C6I3B3 (C6I3B3_9BACE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphopantetheine adenylyltransferase HAMAP MF_00151
EC=2.7.7.3 HAMAP MF_00151

Alternative name(s):
Dephospho-CoA pyrophosphorylase HAMAP MF_00151
Pantetheine-phosphate adenylyltransferase HAMAP MF_00151

Gene names

Name:	coaD HAMAP MF_00151
ORF Names:	BSHG_01621 EMBL EES88702.1

Organism

Bacteroides sp. 3_2_5 EMBL EES88702.1

Taxonomic identifier

457392 [NCBI]

Taxonomic lineage

Bacteria › Bacteroidetes › Bacteroidia › Bacteroidales › Bacteroidaceae › Bacteroides

Protein attributes

Sequence length	150 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate By similarity. HAMAP MF_00151
Catalytic activity	ATP + pantetheine 4'-phosphate = diphosphate + 3'-dephospho-CoA. HAMAP MF_00151
Pathway	Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5. HAMAP MF_00151
Subunit structure	Homohexamer By similarity. HAMAP MF_00151
Subcellular location	Cytoplasm By similarity HAMAP MF_00151.
Sequence similarities	Belongs to the bacterial CoaD family. HAMAP MF_00151

Ontologies

Keywords
Biological process	Coenzyme A biosynthesis HAMAP MF_00151
Cellular component	Cytoplasm HAMAP MF_00151
Ligand	ATP-binding HAMAP MF_00151 Nucleotide-binding
Molecular function	Nucleotidyltransferase HAMAP MF_00151 EMBL EES88702.1 Transferase
Gene Ontology (GO)
Biological process	coenzyme A biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW pantetheine-phosphate adenylyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C6I3B3 [UniParc]. Last modified September 1, 2009. Version 1. Checksum: 2112112BED537838	FASTA	150	17,492
	10 20 30 40 50 60 MRRAIFPGTF DPFTIGHYSV VQRTLTFMDE VVIGIGINEN KNTYFPIEKR VEMIRKFYKD 70 80 90 100 110 120 EPRIKVESYD CLTIDFARQV DAQFIVRGIR TVKDFEYEET IADINRKLAG IETILLFTEP 130 140 150 ELTCVSSTIV RELLGYNKDI SMFIPKGMEM

References

[1]

"The Genome Sequence of Bacteroides sp. strain 3_2_5." The Broad Institute Genome Sequencing Platform Ward D., Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C. , Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C., Allen-Vercoe E., Strauss J., Ambrose C., Lander E., Nusbaum C., Galagan J., Birren B. Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: 3_2_5 EMBL EES88702.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	GG693893 Genomic DNA. Translation: EES88702.1.
3D structure databases
ProteinModelPortal	C6I3B3.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
PATRIC	30519172. VBIBacSp21143_1158.
Family and domain databases
HAMAP	MF_00151. PPAT_bact. [Tree]
InterPro	IPR004821. Cyt_trans-rel. IPR004820. Cytidylyltransf. IPR001980. LPS_biosynth. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
Pfam	PF01467. CTP_transf_2. 1 hit. [Graphical view]
PRINTS	PR01020. LPSBIOSNTHSS.
TIGRFAMs	TIGR01510. CoaD_prev_kdtB. 1 hit. TIGR00125. Cyt_tran_rel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C6I3B3_9BACE

Accession

Primary (citable) accession number: C6I3B3

Entry history

Integrated into UniProtKB/TrEMBL:	September 1, 2009
Last sequence update:	September 1, 2009
Last modified:	December 14, 2011
This is version 12 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)