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Protein

dTDP-glucose 4,6-dehydratase

Gene

rmlB

Organism
Streptococcus suis (strain BM407)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O.UniRule annotation

Cofactori

NAD(+)UniRule annotation

GO - Molecular functioni

  1. coenzyme binding Source: InterPro
  2. dTDP-glucose 4,6-dehydratase activity Source: UniProtKB-EC

GO - Biological processi

  1. nucleotide-sugar metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationImported

Enzyme and pathway databases

BioCyciSSUI568814:GJD0-723-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
dTDP-glucose 4,6-dehydrataseUniRule annotation (EC:4.2.1.46UniRule annotation)
Gene namesi
Name:rmlBImported
Ordered Locus Names:SSUBM407_0659Imported
OrganismiStreptococcus suis (strain BM407)Imported
Taxonomic identifieri568814 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000009077: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi568814.SSUBM407_0659.

Structurei

3D structure databases

ProteinModelPortaliC6GXE6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG1088.
HOGENOMiHOG000168006.
KOiK01710.
OMAiHEDWWKA.
OrthoDBiEOG6PZXCX.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR005888. dTDP_Gluc_deHydtase.
IPR001509. Epimerase_deHydtase_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR10366:SF41. PTHR10366:SF41. 1 hit.
PfamiPF01370. Epimerase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01181. dTDP_gluc_dehyt. 1 hit.

Sequencei

Sequence statusi: Complete.

C6GXE6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSQFKNIIVT GGAGFIGSNF VHYVYNNHPD VHVTVLDKLT YAGNKANLEA
60 70 80 90 100
ILGDRVELVV GDIADAELVD KLAAKADAIV HYAAESHNDN SLNDPSPFIH
110 120 130 140 150
TNFIGTYTLL EAARKYDIRF HHVSTDEVYG DLPLREDLPG HGEGPGEKFT
160 170 180 190 200
AETNYNPSSP YSSTKAASDL IVKAWVRSFG VKATISNCSN NYGPYQHIEK
210 220 230 240 250
FIPRQITNIL AGIKPKLYGE GKNVRDWIHT NDHSTGVWAI LTKGRMGETY
260 270 280 290 300
LIGADGEKNN KEVLELILEK MGQPKDAYDH VTDRAGHDLR YAIDASKLRD
310 320 330 340
ELGWTPQFTD FSQGLEETIQ WYTDNQDWWK AEKEAVEANY AKTQEVIK
Length:348
Mass (Da):38,932
Last modified:September 1, 2009 - v1
Checksum:iEEA3464D7CBCF2A1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM252032 Genomic DNA. Translation: CAZ55493.1.
RefSeqiYP_003028418.1. NC_012926.1.

Genome annotation databases

EnsemblBacteriaiCAZ55493; CAZ55493; SSUBM407_0659.
GeneIDi8153488.
KEGGissb:SSUBM407_0659.
PATRICi19782087. VBIStrSui1141_0684.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM252032 Genomic DNA. Translation: CAZ55493.1.
RefSeqiYP_003028418.1. NC_012926.1.

3D structure databases

ProteinModelPortaliC6GXE6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi568814.SSUBM407_0659.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAZ55493; CAZ55493; SSUBM407_0659.
GeneIDi8153488.
KEGGissb:SSUBM407_0659.
PATRICi19782087. VBIStrSui1141_0684.

Phylogenomic databases

eggNOGiCOG1088.
HOGENOMiHOG000168006.
KOiK01710.
OMAiHEDWWKA.
OrthoDBiEOG6PZXCX.

Enzyme and pathway databases

BioCyciSSUI568814:GJD0-723-MONOMER.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR005888. dTDP_Gluc_deHydtase.
IPR001509. Epimerase_deHydtase_N.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR10366:SF41. PTHR10366:SF41. 1 hit.
PfamiPF01370. Epimerase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR01181. dTDP_gluc_dehyt. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BM407Imported.

Entry informationi

Entry nameiC6GXE6_STRS4
AccessioniPrimary (citable) accession number: C6GXE6
Entry historyi
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: January 7, 2015
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.