C6KTD2 (HKNMT_PLAF7) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative histone-lysine N-methyltransferase PFF1440w
EC=2.1.1.43

Gene names

ORF Names:

PFF1440w

Organism

Plasmodium falciparum (isolate 3D7) [Reference proteome]

Taxonomic identifier

36329 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Alveolata › Apicomplexa › Aconoidasida › Haemosporida › Plasmodium › Plasmodium (Laverania) › Plasmodium falciparum

Protein attributes

Sequence length	6753 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Probable histone methyltransferase By similarity.
Catalytic activity	S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
Miscellaneous	Possible candidate for an effective malaria vaccine as determined by epitope response in sera. Ref.3
Sequence similarities	Contains 1 bromo domain. Contains 4 PHD-type zinc fingers. Contains 1 post-SET domain. Contains 1 RING-type zinc finger. Contains 1 SET domain.

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Developmental stage	Merozoite
Domain	Bromodomain Repeat Zinc-finger
Ligand	Metal-binding S-adenosyl-L-methionine Zinc
Molecular function	Chromatin regulator Methyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	histone lysine methylation Inferred from electronic annotation. Source: GOC regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	histone-lysine N-methyltransferase activity Inferred from electronic annotation. Source: EC protein domain specific binding Inferred from sequence or structural similarity Ref.2. Source: GeneDB_Pfalciparum zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 6753	6753	Putative histone-lysine N-methyltransferase PFF1440w		PRO_0000388753
Regions
	Domain	1832 – 1902	71	Bromo
	Domain	6611 – 6733	123	SET
	Domain	6737 – 6753	17	Post-SET
	Zinc finger	1671 – 1728	58	PHD-type 1
	Zinc finger	1761 – 1819	59	PHD-type 2
	Zinc finger	1764 – 1817	54	RING-type; degenerate
	Zinc finger	2510 – 2579	70	PHD-type 3
	Zinc finger	5557 – 5609	53	PHD-type 4; degenerate
	Compositional bias	66 – 6329	6264	Asn-rich
	Compositional bias	451 – 575	125	Lys-rich
	Compositional bias	843 – 1091	249	Lys-rich
	Compositional bias	1460 – 1591	132	Lys-rich
	Compositional bias	4196 – 4338	143	Lys-rich
	Compositional bias	5401 – 5520	120	Lys-rich

