Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

C6EJL2

- C6EJL2_ECOBD

UniProt

C6EJL2 - C6EJL2_ECOBD

Protein
Submitted name:

2-oxoglutarate dehydrogenase, E1 subunit

Gene

sucA

Organism
Escherichia coli (strain B / BL21-DE3)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 40 (01 Oct 2014)
      Sequence version 1 (01 Sep 2009)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    GO - Molecular functioni

    1. oxoglutarate dehydrogenase (succinyl-transferring) activity Source: UniProtKB-EC
    2. thiamine pyrophosphate binding Source: InterPro

    GO - Biological processi

    1. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    OxidoreductaseImported

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    2-oxoglutarate dehydrogenase, E1 subunitImported (EC:1.2.4.2Imported)
    Submitted name:
    Alpha-ketoglutarate decarboxylaseImported (EC:1.2.4.2Imported)
    Submitted name:
    E1(0) component of 2-oxoglutarate dehydrogenase, subunit of 2-oxoglutarate decarboxylase, thiamin-requiring and 2-oxoglutarate dehydrogenase complexImported (EC:1.2.4.2Imported)
    Gene namesi
    Name:sucAImported
    Ordered Locus Names:B21_00674Imported, ECBD_2935Imported, ECD_00685Imported
    OrganismiEscherichia coli (strain B / BL21-DE3)Imported
    Taxonomic identifieri469008 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000002032: Chromosome, UP000001509: Chromosome, UP000009074: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi469008.ECBD_2935.

    Structurei

    3D structure databases

    ProteinModelPortaliC6EJL2.
    SMRiC6EJL2. Positions 85-933.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiCOG0567.
    HOGENOMiHOG000259587.
    KOiK00164.
    OMAiGHQNANL.

    Family and domain databases

    Gene3Di3.40.50.970. 2 hits.
    InterProiIPR011603. 2oxoglutarate_DH_E1.
    IPR001017. DH_E1.
    IPR029061. THDP-binding.
    IPR005475. Transketolase-like_Pyr-bd.
    [Graphical view]
    PANTHERiPTHR23152. PTHR23152. 1 hit.
    PfamiPF00676. E1_dh. 1 hit.
    PF02779. Transket_pyr. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
    SMARTiSM00861. Transket_pyr. 1 hit.
    [Graphical view]
    SUPFAMiSSF52518. SSF52518. 2 hits.
    TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    C6EJL2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQNSALKAWL DSSYLSGANQ SWIEQLYEDF LTDPDSVDAN WRSTFQQLPG    50
    TGVKPDQFHS QTREYFRRLA KDASRYSSTI SDPDTNVKQV KVLQLINAYR 100
    FRGHQHANLD PLGLWQQDKV ADLDPSFHDL TEADFQETFN VGSFASGKET 150
    MKLGELLEAL KQTYCGPIGA EYMHITSTEE KRWIQQRIES GRATFNSEEK 200
    KRFLSELTAA EGLERYLGAK FPGAKRFSLE GGDALIPMLK EMIRHAGNSG 250
    TREVVLGMAH RGRLNVLVNV LGKKPQDLFD EFAGKHKEHL GTGDVKYHMG 300
    FSSDFQTDGG LVHLALAFNP SHLEIVSPVV IGSVRARLDR LDEPSSNKVL 350
    PITIHGDAAV TGQGVVQETL NMSKARGYEV GGTVRIVINN QVGFTTSNPL 400
    DARSTPYCTD IGKMVQAPIF HVNADDPEAV AFVTRLALDF RNTFKRDVFI 450
    DLVCYRRHGH NEADEPSATQ PLMYQKIKKH PTPRKIYADK LEQEKVATLE 500
    DATEMVNLYR DALDAGDCVV AEWRPMNMHS FTWSPYLNHE WDEEYPNKVE 550
    MKRLQELAKR ISTVPEAVEM QSRVAKIYGD RQAMAAGEKL FDWGGAENLA 600
    YATLVDEGIP VRLSGEDSGR GTFFHRHAVI HNQSNGSTYT PLQHIHNGQG 650
    AFRVWDSVLS EEAVLAFEYG YATAEPRTLT IWEAQFGDFA NGAQVVIDQF 700
    ISSGEQKWGR MCGLVMLLPH GYEGQGPEHS SARLERYLQL CAEQNMQVCV 750
    PSTPAQVYHM LRRQALRGMR RPLVVMSPKS LLRHPLAVSS LEELANGTFL 800
    PAIGEIDELD PKGVKRVVMC SGKVYYDLLE QRRKNNQHDV AIVRIEQLYP 850
    FPHKAMQEVL QQFAHVKDFV WCQEEPLNQG AWYCSQHHFR EVIPFGASLR 900
    YAGRPASASP AVGYMSVHQK QQQDLVNDAL NVE 933
    Length:933
    Mass (Da):105,062
    Last modified:September 1, 2009 - v1
    Checksum:iEAEF8429EC31E749
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001665 Genomic DNA. Translation: ACT29950.1.
    CP001509 Genomic DNA. Translation: ACT42560.1.
    AM946981 Genomic DNA. Translation: CAQ31191.1.
    RefSeqiYP_002998518.1. NC_012892.2.
    YP_003037135.1. NC_012947.1.
    YP_003053331.1. NC_012971.2.

