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C6EJL2

- C6EJL2_ECOBD

UniProt

C6EJL2 - C6EJL2_ECOBD

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Protein
Submitted name:

2-oxoglutarate dehydrogenase, E1 subunit

Gene
sucA, B21_00674, ECBD_2935, ECD_00685
Organism
Escherichia coli (strain B / BL21-DE3)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. oxoglutarate dehydrogenase (succinyl-transferring) activity Source: UniProtKB-EC
  2. thiamine pyrophosphate binding Source: InterPro

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
2-oxoglutarate dehydrogenase, E1 subunitImported (EC:1.2.4.2Imported)
Submitted name:
Alpha-ketoglutarate decarboxylaseImported (EC:1.2.4.2Imported)
Submitted name:
E1(0) component of 2-oxoglutarate dehydrogenase, subunit of 2-oxoglutarate decarboxylase, thiamin-requiring and 2-oxoglutarate dehydrogenase complexImported (EC:1.2.4.2Imported)
Gene namesi
Name:sucAImported
Ordered Locus Names:B21_00674Imported, ECBD_2935Imported, ECD_00685Imported
OrganismiEscherichia coli (strain B / BL21-DE3)
Taxonomic identifieri469008 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000001509: Chromosome, UP000009074: Chromosome, UP000002032: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi469008.ECBD_2935.

Structurei

3D structure databases

ProteinModelPortaliC6EJL2.
SMRiC6EJL2. Positions 85-933.

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0567.
HOGENOMiHOG000259587.
KOiK00164.
OMAiGHQNANL.

Family and domain databases

Gene3Di3.40.50.970. 2 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.

Sequencei

Sequence statusi: Complete.

C6EJL2-1 [UniParc]FASTAAdd to Basket

« Hide

MQNSALKAWL DSSYLSGANQ SWIEQLYEDF LTDPDSVDAN WRSTFQQLPG    50
TGVKPDQFHS QTREYFRRLA KDASRYSSTI SDPDTNVKQV KVLQLINAYR 100
FRGHQHANLD PLGLWQQDKV ADLDPSFHDL TEADFQETFN VGSFASGKET 150
MKLGELLEAL KQTYCGPIGA EYMHITSTEE KRWIQQRIES GRATFNSEEK 200
KRFLSELTAA EGLERYLGAK FPGAKRFSLE GGDALIPMLK EMIRHAGNSG 250
TREVVLGMAH RGRLNVLVNV LGKKPQDLFD EFAGKHKEHL GTGDVKYHMG 300
FSSDFQTDGG LVHLALAFNP SHLEIVSPVV IGSVRARLDR LDEPSSNKVL 350
PITIHGDAAV TGQGVVQETL NMSKARGYEV GGTVRIVINN QVGFTTSNPL 400
DARSTPYCTD IGKMVQAPIF HVNADDPEAV AFVTRLALDF RNTFKRDVFI 450
DLVCYRRHGH NEADEPSATQ PLMYQKIKKH PTPRKIYADK LEQEKVATLE 500
DATEMVNLYR DALDAGDCVV AEWRPMNMHS FTWSPYLNHE WDEEYPNKVE 550
MKRLQELAKR ISTVPEAVEM QSRVAKIYGD RQAMAAGEKL FDWGGAENLA 600
YATLVDEGIP VRLSGEDSGR GTFFHRHAVI HNQSNGSTYT PLQHIHNGQG 650
AFRVWDSVLS EEAVLAFEYG YATAEPRTLT IWEAQFGDFA NGAQVVIDQF 700
ISSGEQKWGR MCGLVMLLPH GYEGQGPEHS SARLERYLQL CAEQNMQVCV 750
PSTPAQVYHM LRRQALRGMR RPLVVMSPKS LLRHPLAVSS LEELANGTFL 800
PAIGEIDELD PKGVKRVVMC SGKVYYDLLE QRRKNNQHDV AIVRIEQLYP 850
FPHKAMQEVL QQFAHVKDFV WCQEEPLNQG AWYCSQHHFR EVIPFGASLR 900
YAGRPASASP AVGYMSVHQK QQQDLVNDAL NVE 933
Length:933
Mass (Da):105,062
Last modified:September 1, 2009 - v1
Checksum:iEAEF8429EC31E749
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001665 Genomic DNA. Translation: ACT29950.1.
CP001509 Genomic DNA. Translation: ACT42560.1.
AM946981 Genomic DNA. Translation: CAQ31191.1.
RefSeqiYP_002998518.1. NC_012892.2.
YP_003037135.1. NC_012947.1.
YP_003053331.1. NC_012971.2.

Genome annotation databases

EnsemblBacteriaiACT29950; ACT29950; ECBD_2935.
ACT42560; ACT42560; ECD_00685.
CAQ31191; CAQ31191; B21_00674.
GeneIDi8116723.
8156919.
8183595.
KEGGiebd:ECBD_2935.
ebe:B21_00674.
ebl:ECD_00685.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001665 Genomic DNA. Translation: ACT29950.1 .
CP001509 Genomic DNA. Translation: ACT42560.1 .
AM946981 Genomic DNA. Translation: CAQ31191.1 .
RefSeqi YP_002998518.1. NC_012892.2.
YP_003037135.1. NC_012947.1.
YP_003053331.1. NC_012971.2.

3D structure databases

ProteinModelPortali C6EJL2.
SMRi C6EJL2. Positions 85-933.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 469008.ECBD_2935.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACT29950 ; ACT29950 ; ECBD_2935 .
ACT42560 ; ACT42560 ; ECD_00685 .
CAQ31191 ; CAQ31191 ; B21_00674 .
GeneIDi 8116723.
8156919.
8183595.
KEGGi ebd:ECBD_2935.
ebe:B21_00674.
ebl:ECD_00685.

Phylogenomic databases

eggNOGi COG0567.
HOGENOMi HOG000259587.
KOi K00164.
OMAi GHQNANL.

Family and domain databases

Gene3Di 3.40.50.970. 2 hits.
InterProi IPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view ]
PANTHERi PTHR23152. PTHR23152. 1 hit.
Pfami PF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view ]
PIRSFi PIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTi SM00861. Transket_pyr. 1 hit.
[Graphical view ]
SUPFAMi SSF52518. SSF52518. 2 hits.
TIGRFAMsi TIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Sequencing and gene expression analysis of Escherichia coli BL21(DE3)."
    Krempl P.M., Mairhofer J., Eisenkolb M., Specht T., Leparc G.G., Kreil D.P., Bayer K., Striedner G.
    Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BL21Imported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: B / BL21-DE3 [Korea] and BL21Imported.
  3. "Sequencing and gene expression analysis of Escherichia coli BL21."
    Leparc G., Striedner G., Bayer K., Kreil D., Krempl P.M.
    Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: B / BL21-DE3 [Austria].
  4. "Complete sequence of Escherichia coli 'BL21-Gold(DE3)pLysS AG'."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., LaButti K.M., Clum A., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I., Sorek R., Rubin E.
    Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BL21-GoldImported.
  5. "Complete sequence of Escherichia coli BL21(DE3)."
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., LaButti K.M., Clum A., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I., Sorek R., Rubin E.
    Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: B / BL21-DE3 [JGI].
  6. Jeong H., Shim J.-H., Studier F.W., Oh T.K., Kim J.F.
    Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BL21.

Entry informationi

Entry nameiC6EJL2_ECOBD
AccessioniPrimary (citable) accession number: C6EJL2
Secondary accession number(s): C5W1A1
Entry historyi
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: September 3, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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