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Protein
Submitted name:

DNA polymerase 1, putative

Gene

PF3D7_0625300

Organism
Plasmodium falciparum (isolate 3D7)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  • 5'-3' exonuclease activity Source: GO_Central
  • DNA binding Source: GeneDB
  • DNA-directed DNA polymerase activity Source: GeneDB

GO - Biological processi

  • DNA-dependent DNA replication Source: GO_Central
  • DNA replication Source: GeneDB

Keywordsi

Molecular functionNucleotidyltransferaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
DNA polymerase 1, putativeImported (EC:2.7.7.7Imported)
Gene namesi
ORF Names:PF3D7_0625300Imported
OrganismiPlasmodium falciparum (isolate 3D7)Imported
Taxonomic identifieri36329 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Laverania)
Proteomesi
  • UP000001450 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiPlasmoDB:PF3D7_0625300.

Subcellular locationi

GO - Cellular componenti

Structurei

3D structure databases

ProteinModelPortaliC6KT89.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1126 – 1335POLAcInterPro annotationAdd BLAST210

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili621 – 649Sequence analysisAdd BLAST29
Coiled coili978 – 998Sequence analysisAdd BLAST21
Coiled coili1002 – 1022Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

HOGENOMiHOG000281606.
InParanoidiC6KT89.
KOiK02335.
OMAiNNEYGKN.

Family and domain databases

Gene3Di3.30.420.10. 1 hit.
InterProiView protein in InterPro
IPR001098. DNA-dir_DNA_pol_A_palm_dom.
IPR002298. DNA_polymerase_A.
IPR036397. RNaseH_sf.
PfamiView protein in Pfam
PF00476. DNA_pol_A. 1 hit.
PRINTSiPR00868. DNAPOLI.
SMARTiView protein in SMART
SM00482. POLAc. 1 hit.

Sequencei

Sequence statusi: Complete.

C6KT89-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLFDSFFKH ALIRINKRNI IYLNATRYYC NNINYNALIN LLNKKNDINK
60 70 80 90 100
EINALYSLLE RLSNYKYKQY KDKLTLKNNI NDEIKITNAD KINNINIERD
110 120 130 140 150
MNISHLDHHH NNHHHNNNHH NINHNNHHHN NHHNINHHNN HHNNHHNNNH
160 170 180 190 200
FNDYKKLIDN WKNDKIKIFI SWCPEIVEDK YKSKCFSIPT YITFHIVITN
210 220 230 240 250
NDIKLNNLLH NSHEYDDWNF NKIIQTINNQ NNLKDKEKEK ENGQQHSQEY
260 270 280 290 300
IGNCKKGESE IPSYDFKESL LEHINESSQL NHSILSHKTK EQTHHTNNNI
310 320 330 340 350
NGNYNNDEHI EEEGKAKTKQ NKTKNSIIEE KKKKTKKKKD EESHNDIINY
360 370 380 390 400
TIKKKTNTNN SLYNIESILN IPKTYEPNIH YDKCIHKEQN HIFFFSFNIS
410 420 430 440 450
ELIINDQVKT KLNECIQQNF IKQNISNIHM DDLFLYVVYD YKNLIHIFNN
460 470 480 490 500
INLKLININN IFDIYIISSL IQLVQRGEKL QNVYNEYLNV KHKILIPNKI
510 520 530 540 550
NDIQNLSLHN FSYFSKFAPE FSDVISAKFG LYGWGKYQKK KDKKNKKQTE
560 570 580 590 600
NHENNENYEN NEYGKNNEYG KNNEYGKNNE YGKNNEYGKN NEYGKNNEYG
610 620 630 640 650
KNNEYGKNNV HNDDTYMDIS NERKNKKSKE VKNKKKMEKK NKVEKEKQNY
660 670 680 690 700
LSFTPHNINN LQDIKKLVFG NKRNISDITE EDNICYSISR NCCLILLFEY
710 720 730 740 750
FINKLEHNIN ILNLYIKVEQ PLILCISHIE EKGIFLNQNK IEEIQKKSDD
760 770 780 790 800
PLIYKNEIEE LCKCNINLNS SKQVSSLIYK QLLDISISTD HTEENMEDAD
810 820 830 840 850
EHTDHQEEEH VNDDNNECVD QLKAYTQTKE KERKDIYNNN NNENNKNNNE
860 870 880 890 900
NYNSSKNHPL ITNTNNDDTS TLNAQDTSDQ HDNYINEHNN YNKFIKNNPF
910 920 930 940 950
YYNNNNNNNN NNNNNNDNNN NISNRNLMNN LVNINYTSLY NKKKNSHPYD
960 970 980 990 1000
ENNKLFFLNS SHNNYNNNNN NINEMSRNKN LQTNNKSLKI LVDEIEKSNY
1010 1020 1030 1040 1050
IKEKEKEKLK KIIRNIKLYR ESKKLVQNYI ENLPKYIQKN TNKIHCNFNQ
1060 1070 1080 1090 1100
IGASTGRLSC DQPNLQNIHS RFRCAISLKG KEENDTHDNN NNNNNIPQIH
1110 1120 1130 1140 1150
ISTNNVSTNN VPMNIMSSTY PLYTMNKKNL ITFDYKQMEL FVMAYLSFDE
1160 1170 1180 1190 1200
QLLKLLNYSD VFIETAKVLF NTNDVTNELR RMTKTVIYGI LYGQTENGLA
1210 1220 1230 1240 1250
KSLLISDTLA SNLIENFFQF FPNVYRFMQM QKFLVKHMNC VYTLIGRKRI
1260 1270 1280 1290 1300
ILPNIKNKYR ISMNTPIQGC AADIMKFSLL SCFSVLNNNI YNNNKLLKMN
1310 1320 1330 1340 1350
NINPLIIHKN QAFLNPTNLI LQVHDELLLE SEHDATKYII QLLNPILENA
1360 1370 1380 1390 1400
FYNLIYYTNS IDRLKLLYDY MHDNISIKTY IDILQDINNK QYNDVKLYNG
1410 1420 1430 1440
VYNTNVSEES HIYNISNNVD HIFQKFNFKL PIKVESGGVY KESS
Length:1,444
Mass (Da):171,130
Last modified:September 1, 2009 - v1
Checksum:iCC458B6616C1D4F6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL844505 Genomic DNA. Translation: CAG25066.1.
RefSeqiXP_966236.1. XM_961143.1.

Genome annotation databases

EnsemblProtistsiCAG25066; CAG25066; PF3D7_0625300.
GeneDBiPF3D7_0625300.1:pep.
GeneIDi3885687.
KEGGipfa:PFF1225c.

Similar proteinsi

Entry informationi

Entry nameiC6KT89_PLAF7
AccessioniPrimary (citable) accession number: C6KT89
Entry historyiIntegrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: December 20, 2017
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported