C6KXN3 (C6KXN3_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lambda light chain of human immunoglobulin surface antigen-related protein EMBL BAH86638.1

Gene names

Name:

IgLC-rG EMBL BAH86638.1

Organism

Homo sapiens (Human) EMBL BAH86638.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	232 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

Ontologies

Keywords
Technical term	3D-structure PDB 4AIX PDB 4AJ0
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL BAH86638.1
	Non-terminal residue	232	1	EMBL BAH86638.1

Sequences

	Sequence		Length	Mass (Da)
	C6KXN3 [UniParc]. Last modified September 22, 2009. Version 1. Checksum: 3DF77E9EE174E1EA	FASTA	232	24,742
	10 20 30 40 50 60 MAWIPLFLGV LAYCTGSVAS YELTQPPLVS VSPGQTASIT CSGDKLGDNY ACWYQLKPGQ 70 80 90 100 110 120 SPVLVIYQDN RRPSGIPERI SGSNSGNTAT LTISGTQAMD EAEYYCQAWD SSTSWVFGGG 130 140 150 160 170 180 TKLTVLGQPK AAPSVTLFPP SSEELQANKA TLVCLISDFY PGAVTVAWKA DSSPVKAGVE 190 200 210 220 230 TTTPSKQSNN KYAASSYLSL TPEQWKSHRS YSCQVTHEGS TVEKTVAPTE CS

References

[1]	"Activation of cyclosporin A transport by a novel lambda light chain of human Ig surface antigen-related gene in Xenopus laevis oocytes." Kobayashi Y., Umemoto T., Ohbayashi M., Kohyama N., Sanada Y., Yamamoto T. Drug Metab. Dispos. 38:1427-1435(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Light Chain Amyloidosis Lambda 3 and Lambda 6 Two Different Stories of the Same Phenomenom." Villalba M.I., Luna O.D., Rudino-Pinera E., Sanchez R., Sanchez-Lopez R., Rojas-Trejo S., Olamendi-Portugal T., Fernandez-Velasco D.A., Becerril B. Submitted (FEB-2012) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS) OF 20-126.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AB369252 mRNA. Translation: BAH86638.1.

IPI

IPI00972963.

UniGene

Hs.449585.
Hs.625768.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
4AIX	X-ray	1.80	A/B/C/D	20-126	[»]
4AJ0	X-ray	1.70	A/B/C/D	20-126	[»]

ProteinModelPortal

C6KXN3.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Phylogenomic databases

HOGENOM

HOG000059537.

Family and domain databases

Gene3D

2.60.40.10. 2 hits.

InterPro

IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
[Graphical view]

Pfam

PF07654. C1-set. 1 hit.
PF07686. V-set. 1 hit.
[Graphical view]

SMART

SM00407. IGc1. 1 hit.
SM00406. IGv. 1 hit.
[Graphical view]

PROSITE

PS50835. IG_LIKE. 2 hits.
PS00290. IG_MHC. 1 hit.
[Graphical view]

ProtoNet

Search...

Other

NextBio

35483348.

Entry information

Entry name

C6KXN3_HUMAN

Accession

Primary (citable) accession number: C6KXN3

Entry history

Integrated into UniProtKB/TrEMBL:	September 22, 2009
Last sequence update:	September 22, 2009
Last modified:	May 1, 2013
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.