Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

C6EEB3

- C6EEB3_ECOBD

UniProt

C6EEB3 - C6EEB3_ECOBD

Protein

Xylose isomerase

Gene

xylA

Organism
Escherichia coli (strain B / BL21-DE3)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 40 (01 Oct 2014)
      Sequence version 1 (01 Sep 2009)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

    Cofactori

    Binds 2 magnesium ions per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei101 – 1011UniRule annotation
    Active sitei104 – 1041UniRule annotation
    Metal bindingi232 – 2321Magnesium 1UniRule annotation
    Metal bindingi268 – 2681Magnesium 1UniRule annotation
    Metal bindingi268 – 2681Magnesium 2UniRule annotation
    Metal bindingi271 – 2711Magnesium 2UniRule annotation
    Metal bindingi296 – 2961Magnesium 1UniRule annotation
    Metal bindingi307 – 3071Magnesium 2UniRule annotation
    Metal bindingi309 – 3091Magnesium 2UniRule annotation
    Metal bindingi339 – 3391Magnesium 1UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. xylose isomerase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-xylose metabolic process Source: UniProtKB-HAMAP
    2. pentose-phosphate shunt Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Biological processi

    Carbohydrate metabolism, Pentose shuntUniRule annotationSAAS annotation, Xylose metabolismUniRule annotationSAAS annotation

    Keywords - Ligandi

    MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Xylose isomeraseUniRule annotation (EC:5.3.1.5UniRule annotation)
    Gene namesi
    Name:xylAUniRule annotationImported
    Ordered Locus Names:B21_03368Imported, ECBD_0169Imported, ECD_03417Imported
    OrganismiEscherichia coli (strain B / BL21-DE3)Imported
    Taxonomic identifieri469008 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000002032: Chromosome, UP000001509: Chromosome, UP000009074: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotationSAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotationSAAS annotation

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotationSAAS annotation

    Protein-protein interaction databases

    STRINGi469008.ECBD_0169.

    Structurei

    3D structure databases

    ProteinModelPortaliC6EEB3.
    SMRiC6EEB3. Positions 2-439.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the xylose isomerase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2115.
    HOGENOMiHOG000252293.
    KOiK01805.
    OMAiLFHAHIG.

    Family and domain databases

    Gene3Di3.20.20.150. 1 hit.
    HAMAPiMF_00455. Xylose_isom_A.
    InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
    IPR013452. Xylose_isom_bac.
    IPR001998. Xylose_isomerase.
    [Graphical view]
    PfamiPF01261. AP_endonuc_2. 1 hit.
    [Graphical view]
    PRINTSiPR00688. XYLOSISMRASE.
    SUPFAMiSSF51658. SSF51658. 1 hit.
    TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
    PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C6EEB3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQAYFDQLDR VRYEGSKSSN PLAFRHYNPD ELVLGKRMEE HLRFAACYWH    50
    TFCWNGADMF GVGAFNRPWQ QPGEALALAK RKADVAFEFF HKLHVPFYCF 100
    HDVDVSPEGA SLKEYINNFA QMVDVLAGKQ EESGVKLLWG TANCFTNPRY 150
    GAGAATNPDP EVFSWAATQV VTAMEATHKL GGENYVLWGG REGYETLLNT 200
    DLRQEREQLG RFMQMVVEHK HKIGFQGTLL IEPKPQEPTK HQYDYDAATV 250
    YGFLKQFGLE KEIKLNIEAN HATLAGHSFH HEIATAIALG LFGSVDANRG 300
    DAQLGWDTDQ FPNSVEENAL VMYEILKAGG FTTGGLNFDA KVRRQSTDKY 350
    DLFYGHIGAM DTMALALKIA ARMIEDGELD KRIAQRYSGW NSELGQQILK 400
    GQMSLADLAK YAQEHNLSPV HQSGRQEQLE NLVNHYLFDK 440
    Length:440
    Mass (Da):49,719
    Last modified:September 1, 2009 - v1
    Checksum:i6E21039B6EC0561F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001665 Genomic DNA. Translation: ACT27245.1.
    CP001509 Genomic DNA. Translation: ACT45217.1.
    AM946981 Genomic DNA. Translation: CAQ33885.1.
    RefSeqiYP_003001115.1. NC_012892.2.
    YP_003034430.1. NC_012947.1.
    YP_003055988.1. NC_012971.2.