Sequences

	Sequence		Length	Mass (Da)
	C6KTD2 [UniParc]. Last modified September 1, 2009. Version 1. Checksum: EF689CABCFA20F00	FASTA	6,753	796,045
	10 20 30 40 50 60 MSENSDEGKM QKGKGNEMNE DKIICKKEES NSSSYKFISF IKTIEDVKEK WKSSNLSRMD 70 80 90 100 110 120 VLKLKNDDIN NDDNMNNMDN MNNMNNMNNI NNMNNMNNIN NMNNMNNINN MNNMNNMNNM 130 140 150 160 170 180 DNMNNNEKHP CSNNNYSFNN YIKESINYNT CTGYDKNNIM LNFLDKHKKS IFLKSRNNVN 190 200 210 220 230 240 TFQSDINSSK TSSFFSCMSL KNMNYHNDIN KYSNYRMMKN INGLHKLMIL KNKNKDKKLF 250 260 270 280 290 300 TNTSDKKNYY CLNNGDHIIN EKDSFSDTYI SYGCRKRRWK KKKKNIYNML FYDESINDYP 310 320 330 340 350 360 YKNLEKTTFS NSSKIYELFF NKYKKKKILN IECSGNKYKG LLRTNHFPPY ANFNFTIRRK 370 380 390 400 410 420 LQTSNVLGHF MISKCNFNRT ICYRKYIKCV NKYKNNKRNR VINMYVKKEN VDSIKGTFGN 430 440 450 460 470 480 MNNGVHHNNS RRRLNNTSKN NISNNNNNML KKKKGKKNYK GSFDQMIQED TTLDQAKKES 490 500 510 520 530 540 IKTVSKNERK NNMNKHSHDN KVSKLNKRMS NKRRNNKNCN PSNDMCNEDD VIEKICTTEE 550 560 570 580 590 600 VNDDEKKKKL SRHKKFVCER KKGVILQNNN KCKKKNDDNI INNNNDDVNN CGDNINDHHD 610 620 630 640 650 660 NRKDYDTTED QNKCPKILSI NFIKCDEKLF EKIYNDMFLR IGKIVTNKRK KYFLIYKIVK 670 680 690 700 710 720 DSFFRILILN TEKLEKNILQ VMAVQDVILC DKNVKIYSDP IYIRNNNKLY AIKFLKIFSL 730 740 750 760 770 780 KYMKKVKNMS EVNFSDDDEC KKENKDNISE SSKRSNNIGE KKMLHVEKSE EHDDMTSDSN 790 800 810 820 830 840 KEDTKIEEGR KKSNEVNIDV DDGEEEENVN NNDNNNDNNN DNDNSSDNNN NDDGSNDTES 850 860 870 880 890 900 CSKINKSKYK GKEKKDVKEN TDDKNLSDSN SNNSKKKFKV LNKAIKKDND KKKKYEKKNI 910 920 930 940 950 960 EGNSNNNMIL VRSNSSSTST SNSSSKSKSS NCRNKKNNQI SICSKMDEKN SEQKKKNIKK 970 980 990 1000 1010 1020 KNKTCNEGKS KKDSTKLNCV KKVKNKSTDK KNGKSKINIK NEKKKKINNS KINKGRKGIN 1030 1040 1050 1060 1070 1080 KKDKGKGDDN NYVCLIYDDE KKFYFNFKKF KDIINVIKGS DESTRFYVDT NNNNHNNNMK 1090 1100 1110 1120 1130 1140 KKMKLFKKVE KSLYLENLDI DTDEILFRRP KFFNCIIEES FENYDINYEG EDGNFYVFKN 1150 1160 1170 1180 1190 1200 KLNKIRKKVT IKNETDSSDM YIELKDEEKG FKYIGYRVSF ELKKDNKKKA QVKVGIIKYY 1210 1220 1230 1240 1250 1260 SPKYKQFFIH HLENYKLYQT SDLSKGNNNN NNNNMKENGF VKCGRNSYSR ACSKSLNSSI 1270 1280 1290 1300 1310 1320 YINKYKNVEL NEKITNIIDD DNNNNINSSC IYKNNLSNEN NLCADKVLCD GNYNMLENDV 1330 1340 1350 1360 1370 1380 DEMNNVDQNQ KKRNDLVFSD VKGWYSPYFY NIKILNNYKE FERFDILEKC DKKKEMTDHV 1390 1400 1410 1420 1430 1440 NNTLNKNEIC SICSKRILFM KGHDHYSCSL SSAIYDMCSE AEKKEIDENN CIDIYWGIKC 1450 1460 1470 1480 1490 1500 FTCEKKYHAN CLEDDVLITK WFDKNILMKE YKKFIYKNSL KKEKRYFNNN