C6G7W3 (C6G7W3_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Pyrimidinergic receptor P2Y4 EMBL ACS66695.1

Gene names

Name:

P2RY4 EMBL ACS66695.1

Organism

Homo sapiens (Human) EMBL ACS66695.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	121 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the G-protein coupled receptor 1 family. RuleBase RU000688

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS002286
Molecular function	G-protein coupled receptor RuleBase RU000688 SAAS SAAS002286 Receptor Transducer
Gene Ontology (GO)
Biological_process	transepithelial chloride transport Inferred from electronic annotation. Source: Compara
Cellular_component	apical plasma membrane Inferred from electronic annotation. Source: Compara basolateral plasma membrane Inferred from electronic annotation. Source: Compara integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: Compara G-protein coupled purinergic nucleotide receptor activity Inferred from electronic annotation. Source: InterPro UTP-activated nucleotide receptor activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL ACS66695.1
	Non-terminal residue	121	1	EMBL ACS66695.1

Sequences

	Sequence		Length	Mass (Da)
	C6G7W3 [UniParc]. Last modified September 1, 2009. Version 1. Checksum: C68E644A8759C0A5	FASTA	121	14,001
	10 20 30 40 50 60 VLSLPTLIYY YAAHNHWPFG TEICKFVRFL FYWNLYCSVL FLTCISVHRY LGICHPLRAL 70 80 90 100 110 120 RWGRPRLAGL LCLAVWLVVA GCLVPNLFFV TTSNKGTTVL CHDTTRPEEF DHYVHFSSAV M

References

[1]	"Role of PKC and Src in the activation of MAP kinases by ATP in MCF-7 cells." Scodelaro Bilbao P.G., Boland R.L., Santillan G.E. Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	"ATP modulates transcription factors through P2Y2 and P2Y4 receptors via PKC/MAPKs and PKC/Src pathways in MCF-7 cells." Scodelaro Bilbao P., Boland R., Santillan G. Arch. Biochem. Biophys. 494:7-14(2010) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FJ599701 mRNA. Translation: ACS66695.1.
IPI	IPI00019403.
3D structure databases
ModBase	Search...
Protein family/group databases
GPCRDB	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Gene expression databases
ArrayExpress	C6G7W3.
Bgee	C6G7W3.
Family and domain databases
InterPro	IPR000276. GPCR_Rhodpsn. IPR017452. GPCR_Rhodpsn_7TM. IPR000018. P2Y4_purnocptor. IPR002286. purinergic_P2Y_rcpt. [Graphical view]
Pfam	PF00001. 7tm_1. 1 hit. [Graphical view]
PRINTS	PR01066. P2Y4PRNOCPTR. PR01157. P2YPURNOCPTR.
PROSITE	PS00237. G_PROTEIN_RECEP_F1_1. 1 hit. PS50262. G_PROTEIN_RECEP_F1_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
BindingDB	C6G7W3.
NextBio	35483014.

Entry information

Entry name

C6G7W3_HUMAN

Accession

Primary (citable) accession number: C6G7W3

Entry history

Integrated into UniProtKB/TrEMBL:	September 1, 2009
Last sequence update:	September 1, 2009
Last modified:	May 29, 2013
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.