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C6GWP2

- C6GWP2_STRS4

UniProt

C6GWP2 - C6GWP2_STRS4

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Protein

Alanine racemase

Gene

alr

Organism
Streptococcus suis (strain BM407)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

Note: Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei40 – 401Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei136 – 1361SubstrateUniRule annotation
Active sitei263 – 2631Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei310 – 3101Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciSSUI568814:GJD0-1766-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Name:alrImported
Ordered Locus Names:SSUBM407_1686Imported
OrganismiStreptococcus suis (strain BM407)Imported
Taxonomic identifieri568814 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000009077: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei40 – 401N6-(pyridoxal phosphate)lysineUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi568814.SSUBM407_1686.

Structurei

3D structure databases

ProteinModelPortaliC6GWP2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0787.
HOGENOMiHOG000031444.
KOiK01775.
OMAiIYSHLAL.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C6GWP2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MIESEHRPTQ IRVNLDAIAE NFEQVMTNLP PKTEAFAVVK ANAYGHGAVA
60 70 80 90 100
VAKKLSSQAA GFCVSNLDEA LELRKAGIEH PILILGVVPV RFLPVAHQLN
110 120 130 140 150
ISVTVASLDW LQDAKDLEAD LSGLTVHLKL DTGMGRIGFR KIADLLQAIA
160 170 180 190 200
ILEELEYDIE GVYTHFATAD EVEQAHFESQ LSVFKEFLDV LPITPRWIHA
210 220 230 240 250
SNSATSIWHA DTVFNLVRLG NILYGLNPSG RVLELPFGVQ PALSLVSEIV
260 270 280 290 300
HVKQVEAGTT IGYGATYHST DSEWIATVPI GYADGLVRSL QGLSVLVDGQ
310 320 330 340 350
ACEIVGRISM DQITIRLPRA YPLGQKVTLI GQDGDKTISV QEWADRIGTI
360
NYEVVCLLTD RLPRIFE
Length:367
Mass (Da):40,211
Last modified:September 1, 2009 - v1
Checksum:i5701743FE1F9D672
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM252032 Genomic DNA. Translation: CAZ56542.1.
RefSeqiYP_003029382.1. NC_012926.1.

Genome annotation databases

EnsemblBacteriaiCAZ56542; CAZ56542; SSUBM407_1686.
GeneIDi8155115.
KEGGissb:SSUBM407_1686.
PATRICi19784171. VBIStrSui1141_1721.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FM252032 Genomic DNA. Translation: CAZ56542.1 .
RefSeqi YP_003029382.1. NC_012926.1.

3D structure databases

ProteinModelPortali C6GWP2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 568814.SSUBM407_1686.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAZ56542 ; CAZ56542 ; SSUBM407_1686 .
GeneIDi 8155115.
KEGGi ssb:SSUBM407_1686.
PATRICi 19784171. VBIStrSui1141_1721.

Phylogenomic databases

eggNOGi COG0787.
HOGENOMi HOG000031444.
KOi K01775.
OMAi IYSHLAL.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci SSUI568814:GJD0-1766-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BM407Imported.

Entry informationi

Entry nameiC6GWP2_STRS4
AccessioniPrimary (citable) accession number: C6GWP2
Entry historyi
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: November 26, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3