GKNKRTKNGK 1510 1520 1530 1540 1550 1560 KKKNTIHKLE DKNNSHVVST ASNSHSIEVS SSESAKKGNE KNTATCKKRK TSCSALYKKV 1570 1580 1590 1600 1610 1620 KKGKNKNGEN KNGENKNGDI KNDDIKNDDI KNDDIRNDDD KNDENEENTK ECKNESNNID 1630 1640 1650 1660 1670 1680 NNNSSNDSLS DVDNNKDNGK SKNKKYRRCI NYIPSVEHSD ITYKKFICKD CYRCIYCCES 1690 1700 1710 1720 1730 1740 IYDYKQTPNV ANYVICKNCN MVAHGSCCFP NVPDIYLFNW KCDDCLKCNK CNYSNLCYIN 1750 1760 1770 1780 1790 1800 YNEWELHLDC CINCYKEYEK KNFCIMCNEK YDEDDSKKWV QCDVCKFWIH LSCDKNESRN 1810 1820 1830 1840 1850 1860 IETLSNKNID YKCPTCSIGT FHDKIERILY LLFLLDKYKN FTFHVPINYS IYWRIVKIPM 1870 1880 1890 1900 1910 1920 NLYIMKKKIW EKKYDTILDF LYDFMLIIHN AKMVHMPNTP IYKNACIFEK KGRVIIKNMF 1930 1940 1950 1960 1970 1980 NMTNEYLNKC IEDCVENYKN EINNLDSFQI GHDNNNNNDN NINNNNKMEG VNNESVIFMN 1990 2000 2010 2020 2030 2040 DGCNNKLYNK EGTNMTCVNM DSINKNLNDM NNNNNNNNKM EVFCGQNNIK LNEYYINKEG 2050 2060 2070 2080 2090 2100 YNIISNDNNM NYDNYNNVQN IGMKKMYTNI NDYNSSNVPN ESVYNKENFI NNSSIYNINE 2110 2120 2130 2140 2150 2160 NNTYDLNCDK KLIFDNKYNL SAYQNEGDIM NYNGMYQKNI NISNPPYNNN NNNNNNMVKE 2170 2180 2190 2200 2210 2220 GEKYILNNDD MNNISISKDN DINNNCNNIA NIYRKRKLEQ YKKDITQYEL YELFDFKNDS 2230 2240 2250 2260 2270 2280 FFINRNKEMF SCSSNDHNLI DYNILYVKLN GKIYFNTFYD KHDEFDVCKI LKVHFLKNNR 2290 2300 2310 2320 2330 2340 RGGGNHIMCP KIRNNQNLKE DVTQCDEEKI EQNNDNGCDD EYDNNNNNNN NIGSSSISSI 2350 2360 2370 2380 2390 2400 NKIHMNDTYN NSINDNSLRH NNNCSVFINS NIFMIDVLNE KVKINNIVKE TKRIISPINN 2410 2420 2430 2440 2450 2460 VLKFLKCIQI VFFYDNNTNE CTEKEKNVIS SNLCNNNFEK YVNINSIDHN NMSGEKKRKS 2470 2480 2490 2500 2510 2520 VEEIMSVVDN KSYYGFNKCS EYILYSSNEY DRAKKKENKR IKLLKNDILK ECCYICGSIE 2530 2540 2550 2560 2570 2580 YKNNFIYCCI CGISVHYSCA NIVHPFLFNL NDYKDHKKEI NNILNIITRN FKCDNCIKCD 2590 2600 2610 2620 2630 2640 NCLLHFDSSL KHNLYFKLKN LNVSCNNNRM ERRTYNYLYD VKIKVFTTNK EGTKQTGKCV 2650 2660 2670 2680 2690 2700 MKTKENDIIK LDEDNKQKDE LNEANKECFY KQDDVHVEKN CDELLYKNSF NSEECNKNEK 2710 2720 2730 2740 2750 2760 KKNDNNVDEN DDNVDKNDDN NNNNNNGDDN NNIDNTLVDG DMNKLENDLN NSNDFSINEE 2770 2780 2790 2800 2810 2820 KKNNKDTKKY MISSKEEINK EIENVSNQMD NKNNDVDKKK NISNEEIILD NTKNSCHDND 2830 2840 2850 2860 2870 2880 SNVLYNESVK KSFNACKIEK KEGIEKDDNL GHVNKLRNKR LIKILSIREE GNKLVKCFCC 2890 2900 2910 2920 2930 2940 GKPSHDECFY IIDNNTYKNK ICTLKKTVKN YVRKKNVENK CNTKVEMNSD VILLDDNIKD 2950 2960 2970 2980 2990 3000 HCSVNKTGDE HMNNNEFIDI SKDKISEHNI LDESFNSGVV CSDKNRKDQV VFIDGDVKNN 3010 3020 3030 3040 3050 