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Protein
Submitted name:

Cullin-like protein, putative

Gene

PF3D7_0629800

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

  • G1/S transition of mitotic cell cycle Source: GeneDB
  • protein ubiquitination Source: GOC
  • regulation of cell cycle Source: GeneDB
  • ubiquitin-dependent protein catabolic process Source: InterPro

Enzyme and pathway databases

ReactomeiR-PFA-68949 Orc1 removal from chromatin
R-PFA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
R-PFA-917937 Iron uptake and transport
R-PFA-983168 Antigen processing: Ubiquitination & Proteasome degradation

Names & Taxonomyi

Protein namesi
Submitted name:
Cullin-like protein, putativeImported
Gene namesi
ORF Names:PF3D7_0629800Imported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_0629800

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Proteomic databases

PRIDEiC6KTD3

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliC6KTD3
SMRiC6KTD3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini683 – 1007CULLIN_2InterPro annotationAdd BLAST325

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili218 – 238Sequence analysisAdd BLAST21
Coiled coili871 – 891Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the cullin family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

HOGENOMiHOG000281645
InParanoidiC6KTD3
OMAiCKRLIND

Family and domain databases

InterProiView protein in InterPro
IPR016158 Cullin_homology
IPR036317 Cullin_homology_sf
IPR001373 Cullin_N
IPR019559 Cullin_neddylation_domain
IPR016159 Cullin_repeat-like_dom_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF00888 Cullin, 3 hits
SMARTiView protein in SMART
SM00182 CULLIN, 1 hit
SM00884 Cullin_Nedd8, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
SSF74788 SSF74788, 2 hits
SSF75632 SSF75632, 2 hits
PROSITEiView protein in PROSITE
PS50069 CULLIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

C6KTD3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDPTAVNNYP VFYVKNKDFL NVDNEHIRCS LKRFEEYIHE CFSILPYNKI
60 70 80 90 100
KIQNEEKISV QHFCDVLVFN QCEQIICAII EKECNEKTKQ FFEEVEIRIK
110 120 130 140 150
NEEFKNGEEE FLKLFVSIWN NFSLVLIHIS DILQSFIAYT KNMCCNFFDP
160 170 180 190 200
TQIFNYLWKK YINQYVIIKN MFISSICNYL TYDKIYCETY FYEYVCVNIC
210 220 230 240 250
NKYATKRYNL KKNQINYIER LQNIQKNYQV NNEATNKQTN KINKKDCINK
260 270 280 290 300
KEIPTENITY KTKEEEHIQR GDHNNNNNYN NSYDNNNYSD DIYNSNPYLD
310 320 330 340 350
DTNHEYKNTQ KKKKINDKVL SLSIKISDIL NLYDDFERIY KNETYTFYKE
360 370 380 390 400
KIEKYKKDME TLGYEECNFD FPIIVENYLC HEQIRSRKFL KEHTEITILN
410 420 430 440 450
MLKDLLLVKN RDVLFKDSYI KYCIIKEKYD PLRSVYLYSL NLDDLENFSN
460 470 480 490 500
IFFNVVDNIG TELVNDVINK RNNSSLLNNA IIKLINFKLN VDRIIIMSFR
510 520 530 540 550
YSSYFMKKWR EVFEHFINKG IQAETYMPII LSMYLNNLLT MYNACLRKLK
560 570 580 590 600
KYYILNKKIK NNRSLFNNLL FEVDWNNYCT QPISETIDFY DISTDSDNML
610 620 630 640 650
GIKKYLRKKR KNTKKDLINF EHEEEYVKRK HMDNNIHNND HNDNIYFNNN
660 670 680 690 700
LYFNNDYHNN LYYDSLNINK RSDEKIFFHL LKIDKLFKKY HIIGKYIMNM
710 720 730 740 750
ITVILSLFRY VSDKEKFEKY YRTYMCKRLI NDSSFNIILD VKVFKTLKKE
760 770 780 790 800
CGAQFTKKIE IILKDMKFTS KTLMKFYKEL PNNVNHFLKR KKYAVNIIFN
810 820 830 840 850
ESWEYVNTEN NVIYPPMIKM CNEAFFLFYQ KYNKSKNIKF LPLLGLCTLR
860 870 880 890 900
VHFKNFKEEG SFDLGKRDDN NDEKRDDNND EKRDHNNIEK RDDNNIEKRD
910 920 930 940 950
DNNIEKRDDN NIEKRDDNND EKRDENNDKK RDENNNYSDD NDDDLNNEDS
960 970 980 990 1000
SSTYNKKGKK KIYITVTILQ ALVLLLFNKK NEYHINEIKE LTGISTENII
1010 1020 1030 1040 1050
RYLKTIYTIG ETHILIYDKA NEILKLNFSF RSKKKFLIVN YNDVLYKDDM
1060 1070 1080 1090 1100
GPTTSLLNED NEIEDKTLHI DAAIVKFLKT NGKSSERKIC SFIKDKMDIS
1110 1120
SNEQIKNRIS SLLSREFIFF KNNNYHYEL
Length:1,129
Mass (Da):136,343
Last modified:September 1, 2009 - v1
Checksum:iD94ABED21070BC6B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844505 Genomic DNA Translation: CAG25110.1
RefSeqiXP_966280.1, XM_961187.1

Genome annotation databases

EnsemblProtistsiCAG25110; CAG25110; PF3D7_0629800
GeneDBiPF3D7_0629800.1:pep
GeneIDi3885751
KEGGipfa:PFF1445c

Similar proteinsi

Entry informationi

Entry nameiC6KTD3_PLAF7
AccessioniPrimary (citable) accession number: C6KTD3
Entry historyiIntegrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: May 23, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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