    Genome annotation databases

    EnsemblBacteriaiACT29950; ACT29950; ECBD_2935.
    ACT42560; ACT42560; ECD_00685.
    CAQ31191; CAQ31191; B21_00674.
    GeneIDi8116723.
    8156919.
    8183595.
    KEGGiebd:ECBD_2935.
    ebe:B21_00674.
    ebl:ECD_00685.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001665 Genomic DNA. Translation: ACT29950.1 .
    CP001509 Genomic DNA. Translation: ACT42560.1 .
    AM946981 Genomic DNA. Translation: CAQ31191.1 .
    RefSeqi YP_002998518.1. NC_012892.2.
    YP_003037135.1. NC_012947.1.
    YP_003053331.1. NC_012971.2.

    3D structure databases

    ProteinModelPortali C6EJL2.
    SMRi C6EJL2. Positions 85-933.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 469008.ECBD_2935.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACT29950 ; ACT29950 ; ECBD_2935 .
    ACT42560 ; ACT42560 ; ECD_00685 .
    CAQ31191 ; CAQ31191 ; B21_00674 .
    GeneIDi 8116723.
    8156919.
    8183595.
    KEGGi ebd:ECBD_2935.
    ebe:B21_00674.
    ebl:ECD_00685.

    Phylogenomic databases

    eggNOGi COG0567.
    HOGENOMi HOG000259587.
    KOi K00164.
    OMAi GHQNANL.

    Family and domain databases

    Gene3Di 3.40.50.970. 2 hits.
    InterProi IPR011603. 2oxoglutarate_DH_E1.
    IPR001017. DH_E1.
    IPR029061. THDP-binding.
    IPR005475. Transketolase-like_Pyr-bd.
    [Graphical view ]
    PANTHERi PTHR23152. PTHR23152. 1 hit.
    Pfami PF00676. E1_dh. 1 hit.
    PF02779. Transket_pyr. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000157. Oxoglu_dh_E1. 1 hit.
    SMARTi SM00861. Transket_pyr. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52518. SSF52518. 2 hits.
    TIGRFAMsi TIGR00239. 2oxo_dh_E1. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Sequencing and gene expression analysis of Escherichia coli BL21(DE3)."
      Krempl P.M., Mairhofer J., Eisenkolb M., Specht T., Leparc G.G., Kreil D.P., Bayer K., Striedner G.
      Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BL21Imported.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: B / BL21-DE3 [Austria]Imported, B / BL21-DE3 [JGI]Imported, B / BL21-DE3 [Korea]Imported and BL21Imported.
    3. "Sequencing and gene expression analysis of Escherichia coli BL21."
      Leparc G., Striedner G., Bayer K., Kreil D., Krempl P.M.
      Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    4. "Complete sequence of Escherichia coli 'BL21-Gold(DE3)pLysS AG'."
      US DOE Joint Genome Institute
      Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., LaButti K.M., Clum A., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I., Sorek R., Rubin E.
      Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BL21-GoldImported.
    5. "Complete sequence of Escherichia coli BL21(DE3)."
      Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., LaButti K.M., Clum A., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I., Sorek R., Rubin E.
      Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    6. Jeong H., Shim J.-H., Studier F.W., Oh T.K., Kim J.F.
      Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BL21.

    Entry informationi

    Entry nameiC6EJL2_ECOBD
    AccessioniPrimary (citable) accession number: C6EJL2
    Secondary accession number(s): C5W1A1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 1, 2009
    Last sequence update: September 1, 2009
    Last modified: October 1, 2014
    This is version 40 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3