3060 DISIIEENVT YYTSKEVNNN SVLKNERDVE STSELYIGGD KHVYNKLETD NAEMESNNNN 3070 3080 3090 3100 3110 3120 NNNNNNSDCN NNVSTLSTAA VNTINRSHMS PQKNDNDMNK INQDDIIHTK MNDKKNVKDD 3130 3140 3150 3160 3170 3180 NGNMTNLNNN IDKNDRNLDT ILKEHSVIMQ KLDELKENRN KEHDGEFYNN LILNNQFLIH 3190 3200 3210 3220 3230 3240 SFKVEEGVEI NKDSIIINKK MFNKYILNKI YELLDNKKRV RIKDLFNLFN LDEFRCSFIL 3250 3260 3270 3280 3290 3300 YEVLNALNTY LNEKLKEYNL TKIRNGTYKK YENEIRNENF CLFNKYLIVN NRDKINITKV 3310 3320 3330 3340 3350 3360 VLKIQSLITE ILSDAMNGNI VDEKDKSKKK ESISSDFNVV NNVKEYNIQN GCINIDINNY 3370 3380 3390 3400 3410 3420 FKGEYINFKP ILCSSQFNLD TNAQIFLQNK ANLSMFQKSA SYNNNFENNL ENNFVNNKMN 3430 3440 3450 3460 3470 3480 NMNNMKNNMN NMNNIMNNIM NNNMNNIMNN IMNNNMNNII NNNNIFNNDV SNNVDMQHKS 3490 3500 3510 3520 3530 3540 DQICIFNSNN IHSVPIFNNK PYMDNNFNNM VLVNKSNDIN GDDILCNMKN LYNKSVCNKQ 3550 3560 3570 3580 3590 3600 EKNGYSVVHK NICDVNFPYN DTKIWNGDIT NKSKTYTYTN INNNGSVIDY RKWSSVNRSV 3610 3620 3630 3640 3650 3660 SMNNMNCIRS NTNPRILSGT DHILKNNHMN KRNNVNNTYG VNNVNNVNNV NNTNNVSCFM 3670 3680 3690 3700 3710 3720 MRRKIRSNSL HDMNDKMNKM NDNINININN LNIINNNINI CNMNYPIDRV DSMNNTFNRN 3730 3740 3750 3760 3770 3780 NIIISQNTKE NTNILNFNGN DFCNNNNNNN NIINKENNFG TSNFNSPFHV GNLAKSYSYN 3790 3800 3810 3820 3830 3840 NTMSEKNMNE VICPNVRNNM SNMNNMNNMN NMNNMNNMNN MNNMNNMDSI NNVISYSCTN 3850 3860 3870 3880 3890 3900 PNMKDINFNS MRRSSSTPKK STGLLKNYFN IDIDQYNKTN SHIMNYNVSI NNDMNNVYIN 3910 3920 3930 3940 3950 3960 NNNNHNNNNN NSCNNFINND VINMNNVGTF YNFNQNAESY NNISNNIKCS NINNIIINNN 3970 3980 3990 4000 4010 4020 MNVNNLNYFC NNKEVGFKEN DLNINQKVHT INKDPYEMNH SKMYVTFPYC NTKDNNSNKS 4030 4040 4050 4060 4070 4080 SLKSNVLRLD KIRNRNIKKP LLYNRSSSMH SSDNLIYNVH NNNRNSPAEF TSDIIINKER 4090 4100 4110 4120 4130 4140 NMENNYNTSI NYVNNNITNN IIVANNNCYH TANNFIQINY SPSSSNIVNI NKDSYKYDIS 4150 4160 4170 4180 4190 4200 LENCIDLGST NTCMYNLNNI HNKDINNMPL EDCFSHIGSC PNEQNEHEDE INEDNKKDVT 4210 4220 4230 4240 4250 4260 KQQKKRKLNS VSKKDMLIKK EMNADDNINC KENTLQNESP KKDDELREND LKTTTENIKS 4270 4280 4290 4300 4310 4320 NEVEDKEFVD KKKKRKLSVK VKVNVNVKVE LQDTENDENK EKGIKKEKND EEKKNDAEKK 4330 4340 4350 4360 4370 4380 KKENKKGREK SVKVRKTKNQ TQVERENEKE NLMENVTNDK TSDIINNKTS DIINNKTSDI 4390 4400 4410 4420 4430 4440 INNKTSDIIN NKTSDIINNK TSDIINNKTS DIINDKTNDI INNKTSDCLS LVQNNKPVIH 4450 4460 4470 4480 4490 4500 IDCNTSLDIT DGYNNLISCE GRKKGKYNIE ENNINDDNMF QYSDAFDSEG SIKYKEEYDK 4510 4520 4530 4540 4550 4560 IYIPNNKNKI NNINNFLIKN