSSSCT00000017942; ENSSSCP00000017461; ENSSSCG00000016478.
GeneIDi100525899.
KEGGissc:100525899.

Organism-specific databases

CTDi5645.

Phylogenomic databases

eggNOGiKOG3627. Eukaryota.
COG5640. LUCA.
GeneTreeiENSGT00760000118862.
KOiK01312.
OMAiKVCNFVD.
OrthoDBiEOG091G0DF7.
TreeFamiTF331065.

Enzyme and pathway databases

ReactomeiR-SSC-1442490. Collagen degradation.
R-SSC-1592389. Activation of Matrix Metalloproteinases.
R-SSC-196741. Cobalamin (Cbl, vitamin B12) transport and metabolism.

Family and domain databases

CDDicd00190. Tryp_SPc. 1 hit.
InterProiIPR009003. Peptidase_S1_PA.
IPR001314. Peptidase_S1A.
IPR001254. Trypsin_dom.
IPR018114. TRYPSIN_HIS.
IPR033116. TRYPSIN_SER.
[Graphical view]
PfamiPF00089. Trypsin. 1 hit.
[Graphical view]
PRINTSiPR00722. CHYMOTRYPSIN.
SMARTiSM00020. Tryp_SPc. 1 hit.
[Graphical view]
SUPFAMiSSF50494. SSF50494. 1 hit.
PROSITEiPS50240. TRYPSIN_DOM. 1 hit.
PS00134. TRYPSIN_HIS. 1 hit.
PS00135. TRYPSIN_SER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiC6L245_PIG
AccessioniPrimary (citable) accession number: C6L245
Entry historyi
Integrated into UniProtKB/TrEMBL: September 22, 2009
Last sequence update: September 22, 2009
Last modified: September 7, 2016
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.