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Protein
Submitted name:

Cytochrome P450 family 21 subfamily A polypeptide 2

Gene

CYP21A2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. heme binding Source: InterPro
  2. iron ion binding Source: InterPro
  3. oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome P450 family 21 subfamily A polypeptide 2Imported
Gene namesi
Name:CYP21A2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Expressioni

Gene expression databases

BgeeiC6K7H0.
ExpressionAtlasiC6K7H0. baseline.

Family & Domainsi

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR002401. Cyt_P450_E_grp-I.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00463. EP450I.
SUPFAMiSSF48264. SSF48264. 1 hit.

Sequencei

Sequence statusi: Fragment.

C6K7H0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLLLGLLLLL PLLAGARLLW NWWKLRSLHL PPLAPGFLHL LQPDLPIYLL
60 70 80 90 100
GLTQKFGPIY RLHLGLQDVV VLNSKRTIEE AMVKKWADFA GRPEPLTYKL
110
VSRNYPDLSL GDYS
Length:114
Mass (Da):13,026
Last modified:September 1, 2009 - v1
Checksum:i667CC4760E34F458
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei114 – 1141Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GQ166779 Genomic DNA. Translation: ACS94060.1.
GQ166784 Genomic DNA. Translation: ACS94062.1.
GQ166785 Genomic DNA. Translation: ACS94063.1.
GQ166786 Genomic DNA. Translation: ACS94064.1.
GQ166787 Genomic DNA. Translation: ACS94065.1.
GQ166788 Genomic DNA. Translation: ACS94066.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GQ166779 Genomic DNA. Translation: ACS94060.1.
GQ166784 Genomic DNA. Translation: ACS94062.1.
GQ166785 Genomic DNA. Translation: ACS94063.1.
GQ166786 Genomic DNA. Translation: ACS94064.1.
GQ166787 Genomic DNA. Translation: ACS94065.1.
GQ166788 Genomic DNA. Translation: ACS94066.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

NextBioi35483324.

Gene expression databases

BgeeiC6K7H0.
ExpressionAtlasiC6K7H0. baseline.

Family and domain databases

Gene3Di1.10.630.10. 1 hit.
InterProiIPR001128. Cyt_P450.
IPR002401. Cyt_P450_E_grp-I.
[Graphical view]
PfamiPF00067. p450. 1 hit.
[Graphical view]
PRINTSiPR00463. EP450I.
SUPFAMiSSF48264. SSF48264. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The frequency of 21 hydroxylase gene defects, phenotypic effects and other molecular mechanisms in congenital adrenal hyperplasia patients in Turkish population."
    Guney A.I., Kirac D., Bereket A., Guran T., Akcay T., Ulucan K., Ergec D., Koc G., Eren F.
    Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiC6K7H0_HUMAN
AccessioniPrimary (citable) accession number: C6K7H0
Entry historyi
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: October 29, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.