NLLLKSKFMR ITPNTYLCRN CVLLYQNDFS YNTYEEEINK 4570 4580 4590 4600 4610 4620 MERSILNEYE KGVIKKNEYV HDAIQNDKVV NTDENIMTNV LADKVDDMKI VEKLNCPLNV 4630 4640 4650 4660 4670 4680 EEKGIEENIL YVKREGDELI NYGKHNDQMK EEEESEVVLG DVDFLKNEKK DNLILPYDEK 4690 4700 4710 4720 4730 4740 YTGVNNNNSS IIMSLKKCDK NITKKKGKDK NFNNIKYFKI DNNKSLWYEN YMYWMNKISL 4750 4760 4770 4780 4790 4800 YNNLFFTNMY YKENVIKCID MNNLFLNKMN IYKCSICCML YHCSNMDRNN FFIKNEDKMR 4810 4820 4830 4840 4850 4860 KKTKKNDCLK LLYICNLCTI KYDYVLKIIT YKENNKCWNE FYTDNYYKNN FYELVYFIIK 4870 4880 4890 4900 4910 4920 IIYKNIYINN FFNIFCSIMD NIFKEHKTLN MKLLSLFLFS NKYFKYEEFY HFFNNKMKKD 4930 4940 4950 4960 4970 4980 DRVFKKTFHM KNVCFMPRYS KKSIMYYIFS LFCNKIYNIN KKKKCIHNKR SYIHNKQSYI 4990 5000 5010 5020 5030 5040 HNKRTDVMYD NNVYFHLYEL ARKKLYDYSE KSQKPFDEII NMCLYLLYLY YLCNVLYKCV 5050 5060 5070 5080 5090 5100 RINNVLKGDK DKGDILCDNK KMKYYKKRKN IKLFLNIINS NEYINVNKIF HGKCIYELPF 5110 5120 5130 5140 5150 5160 YVNKERIKKK RNSVREFINN NDNNQENNAD KKKDHHIYNQ NYNHNSYLCD IGKVDESLHS 5170 5180 5190 5200 5210 5220 KEDNKKDVII TNNASIDSTS PSINMNKSVV SSIYSYNSNK EKKKNMRKCI KGLHHTIKNK 5230 5240 5250 5260 5270 5280 LNLYVKLMLD KYIQESSNYI KNENKDIKKT IESKNKDDKI CLLCNFSNYI YKGRLIPFYD 5290 5300 5310 5320 5330 5340 IYIHSECLKW SLNCTQCCYE ENKNKTIVNN DNGTKVDVNL DNADDIINNN NMNMLDNNMN 5350 5360 5370 5380 5390 5400 GPIKNNEENN NNNDNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 5410 5420 5430 5440 5450 5460 KSKKNTQKKK DHVNDVKINQ NNSNNKNNKK KKTSKDNEEL KSDNTKNNKT KDSDGNNNDK 5470 5480 5490 5500 5510 5520 TKLEKINLIH NKQSNEISCK IDNNNIINDI STNNPYMKEK KCKNKEKNRG SKNNNIKNIK 5530 5540 5550 5560 5570 5580 LIDMCEWKED RNFYNIYENM IEVDEDNVKE IIFDSIKSTC FLCGYNNASV YCSNEDCNVK 5590 5600 5610 5620 5630 5640 FHLNCAFYST VIKDPSNNPF FRYLKCFNLV EFNKDTIFYK NMYHDPNVNN SVSSHVCTDN 5650 5660 5670 5680 5690 5700 RYYKEMIEKN YVDIFPVHII YKIKKIWCNK CWNKKKIYNL FYIQKCFMSP YYYDNIKTEE 5710 5720 5730 5740 5750 5760 SVPNKITPMK KDKSDITNEV KEEKDDDILY DSKVHKEYFT LRNILMDDNL LNNIIRNKKS 5770 5780 5790 5800 5810 5820 CSMEIQENND KMKGDNNIDN EDVRNVLCDG EERVSYNRNK LNDILLKMDM KDILKYFIDF 5830 5840 5850 5860 5870 5880 YFENGSYYIL DNILYSVNHC VKIKYKKKSL YNIQDVLNKE TKIGTMMREL EGLISKYVNR 5890 5900 5910 5920 5930 5940 SNDNNYMDRK YDMLLLKNIK SDINNDNNND INNNDNNNNE NNNENINDNN NNNNNNNNNN 5950 5960 5970 5980 5990 6000 NNNNSNNNNN NNYYYYHNNE GKYNEQGSYQ HIDIQNIIND KSVENLIKGY FILKNFLHIG 6010 6020 6030 6040 6050 6060 NNNITLQNED LLILKKSENS FVHNLYDNDK VYNVHVPYVY TKKMNTSYMN