    Genome annotation databases

    EnsemblBacteriaiACT27245; ACT27245; ECBD_0169.
    ACT45217; ACT45217; ECD_03417.
    CAQ33885; CAQ33885; B21_03368.
    GeneIDi8114364.
    8157021.
    8180956.
    KEGGiebd:ECBD_0169.
    ebe:B21_03368.
    ebl:ECD_03417.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001665 Genomic DNA. Translation: ACT27245.1 .
    CP001509 Genomic DNA. Translation: ACT45217.1 .
    AM946981 Genomic DNA. Translation: CAQ33885.1 .
    RefSeqi YP_003001115.1. NC_012892.2.
    YP_003034430.1. NC_012947.1.
    YP_003055988.1. NC_012971.2.

    3D structure databases

    ProteinModelPortali C6EEB3.
    SMRi C6EEB3. Positions 2-439.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 469008.ECBD_0169.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACT27245 ; ACT27245 ; ECBD_0169 .
    ACT45217 ; ACT45217 ; ECD_03417 .
    CAQ33885 ; CAQ33885 ; B21_03368 .
    GeneIDi 8114364.
    8157021.
    8180956.
    KEGGi ebd:ECBD_0169.
    ebe:B21_03368.
    ebl:ECD_03417.

    Phylogenomic databases

    eggNOGi COG2115.
    HOGENOMi HOG000252293.
    KOi K01805.
    OMAi LFHAHIG.

    Family and domain databases

    Gene3Di 3.20.20.150. 1 hit.
    HAMAPi MF_00455. Xylose_isom_A.
    InterProi IPR013022. Xyl_isomerase-like_TIM-brl.
    IPR013452. Xylose_isom_bac.
    IPR001998. Xylose_isomerase.
    [Graphical view ]
    Pfami PF01261. AP_endonuc_2. 1 hit.
    [Graphical view ]
    PRINTSi PR00688. XYLOSISMRASE.
    SUPFAMi SSF51658. SSF51658. 1 hit.
    TIGRFAMsi TIGR02630. xylose_isom_A. 1 hit.
    PROSITEi PS51415. XYLOSE_ISOMERASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequencing and gene expression analysis of Escherichia coli BL21(DE3)."
      Krempl P.M., Mairhofer J., Eisenkolb M., Specht T., Leparc G.G., Kreil D.P., Bayer K., Striedner G.
      Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BL21Imported.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: B / BL21-DE3 [Austria]Imported, B / BL21-DE3 [JGI]Imported, B / BL21-DE3 [Korea]Imported and BL21Imported.
    3. "Sequencing and gene expression analysis of Escherichia coli BL21."
      Leparc G., Striedner G., Bayer K., Kreil D., Krempl P.M.
      Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    4. "Complete sequence of Escherichia coli 'BL21-Gold(DE3)pLysS AG'."
      US DOE Joint Genome Institute
      Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., LaButti K.M., Clum A., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I., Sorek R., Rubin E.
      Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BL21-GoldImported.
    5. "Complete sequence of Escherichia coli BL21(DE3)."
      Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., LaButti K.M., Clum A., Larimer F., Land M., Hauser L., Kyrpides N., Anderson I., Sorek R., Rubin E.
      Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    6. Jeong H., Shim J.-H., Studier F.W., Oh T.K., Kim J.F.
      Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BL21.

    Entry informationi

    Entry nameiC6EEB3_ECOBD
    AccessioniPrimary (citable) accession number: C6EEB3
    Secondary accession number(s): C5WAD8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 1, 2009
    Last sequence update: September 1, 2009
    Last modified: October 1, 2014
    This is version 40 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3