KKENDKKYNK 6070 6080 6090 6100 6110 6120 SVNKNSCKSK NSILDNINFD KNKNKITKKY TAFIIDNNEY TTDCSNEENN TSDDEENENR 6130 6140 6150 6160 6170 6180 KNENDDDNIP EHIKMNNIMN SQQKKENDFK NINLYFQLTN VIKKVSINKL EGNFFNYEEK 6190 6200 6210 6220 6230 6240 GNLLGSNVSK IKMNELLECN VGEENFCDDD QKFSDNKNYA SDDEEKKKKK RKNQTRFYNY 6250 6260 6270 6280 6290 6300 PKRISTTNNN KNVNVLVNSL NNNLINKKEY FLNIIMNENN DLYMKKINEK YFPNYHPKKR 6310 6320 6330 6340 6350 6360 KKKKLDNTSY INHNYNYNYP YNYNLLSNNS KSRILKVGCH NILNIGDILK YDGDKIIYPC 6370 6380 6390 6400 6410 6420 GYLNMRIFYN LPSYYLFQIY KNANIDDINR KTKLLEKIFL QLRATYIFSI TLREQNFFFS 6430 6440 6450 6460 6470 6480 ILLFPLINID YFSESDATNF ILAEGYNINE VYMKFLSLFN SQNYICDDMN NDYSHYNAKY 6490 6500 6510 6520 6530 6540 GNIYKCLETY ILKSVEHNKF IDSHTFFGLT LPCVVYQIKY KLFKYMYKHL SEKIKTYIKK 6550 6560 6570 6580 6590 6600 SKDSVMKKRI KGCTREVVYN DNVLCKYSNL DTTIFKENEK ENEKNIRKTV KYKYNINSAM 6610 6620 6630 6640 6650 6660 SYRYLMNISS NLRLYVKKSS IHGYGLYTCE FINEGEPVIE YIGEYIRNII SDKREKYYDK 6670 6680 6690 6700 6710 6720 IESSCYMFRL NENIIIDATK WGNVSRFINH SCEPNCFCKI VSCDQNLKHI VIFAKRDIAA 6730 6740 6750 HEEITYDYQF GVESEGKKLI CLCGSSTCLG RMN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome sequence of the human malaria parasite Plasmodium falciparum." Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W., Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D., Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S. , Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M., Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A., Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I., Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J., Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G. Nature 419:498-511(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Isolate 3D7.
[2]	"Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13." Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D., Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K., Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T., Christodoulou Z. , Clark L., Clark R., Corton C., Cronin A., Davies R.M., Davis P., Dear P., Dearden F., Doggett J., Feltwell T., Goble A., Goodhead I., Gwilliam R., Hamlin N., Hance Z., Harper D., Hauser H., Hornsby T., Holroyd S., Horrocks P., Humphray S., Jagels K., James K.D., Johnson D., Kerhornou A., Knights A., Konfortov B., Kyes S., Larke N., Lawson D., Lennard N., Line A., Maddison M., Mclean J., Mooney P., Moule S., Murphy L., Oliver K., Ormond D., Price C., Quail M.A., Rabbinowitsch E., Rajandream M.A., Rutter S., Rutherford K.M., Sanders M., Simmonds M., Seeger K., Sharp S., Smith R., Squares R., Squares S., Stevens K., Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R., Sulston J.E., Craig A., Newbold C., Barrell B.G. Nature 419:527-531(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Isolate 3D7.
[3]	"Rapid identification of malaria vaccine candidates based on alpha-helical coiled coil protein motif." Villard V., Agak G.W., Frank G., Jafarshad A., Servis C., Nebie I., Sirima S.B., Felger I., Arevalo-Herrera M., Herrera S., Heitz F., Baecker V., Druilhe P., Kajava A.V., Corradin G. PLoS ONE 2:E645-E645(2007) [PubMed] [Europe PMC] [Abstract] Cited for: SYNTHESIS OF 3412-3441, POSSIBLE CANDIDATE MALARIA EPITOPE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL844505 Genomic DNA. Translation: CAG25109.2.
RefSeq	XP_966279.2. XM_961186.2.
3D structure databases
ProteinModelPortal	C6KTD2.
ModBase	Search...
Protein-protein interaction databases
STRING	5833.PFF1440w-1.
Proteomic databases
PRIDE	C6KTD2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblProtists	PFF1440w:mRNA; PFF1440w:pep; PFF1440w.
GeneID	3885750.
KEGG	pfa:PFF1440w.
Organism-specific databases
EuPathDB	PlasmoDB:PF3D7_0629700.
Phylogenomic databases
eggNOG	COG2940.
ProtClustDB	CLSZ2515347.
Family and domain databases
Gene3D	3.30.40.10. 1 hit.
InterPro	IPR001487. Bromodomain. IPR003616. Post-SET_dom. IPR001214. SET_dom. IPR011011. Znf_FYVE_PHD. IPR001965. Znf_PHD. IPR019787. Znf_PHD-finger. IPR001841. Znf_RING. IPR013083. Znf_RING/FYVE/PHD. [Graphical view]
Pfam	PF00856. SET. 1 hit. [Graphical view]
SMART	SM00297. BROMO. 1 hit. SM00249. PHD. 4 hits. SM00508. PostSET. 1 hit. SM00184. RING. 1 hit. SM00317. SET. 1 hit. [Graphical view]
SUPFAM	SSF47370. Bromodomain. 1 hit. SSF57903. FYVE_PHD_ZnF. 1 hit.
PROSITE	PS00633. BROMODOMAIN_1. False negative. PS50014. BROMODOMAIN_2. 1 hit. PS50868. POST_SET. 1 hit. PS50280. SET. 1 hit. PS01359. ZF_PHD_1. 1 hit. PS50016. ZF_PHD_2. 1 hit. PS00518. ZF_RING_1. False negative. PS50089. ZF_RING_2. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

HKNMT_PLAF7

Accession

Primary (citable) accession number: C6KTD2

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 3, 2009
Last sequence update:	September 1, 2009
Last modified:	April 3, 2013
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)